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American Journal of Respiratory and Critical Care Medicine
doi : 10.1164/rccm.20612Pxliv Â
Volume 206, Issue 12 | December 15 2022
Postextubation Respiratory Support: One More Piece to the Puzzle
Oriol Roca 1,2,3, LluÃÂs Blanch 1,2, and Gonzalo Hernández 4
Better to Be an Agnostic than a Believer (at Least in Pulmonary Fibrosis)
Giacomo Sgalla and Luca Richeldi
New Insights into the Epigenomic Landscape of Small-Cell Lung Cancer: A Game Changer?
Poonam Sarode 1, Soni Savai Pullamsetti 1,2,3, and Rajkumar Savai 1,2,3,4
New Tools for Old Problems: Gastroesophageal Reflux Disease and the Lung Allograft Microbiome
Allan R. Glanville 1 and Alicia B. Mitchell 2
Lung Allograft Dysfunction: Does Aspiration Hold the Key?
Alexa A. Pragman 1,2
Understanding Genotype–Phenotype Correlations in Patients with TBX4 Mutations: New Views Inside and Outside the Box
Mary P. Mullen 1,2
Breath of Fresh Air: Toward Unraveling the Molecular Underpinnings of Sleep Apnea
Brian E. Cade 1,2 and Sina A. Gharib 3
High-Flow Versus VenturiMask Oxygen Therapy to Prevent Reintubation in Hypoxemic Patients after Extubation: A Multicenter Randomized Clinical Trial
Salvatore Maurizio Maggiore 1,2, Samir Jaber 3,4, Domenico Luca Grieco 5, Jordi Mancebo 6, Spyros Zakynthinos 7, Alexandre Demoule 8,9, Jean-Damien Ricard 10, Paolo Navalesi 11, Rosanna Vaschetto 12,13, Sami Hraiech 14, Kada Klouche 15,16, Jean-Pierre Frat 17,18, Virginie Lemiale 19, Vito Fanelli 20,21, Gerald Chanques 3,4, Daniele Natalini 4, Eleni Ischaki 6, Danielle Reuter 8,9, Indalecio Morán 5, Béatrice La Combe 8, Federico Longhini 22, Andrea De Gaetano 23,24, V. Marco Ranieri 25, Laurent J. Brochard 26,27, Massimo Antonelli
Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis
Farida Ahangari 1*, Christine Becker 2,3*, Daniel G. Foster 4, Maurizio Chioccioli 1, Meghan Nelson 4, Keriann Beke 4, Xing Wang 2,3, Aurelien Justet 1,5, Taylor Adams 1, Benjamin Readhead 2,6, Carly Meador 4, Kelly Correll 4, Loukia N. Lili 2, Helen M. Roybal 4, Kadi-Ann Rose 1, Shuizi Ding 1, Thomas Barnthaler 1,7, Natalie Briones 4, Giuseppe DeIuliis 1, Jonas C. Schupp 1, Qin Li 1, Norihito Omote 1, Yael Aschner 4, Lokesh Sharma 1, Katrina W. Kopf 4, Björn Magnusson 8, Ryan Hicks 9, Anna Backmark 8, Charles S. Dela Cruz 1, Ivan Rosas 10, Leslie P. Cousens 11, Joel T. Dudley 2, Naftali Kaminski 1*, and Gregory P. Downey
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer
Ranran Kong 1,2,3, Ayushi S. Patel 2,3,4, Takashi Sato 2,3,5,6, Feng Jiang 2,3, Seungyeul Yoo 7,8, Li Bao 9, Abhilasha Sinha 2,3, Yang Tian 2,3, Maya Fridrikh 2,3, Shuhui Liu 10, Jie Feng 11, Xijing He 12,13, Jiantao Jiang 1, Yuefeng Ma 1, Karina Grullon 2,3, Dawei Yang 2,3,14, Charles A. Powell 2,3, Mary Beth Beasley 15, Jun Zhu 3,7,8, Eric L. Snyder 16,17,18, Shaomin Li 1*, and Hideo Watanabe 2,3,7* ... Show less
Lung Allograft Microbiome Association with Gastroesophageal Reflux, Inflammation, and Allograft Dysfunction
Pierre H. H. Schneeberger 1,2,3,4*, Chen Yang Kevin Zhang 1,2,5*, Jessica Santilli 1,2,3, Bo Chen 6, Wei Xu 6, Youngho Lee 1,2,3, Zonelle Wijesinha 1,2,3, Elaine Reguera-Nuñez 1,2,3, Noelle Yee 1,2,3, Musawir Ahmed 3,5, Kristen Boonstra 5, Rayoun Ramendra 5, Courtney W. Frankel 7, Scott M. Palmer 7, Jamie L. Todd 7, Tereza Martinu 1,2,3,5‡, and Bryan Coburn 1,2,3‡
The Lung Allograft Microbiome Associates with Pepsin, Inflammation, and Primary Graft Dysfunction
John E. McGinniss 1, Samantha A. Whiteside 1, Rebecca A. Deek 2, Aurea Simon-Soro 1, Jevon Graham-Wooten 1, Michelle Oyster 1, Melanie D. Brown 1, Edward Cantu 3, Joshua M. Diamond 1, Hongzhe Li 2, Jason D. Christie 1, Frederic D. Bushman 4, and Ronald G. Collman 1,4 ... Show less
First Genotype–Phenotype Study in TBX4 Syndrome: Gain-of-Function Mutations Causative for Lung Disease
Matina Prapa 1,2,*, Mauro Lago-Docampo 3,4,*, Emilia M. Swietlik 1,5,6, David Montani 7, Mélanie Eyries 8, Marc Humbert 7, Carrie L. Welch 9, Wendy K. Chung 9,10, Rolf M. F. Berger 11, Harm Jan Bogaard 12, Olivier Danhaive 13,14, Pilar Escribano-SubÃÂas 15,16, Henning Gall 11, Barbara Girerd 7, Ignacio Hernandez-Gonzalez 17, Simon Holden 18, David Hunt 19, Samara M. A. Jansen 12, Wilhelmina Kerstjens-Frederikse 20, David G. Kiely 21,22, Pablo Lapunzina 23,24,25, John McDermott 26,27, Shahin Moledina 28, Joanna Pepke-Zaba 6, Gary J. Polwarth 6, Gwen Schotte 12, Jair Tenorio-Castaño 23,24,25, A. A. Roger Thompson 21,22, John Wharton 29, Stephen J. Wort 29, Karyn Megy 1,5, Rutendo Mapeta 1,5, Carmen M. Treacy 1, Jennifer M. Martin 1, Wei Li 1, Andrew J. Swift 21, Paul D. Upton 1, Nicholas W. Morrell 1,5,6,30, Stefan Gräf 1,30,31, Diana Valverde 3,4, NIHR BioResource for Translational Research–Rare Diseases32, National Cohort Study of Idiopathic and Heritable PAH33, and PAH Biobank Enrolling Centers’ Investigators33 ... Show less
Genome-Wide Association Study of Obstructive Sleep Apnea and Objective Sleep-related Traits Identifies Novel Risk Loci in Han Chinese Individuals
Huajun Xu 1,2*, Feng Liu 1,2*, Zhiqiang Li 3,4*, Xinyi Li 1,2, Yuenan Liu 1,2, Niannian Li 1,2, Xiaoxu Zhang 1,2, Zhenfei Gao 1,2, Xiaoman Zhang 1,2, Yupu Liu 1,2, Jianyin Zou 1,2, Lili Meng 1,2, Suru Liu 1,2, Huaming Zhu 1,2, Xulan Tang 1,2, Hongmin Wu 1,2, Kaiming Su 1,2, Bin Chen 1,2, Dongzhen Yu 1,2, Haibo Ye 1,2, Haoyan Chen 5, Hongliang Yi 1,2, Shankai Yin 1,2‡, Jian Guan 1,2‡, and Yongyong Shi 3,4‡ ... Show less
Extensive Pulmonary Cyst Formation in Erdheim-Chester Disease
Shiyao Wang 1,2,3,4, Jun Li 1,2,3,4, Yanhong Ren 1,2,3,4, Min Liu 5, Bei Wang 6, and Huaping Dai 1,2,3,4
Redistribution of Perfusion by Prone Positioning Improves Shunt in a Patient with Unilateral Lung Injury
Douglas Slobod 1,2, Elena Spinelli 1, Gaetano Scaramuzzo 3, Alfredo Lissoni 1, Giacomo Grasselli 1,4, and Tommaso Mauri 1,4
Selected Bibliography of Recent Research in COVID-19
Benjamin D. Singer 1,2,3,4, Sanjay H. Chotirmall 5,6, Lindsay M. Leither 7,8, Oliver W. Meldrum 5, Anthony M. Joudi 1,3, Nitin Seam 9, Samuel M. Brown 7,8*, and Başak Çoruh 10*
Dying with OSA, or from It: A Cautionary Note about Novel Hypoxia Metrics
Jonathan C. Jun *
Metatranscriptomics of Nasopharyngeal Microbiota and Host Distinguish between Pneumonia and Health
Priyanka Nannapaneni 1, John Sundh 2, Stefanie Prast-Nielsen 1, Samuel Rhedin 1,3, Åke Örtqvist 1, Pontus Naucler 1, and Birgitta Henriques-Normark 1,4*
Taking for Granted Conclusions from Studies that Cannot Prove Causality of Respiratory Symptoms and Vaping
Davide Campagna 1* and Grazia Caci 2
Reply to Campagna and Caci: Taking for Granted Conclusions from Studies that Cannot Prove Causality of Respiratory Symptoms and Vaping
Wubin Xie 1 and Andrew C. Stokes 1,2*
Reply to Campagna and Caci: Taking for Granted Conclusions from Studies that Cannot Prove Causality of Respiratory Symptoms and Vaping
Jonathan D. Klein *
The Challenges of Estimating Causal Effects of Continuous Positive Airway Pressure Therapy from Observational Data
Lucas M. Donovan 1,2* and Sanjay R. Patel 3
Reply to Donovan and Patel
Sébastien Bailly 1, Chloé Gervès-Pinquié 2, and Frédéric Gagnadoux 3*;
Erratum: Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial
