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Valvular heart disease in patients on kidney replacement therapy: “opening Pandora's box�
Rafael de la Espriella, Gregorio Romero-González, Julio Núñez
doi : 10.1093/ckj/sfad060
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1045–1048
Valvular heart disease (VHD) is highly prevalent among dialysis patients, affecting up to 30%–40% of the population. Aortic and mitral valves are the most frequently affected and commonly lead to valvular stenosis and regurgitation.
Estimation of glomerular filtration rate in cardiorenal patients: a step forward
Borja Quiroga, Javier DÃez
doi : 10.1093/ckj/sfad083
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1049–1055
The progressive reduction in estimated glomerular filtration rate (eGFR) resulting in chronic kidney disease (CKD) is associated with increased risk of cardiovascular disease (CVD) (i.e., cardiorenal disease).
Introduction to new CKJ section: In Context – in collaboration with YNP
Amaryllis van Craenenbroeck, Andreas Kronbichler on behalf of YNP of ERA
doi : 10.1093/ckj/sfad052
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Page 1056
Introduction to new CKJ section: In Context – in collaboration with YNP
Amaryllis van Craenenbroeck, Andreas Kronbichler on behalf of YNP of ERA
doi : 10.1093/ckj/sfad052
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Page 1056
Inhibition of clonal expansion of parietal epithelial cells and crescent–podocyte transition in severe glomerulonephritis: on the way to targeted therapy?
Immune abnormalities in IgA nephropathy
Micaela Gentile, Luis Sanchez-Russo, Leonardo V Riella, Alberto Verlato, Joaquin Manrique, Simona Granata, Enrico Fiaccadori, Francesco Pesce, Gianluigi Zaza, Paolo Cravedi
doi : 10.1093/ckj/sfad025
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1059–1070
Immunoglobulin A (IgA) nephropathy (IgAN) is the most common primary glomerulonephritis worldwide and it is characterized by mesangial IgA deposition. Asymptomatic hematuria with various degrees of proteinuria is the most common clinical presentation and up to 20%–40% of patients develop end-stage kidney disease within 20 years after disease onset.
Expanded hemodialysis: what’s up, Doc?
Ana GarcÃa-Prieto, José Carlos de la Flor, Elisabet Coll, Elena Iglesias, Javier Reque, Francisco Valga
doi : 10.1093/ckj/sfad033
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1071–1080
In recent years there has been an increasing interest in expanded hemodialysis (HDx), an emerging renal replacement therapy based on the use of medium cut-off membranes (MCO).
Deprivation and chronic kidney disease—a review of the evidence
Christopher H Grant, Ehsan Salim, Jennifer S Lees, Kate I Stevens
doi : 10.1093/ckj/sfad028
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1081–1091
The relationship between socioeconomic deprivation and health is inequitable. Chronic kidney disease (CKD) is an archetypal disease of inequality, being more common amongst those living in deprivation.
Left-sided valvular heart disease in dialysis recipients: a single-centre observational study
Mohamed Elewa, Sandip Mitra, Anuradha Jayanti
doi : 10.1093/ckj/sfad020
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1092–1101
With the increasing prevalence of chronic kidney disease, the number of people receiving renal replacement is expected to increase by 50% by 2030. Cardiovascular mortality remains significantly higher in this population.
Moderate-to-severe pruritus in untreated or non-responsive hemodialysis patients: results of the French prospective multicenter observational study Pruripreva
Antoine Lanot, Stanislas Bataille, Guy Rostoker, Pierre Bataille, Philippe Chauveau, Maxime Touzot, Laurent Misery
doi : 10.1093/ckj/sfad032
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1102–1112
Chronic kidney disease-associated pruritus (CKD-aP) is a common condition in patients treated with hemodialysis, and has a negative impact on quality of life (QoL). Due to the lack of standardized diagnostic tools and frequent underreporting, pruritus prevalence remains poorly documented.
Association of serum bicarbonate with the development of kidney stones in patients with chronic kidney disease: a retrospective cohort study
Navdeep Tangri, Vandana Mathur, Nancy L Reaven, Susan E Funk, Reid H Whitlock, Donald E Wesson, David A Bushinsky
doi : 10.1093/ckj/sfad034
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1113–1121
Epidemiological studies demonstrate an association between kidney stones and risk of chronic kidney disease (CKD) and CKD progression. Metabolic acidosis, as a consequence of CKD, results in a reduced urine pH which promotes the formation of some types of kidney stones and inhibits the formation of others. While metabolic acidosis is a risk factor for CKD progression, the association of serum bicarbonate with risk of incident kidney stones is not well understood.
A pre-transplantation risk assessment tool for graft survival in Dutch pediatric kidney recipients
Loes Oomen, Huib de Jong, Antonia H M Bouts, Mandy G Keijzer-Veen, Elisabeth A M Cornelissen, Liesbeth L de Wall, Wout F J Feitz, Charlotte M H H T Bootsma-Robroeks
doi : 10.1093/ckj/sfad057
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1122–1131
A prediction model for graft survival including donor and recipient characteristics could help clinical decision-making and optimize outcomes. The aim of this study was to develop a risk assessment tool for graft survival based on essential pre-transplantation parameters.
Syndecan-1 predicts hemodynamic instability in critically ill patients under intermittent hemodialysis
Antônia Cláudia Nascimento de Moura, Sandra Mara Brasileira Mota, Francisco Márcio Tavares Holanda, Gdayllon Cavalcante Meneses, Gabriela Freire Bezerra, Alice Maria Costa Martins, Alexandre Braga Libório
doi : 10.1093/ckj/sfad043
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1132–1138
Up to 70% of intermittent hemodialysis (IHD) sessions in critically ill patients are complicated by hemodynamic instability. Although several clinical characteristics have been associated with hemodynamic instability during IHD, the discriminatory capacity of predicting such events during IHD sessions is less defined.
Effect of ultrafiltration on cerebral small-vessel disease and related outcomes in hemodialysis
Lin Shi, Ke Zheng, Yujun Qian, Fei Han, Hui You, Jing Yuan, Haiyun Wang, Dan Song, Dingding Zhang, Feng Feng, Yicheng Zhu, Xuemei Li
doi : 10.1093/ckj/sfad042
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1139–1148
Increasing evidence suggests a high prevalence of cerebral small-vessel disease (CSVD) in hemodialysis patients. Variable ultrafiltration during hemodialysis may contribute to brain lesions by inducing hemodynamic instability. We aimed to investigate the effect of ultrafiltration on CSVD and relative outcome in this population.
Decreasing incidence of dialysis in older patients in The Netherlands as compared with other European countries: an international perspective
Mathijs van Oevelen, Alferso C Abrahams, Tiny Hoekstra, Marc A G J ten Dam, Anneke Kramer, Kitty J Jager, Gurbey Ocak, Marjolijn van Buren, Willem Jan W Bos
doi : 10.1093/ckj/sfad048
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1149–1159
After decades of increasing dialysis incidence, we observed a decreasing trend in the Netherlands in the last decade. We compared this trend with trends in other European countries.
Rationale and design of CONTINUITY: a Phase 4 randomized controlled trial of continued post-discharge sodium zirconium cyclosilicate treatment versus standard of care for hyperkalemia in chronic kidney disease
James O Burton, Alaster M Allum, Alpesh Amin, Cecilia Linde, Eva Lesén, Carl Mellström, James M Eudicone, Manish M Sood
doi : 10.1093/ckj/sfad053
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1160–1169
Individuals with chronic kidney disease (CKD) hospitalized with hyperkalemia are at risk of hyperkalemia recurrence and re-hospitalization.
Trajectories of systolic blood pressure decline in kidney transplant donors prior to circulatory death and delayed graft function
Yingxin Lin, Armando Teixeira-Pinto, Jonathan C Craig, Helen Opdam, Jeremy C Chapman, Henry Pleass, Angus Carter, Natasha M Rogers, Christopher E Davies, Stephen McDonald, Jean Yang, Wai H Lim, Germaine Wong
doi : 10.1093/ckj/sfad047
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1170–1179
Kidneys donated after circulatory death suffer a period of functional warm ischaemia before death, which may lead to early ischaemic injury. Effects of haemodynamic trajectories during the agonal phase on delayed graft function (DGF) is unknown. We aimed to predict the risk of DGF using patterns of trajectories of systolic blood pressure (SBP) declines in Maastricht category 3 kidney donors.
Proteomic profile of uninvolved versus crescentic glomeruli in MPO-ANCA-associated vasculitis
Amit Sethi, Joseph Grande, Ulrich Specks, Fernando C Fervenza
doi : 10.1093/ckj/sfad030
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1180–1182
De novo immune complex–mediated membranoproliferative glomerulonephritis after COVID-19 vaccination
Nikola Zagorec, Martin Bojić, Dino Kasumović, Petar Šenjug, Danica Galešić Ljubanović, Krešimir Galešić, Ivica Horvatić
doi : 10.1093/ckj/sfad056
Clinical Kidney Journal, Volume 16, Issue 7, July 2023, Pages 1183–1185
