Journal of Neuro-Ophthalmology

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سفارش

Diagnostic Test Basics: A Primer for Neuro-Ophthalmologists

Nolan-Kenney, Rachel C.; Wang, Yuyan; Liu, Mengling

doi : 10.1097/WNO.0000000000001149

Journal of Neuro-Ophthalmology. 40(4):445-449, December 2020.

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Temporal Artery Biopsy in the Workup of Giant Cell Arteritis: Diagnostic Considerations in a Veterans Administration Cohort

Selby, Laura D.; Park-Egan, Brenna A. M.; Winges, Kimberly M.

doi : 10.1097/WNO.0000000000001040

Journal of Neuro-Ophthalmology. 40(4):450-456, December 2020.

Giant cell arteritis (GCA) is the most common systemic vasculitis in the American population older than 50 years and is a sight-threatening and life-threatening disease. It is definitively diagnosed with a temporal artery biopsy.

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Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy

Catarino, Claudia B.; von Livonius, Bettina; Priglinger, Claudia; Banik, Rudrani; Matloob, Selma; Tamhankar, Madhura A.; Castillo, Lorena; Friedburg, Christoph; Halfpenny, Christopher A.; Lincoln, John A.; Traber, Ghislaine L.; Acaroglu, G?lge; Black, Graeme C. M.; Doncel, Carlos; Fraser, Clare L.; Jakubaszko, Joanna; Landau, Klara; Langenegger, Stefan J.; Mu?oz-Negrete, Francisco J.; Newman, Nancy J.; Poulton, Joanna; Scoppettuolo, Elisabetta; Subramanian, Prem; Toosy, Ahmed T.; Vidal, Mariona; Vincent, Andrea L.; Votruba, Marcela; Zarowski, Marcin; Zermansky, Adam; Lob, Felice; Rudolph, Günther; Mikazans, Oskars; Silva, Magda; Ll?ria, Xavier; Metz, Günther; Klopstock, Thomas

doi : 10.1097/WNO.0000000000001023

Journal of Neuro-Ophthalmology. 40(4):558-565, December 2020.

Leber hereditary optic neuropathy (LHON) leads to bilateral central vision loss. In a clinical trial setting, idebenone has been shown to be safe and to provide a trend toward improved visual acuity, but long-term evidence of effectiveness in real-world clinical practice is sparse.

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Cerebral Venous Sinus Thrombosis in the COVID-19 Pandemic

Medicherla, Chaitanya B.; Pauley, Rachel A.; de Havenon, Adam; Yaghi, Shadi; Ishida, Koto; Torres, Jose L.

doi : 10.1097/WNO.0000000000001122

Journal of Neuro-Ophthalmology. 40(4):457-462, December 2020.

Recent studies have noted concern for increased thromboembolic events in the setting of Coronavirus Disease 2019 (COVID-19). Cerebral venous sinus thrombosis (CVST) is a form of thromboembolism that has been observed as a neuro-ophthalmologic complication of COVID-19.

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Secondary Stroke Prevention and Management for the Neuro-Ophthalmologist

Abdul Rahman, Line; Wabnitz, Ashley M.; Turan, Tanya N.

doi : 10.1097/WNO.0000000000001133

Journal of Neuro-Ophthalmology. 40(4):463-471, December 2020.

This article will serve as a comprehensive review of secondary prevention of ischemic stroke and central and branch retinal artery ischemia, which are closely linked pathologically and can be managed similarly to prevent further reoccurrence.

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Acute Care and Treatment of Migraine

Konstantinos, Spingos; Vikelis, Michail; Rapoport, Alan

doi : 10.1097/WNO.0000000000001053

Journal of Neuro-Ophthalmology. 40(4):472-484, December 2020.

Migraine is a chronic neurological disease involving the brain and its vasculature, typically characterized by recurrent attacks of moderate or severe throbbing headache, accompanied by sensitivity to light and sound, and associated with nausea, vomiting, and inability to move due to worsening of pain

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Referral Patterns in Neuro-Ophthalmology

Stunkel, Leanne; Mackay, Devin D.; Bruce, Beau B.; Newman, Nancy J.; Biousse, Valérie

doi : 10.1097/WNO.0000000000000846

Journal of Neuro-Ophthalmology. 40(4):485-493, December 2020.

Neuro-ophthalmologists specialize in complex, urgent, vision- and life-threatening problems, diagnostic dilemmas, and management of complex work-ups.

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Variability of Consecutive Lumbar Puncture Opening Pressures

Kilgore, Khin P.; Bhatti, M. Tariq; Cutsforth-Gregory, Jeremy K.; Hodge, David O.; Chen, John J.

doi : 10.1097/WNO.0000000000000834

Journal of Neuro-Ophthalmology. 40(4):494-497, December 2020.

Lumbar puncture (LP) opening pressures (OPs) are known to fluctuate based on diurnal, environmental, and pathologic conditions. Despite their dynamic nature, single OPs are often deemed sufficient for diagnosis of elevated intracranial pressures (ICPs) in nonspecialists' hands.

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Enhanced Depth Imaging Optical Coherence Tomography of Optic Nerve Head Drusen in Children

Sim, Peng Yong; Soomro, Hibba; Karampelas, Michael; Barampouti, Faye

doi : 10.1097/WNO.0000000000000845

Journal of Neuro-Ophthalmology. 40(4):498-503, December 2020.

To assess the utility of enhanced depth imaging optical coherence tomography (EDI-OCT), compared with other conventional imaging modalities, for detecting and characterizing optic nerve head drusen (ONHD) in children.

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Postoperative Horner Syndrome After Lung Transplantation

Go, Jonathan A.; Vickers, Aroucha; Kaleekal, Thomas S.; Beaver, Hilary A.; Lee, Andrew G.

doi : 10.1097/WNO.0000000000000848

Journal of Neuro-Ophthalmology. 40(4):504-506, December 2020.

Horner syndrome arises from a disruption along the oculosympathetic efferent chain and can be caused by a variety of pathological and iatrogenic etiologies. We present 3 cases of postoperative Horner syndrome after bilateral lung transplantation.

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Catastrophic Allergic Fungal Sinusitis: A Report of Two Cases

Walter, Eyal; McKean, Erin L.; Camelo-Piragua, Sandra I.; Parmar, Hemant A.; Trobe, Jonathan D.

doi : 10.1097/WNO.0000000000000833

Journal of Neuro-Ophthalmology. 40(4):507-513, December 2020.

Allergic fungal rhinosinusitis (AFRS) is a common condition in which sinusitis develops as an IgE-mediated response to common sinonasal fungal organisms. If that response leads to blockage of sinus ostia, bone expansion and erosion by expansive cysts containing dense inspissated debris may occur with the potential for critical neurovascular compression including damage to the anterior visual pathway.

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Validity of International Classification of Diseases Codes for Identifying Neuro-Ophthalmic Disease in Large Data Sets: A Systematic Review

Hamedani, Ali G.; De Lott, Lindsey B.; Deveney, Tatiana; Moss, Heather E.

doi : 10.1097/WNO.0000000000000971

Journal of Neuro-Ophthalmology. 40(4):514-519, December 2020.

Administrative health claims data have been used for research in neuro-ophthalmology, but the validity of International Classification of Diseases (ICD) codes for identifying neuro-ophthalmic conditions is unclear.

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Visual Outcomes in Leber Hereditary Optic Neuropathy Patients With the m.11778G>A (MTND4) Mitochondrial DNA Mutation

Newman, Nancy J.; Carelli, Valerio; Taiel, Magali; Yu-Wai-Man, Patrick

doi : 10.1097/WNO.0000000000001045

Journal of Neuro-Ophthalmology. 40(4):547-557, December 2020.

Leber hereditary optic neuropathy (LHON) is a maternally inherited bilaterally blinding optic neuropathy, predominantly affecting otherwise healthy young individuals, mostly men. The visual prognosis is generally poor, with most patients worsening to at least 20/200 visual acuity.

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Isolated Cranial Nerve 6 Palsy in 6 Patients With COVID-19 Infection

Greer, Christine E.; Bhatt, Jaydeep M.; Oliveira, Cristiano A.; Dinkin, Marc J.

doi : 10.1097/WNO.0000000000001146

Journal of Neuro-Ophthalmology. 40(4):520-522, December 2020.

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Hallucinatory Palinopsia in COVID-19-Induced Posterior Reversible Encephalopathy Syndrome

Ghosh, Ritwik; Lahiri, Durjoy; Dubey, Souvik; Ray, Biman K.; Benito-Le?n, Juli?n

doi : 10.1097/WNO.0000000000001135

Journal of Neuro-Ophthalmology. 40(4):523-526, December 2020.

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Novel Mutations of mtDNA m.14568G>A/m.14568C>T in MT-ND6 and m.7299A>G in MT-CO1: Evidence of Pathogenicity in Leber Hereditary Optic Neuropathy

Rizk, Maria; Dunya, Ibrahim; Azar, Georges; Seif, Roland; Megarbane, Andre; Sadaka, Ama

doi : 10.1097/WNO.0000000000000973

Journal of Neuro-Ophthalmology. 40(4):566-568, December 2020.

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Variable Presentation of Leber Hereditary Optic Neuropathy in Children of a Family Harboring a Rare m.13051G>A mtDNA Mutation

Smirnov, Vasily M.; Cuisset, Jean-Marie; Marks, Caroline; Debruyne, Philippe; Dhaenens, Claire-Marie; Defoort-Dhellemmes, Sabine

doi : 10.1097/WNO.0000000000001083

Journal of Neuro-Ophthalmology. 40(4):569-571, December 2020.

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Application of Hemifield Visual Electrophysiology to Diagnose Functional Vision Loss

Moss, Heather E.; Jabbehdari, Sayena

doi : 10.1097/WNO.0000000000000882

Journal of Neuro-Ophthalmology. 40(4):527-529, December 2020.

Neuro-ophthalmologists frequently see patients who are experiencing vision loss not accounted for by a neuro-ophthalmic disorder. In this article, we describe a case of binasal hemianopia in an otherwise healthy 65-year-old woman who was initially diagnosed with glaucoma but ultimately proved to have functional visual loss. This diagnosis was made by confirming by confirming normal visual pathway function using hemifield visual-evoked potential studies.

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Arteritic Orbital Ischemia Producing Afferent and Efferent Pupillary Defects

Hussain, Mariam; Kini, Ashwini; Al Othman, Bayan; Ponce, Claudia Prospero; Li, Helen; Lee, Andrew G.

doi : 10.1097/WNO.0000000000000838

Journal of Neuro-Ophthalmology. 40(4):530-532, December 2020.

A 67-year-old woman presented with acute loss of vision to no light perception (NLP), a right afferent pupillary defect, and anisocoria with a nonreactive and dilated pupil in the right eye. Fundus examination showed pallid optic disc edema and a central retinal artery occlusion (CRAO) in the right eye. A temporal artery biopsy showed giant cell arteritis (GCA). Orbital involvement in GCA has been reported previously. However the combination of an afferent and efferent pupillary defect, NLP vision, pallid disc edema, and a CRAO in an elderly patient is likely a unique clinical combination that should strongly suggest GCA. Clinicians should be aware of the myriad presentations of GCA, including orbital ischemia.

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A 26-Year-Old Woman With Diplopia and Nystagmus

Anderson, William J.; Sharma, Aseem; Guzman, Miguel A.; Chung, Sophia M

doi : 10.1097/WNO.0000000000000959

Journal of Neuro-Ophthalmology. 40(4):533-537, December 2020.

A 26-year-old woman presented for a routine contact lens evaluation but was found to have a subtle right sixth nerve paresis and adducting nystagmus of the left eye. She reported horizontal diplopia on far right gaze as well as subjective right-sided weakness and poor balance for 1 year. Brain and spinal MRI revealed multiple cystic lesions with variable enhancement throughout the posterior fossa and cervical spinal cord.

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