Deirdre K Tobias, Clemens Wittenbecher, Frank B Hu
doi : 10.1093/ajcn/nqab124
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1385–1387
Chen Yuan, Kimmie Ng
doi : 10.1093/ajcn/nqab133
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1388–1389
Sarah Detlefs, Jacquelyn M Powers
doi : 10.1093/ajcn/nqab056
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1390–1391
Nicolaas P Pronk
doi : 10.1093/ajcn/nqab083
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1392–1393
Eamonn M M Quigley
doi : 10.1093/ajcn/nqab084
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1394–1395
Luisa Fernandez-Chirino, Neftali Eduardo Antonio-Villa, Omar Yaxmehen Bello-Chavolla
doi : 10.1093/ajcn/nqab085
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1396–1397
Gülistan Bahat
doi : 10.1093/ajcn/nqab107
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1398–1399
Curtis Tilves, Noel T Mueller
doi : 10.1093/ajcn/nqab108
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1400–1401
Denise L Jacobson, Daniela Neri, Audrey Gaskins, Lynn Yee, Armando J Mendez, Kristy Hendricks, Suzanne Siminski, Rebecca Zash, Laurie Hyzy, Jennifer Jao, Pediatric HIV/AIDS Cohort Study
doi : 10.1093/ajcn/nqaa441
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1402–1410
Women living with HIV (WLHIV) have a higher prevalence of anemia than women without HIV, possibly related to the effects of HIV and antiretroviral medications.
Caoileann H Murphy, Ellen M Flanagan, Giuseppe De Vito, Davide Susta, Kathleen A J Mitchelson, Elena de Marco Castro, Joan M G Senden, Joy P B Goessens, Agnieszka Mik?osz, Adrian Chabowski, Ricardo Segurado, Clare A Corish, Sinead N McCarthy, Brendan Egan, Luc J C van Loon, Helen M Roche
doi : 10.1093/ajcn/nqaa449
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1411–1427
Leucine-enriched protein (LEU-PRO) and long-chain (LC) n–3 (?–3) PUFAs have each been proposed to improve muscle mass and function in older adults, whereas their combination may be more effective than either alone.
Pirjo Komulainen, Jaakko Tuomilehto, Kai Savonen, Reija M?nnikk?, Maija Hassinen, Timo A Lakka, Tuomo H?nninen, Vesa Kiviniemi, David R Jacobs, Jr, Miia Kivipelto, Rainer Rauramaa
doi : 10.1093/ajcn/nqab018
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1428–1439
Evidence for the effects of exercise and dietary interventions on cognition from long-term randomized controlled trials (RCTs) in large general populations remains insufficient.
Young H Cho, Sang Y Lee, Chang-Hyung Lee, Jong-Hwan Park, Yong S So
doi : 10.1093/ajcn/nqaa447
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1440–1446
Studies suggest that Schisandra chinensis Baillon (Sc) may enhance muscle strength and mass because of its anti-inflammatory and antioxidant properties.
Moniek van Zutphen, Hendriek C Boshuizen, Marlou-Floor Kenkhuis, Evertine Wesselink, Anne J M R Geijsen, Johannes H W de Wilt, Henk K van Halteren, Ernst Jan Spillenaar Bilgen, Eric T P Keulen, Maryska L G Janssen-Heijnen, Stéphanie O Breukink, Martijn J L Bours, Dieuwertje E Kok, Renate M Winkels, Matty P Weijenberg, Ellen Kampman, Fr?nzel J B van Duijnhoven
doi : 10.1093/ajcn/nqaa394
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1447–1457
An unhealthy lifestyle is associated with the risk of colorectal cancer (CRC), but it is unclear whether overall lifestyle after a CRC diagnosis is associated with risks of recurrence and mortality.
Daniel Boakye, Lina Jansen, Ben Sch?ttker, Eugene H J M Jansen, Niels Halama, Haifa Maalmi, Xin Gào, Jenny Chang-Claude, Michael Hoffmeister, Hermann Brenner
doi : 10.1093/ajcn/nqaa405
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1458–1467
Vitamin D plays a role in detoxifying free radicals, which might explain the previously reported lower mortality in colorectal cancer (CRC) patients with higher vitamin D concentrations.
Janna L Koole, Martijn J L Bours, Anne J M R Geijsen, Biljana Gigic, Arve Ulvik, Dieuwertje E Kok, Stefanie Brezina, Jennifer Ose, Andreas Baierl, Jürgen B?hm, Hermann Brenner, Stéphanie O Breukink, Jenny Chang-Claude, Fr?nzel J B van Duijnhoven, Peter van Duijvendijk, Tanja Gumpenberger, Nina Habermann, Henk K van Halteren, Michael Hoffmeister, Andreana N Holowatyj, Maryska L G Janssen-Heijnen, Eric T P Keulen, Rama Kiblawi, Flip M Kruyt, Christopher I Li, Tengda Lin, ?ivind Midttun, Anita R Peoples, Eline H van Roekel, Martin A Schneider, Petra Schrotz-King, Alexis B Ulrich, Kathy Vickers, Evertine Wesselink, Johannes H W de Wilt, Andrea Gsur, Per M Ueland, Cornelia M Ulrich, Ellen Kampman, Matty P Weijenberg
doi : 10.1093/ajcn/nqaa422
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1468–1481
B vitamins have been associated with the risk and progression of colorectal cancer (CRC), given their central roles in nucleotide synthesis and methylation, yet their association with quality of life in established CRC is unclear.
Justin C Brown, Bette J Caan, Elizabeth M Cespedes Feliciano, Jingjie Xiao, Erin Weltzien, Carla M Prado, Candyce H Kroenke, Adrienne Castillo, Marilyn L Kwan, Jeffrey A Meyerhardt
doi : 10.1093/ajcn/nqaa440
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1482–1489
There is an emerging viewpoint that change in body weight is not sufficiently sensitive to promptly identify clinically meaningful change in body composition, such as skeletal muscle depletion.
Konstantinos K Tsilidis, Nikos Papadimitriou, Niki Dimou, Dipender Gill, Sarah J Lewis, Richard M Martin, Neil Murphy, Georgios Markozannes, Verena Zuber, Amanda J Cross, Kimberley Burrows, David S Lopez, Timothy J Key, Ruth C Travis, Aurora Perez-Cornago, David J Hunter, Fr?nzel J B van Duijnhoven, Demetrius Albanes, Volker Arndt, Sonja I Berndt, Stéphane Bézieau, D Timothy Bishop, Juergen Boehm, Hermann Brenner, Andrea Burnett-Hartman, Peter T Campbell, Graham Casey, Sergi Castellv?-Bel, Andrew T Chan, Jenny Chang-Claude, Albert de la Chapelle, Jane C Figueiredo, Steven J Gallinger, Graham G Giles, Phyllis J Goodman, Andrea Gsur, Jochen Hampe, Heather Hampel, Michael Hoffmeister, Mark A Jenkins, Temitope O Keku, Sun-Seog Kweon, Susanna C Larsson, Loic Le Marchand, Christopher I Li, Li Li, Annika Lindblom, Vicente Mart?n, Roger L Milne, Victor Moreno, Hongmei Nan, Rami Nassir, Polly A Newcomb, Kenneth Offit, Paul D P Pharoah, Elizabeth A Platz, John D Potter, Lihong Qi, Gad Rennert, Lori C Sakoda, Clemens Shafmayer, Martha L Slattery, Linda Snetselaar, Jeanette Schenk, Stephen N Thibodeau, Cornelia M Ulrich, Bethany Van Guelpen, Sophia Harlid, Kala Visvanathan, Ludmila Vodickova, Hansong Wang, Emily White, Alicja Wolk, Michael O Woods, Anna H Wu, Wei Zheng, Bas Bueno-de-Mesquita, Marie-Christine Boutron-Ruault, David J Hughes, Paula Jakszyn, Tilman Kühn, Domenico Palli, Elio Riboli, Edward L Giovannucci, Barbara L Banbury, Stephen B Gruber, Ulrike Peters, Marc J Gunter on behalf of GECCO, CORECT, and CCFR
doi : 10.1093/ajcn/nqab003
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1490–1502
The literature on associations of circulating concentrations of minerals and vitamins with risk of colorectal cancer is limited and inconsistent. Evidence from randomized controlled trials (RCTs) to support the efficacy of dietary modification or nutrient supplementation for colorectal cancer prevention is also limited.
Zhendong Mei, Guo-Chong Chen, Zheng Wang, Mykhaylo Usyk, Bing Yu, Yoshiki Vazquez Baeza, Greg Humphrey, Rodolfo Salido Benitez, Jun Li, Jessica S Williams-Nguyen, Martha L Daviglus, Lifang Hou, Jianwen Cai, Yan Zheng, Rob Knight, Robert D Burk, Eric Boerwinkle, Robert C Kaplan, Qibin Qi
doi : 10.1093/ajcn/nqab001
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1503–1514
Trimethylamine-N-oxide (TMAO), a diet-derived and gut microbiota–related metabolite, is associated with cardiovascular disease (CVD). However, major dietary determinants and specific gut bacterial taxa related to TMAO remain to be identified in humans.
Bocheng Xu, Jie Fu, Yanxiang Qiao, Jinping Cao, Edward C Deehan, Zhi Li, Mingliang Jin, Xinxia Wang, Yizhen Wang
doi : 10.1093/ajcn/nqaa435
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1515–1530
Microbiota-accessible carbohydrates (MACs) are critical substrates for intestinal microbes; the subsequent production of SCFAs may have some potential benefits for patients with type 2 diabetes mellitus (T2DM).
Yawen Zhang, Lijun Feng, Xin Wang, Mark Fox, Liang Luo, Lijun Du, Binrui Chen, Xiaoli Chen, Huiqin He, Shuwen Zhu, Zhefang Hu, Shujie Chen, Yanqin Long, Yubin Zhu, Li Xu, Yanyong Deng, Benjamin Misselwitz, Brian M Lang, Bahtiyar Yilmaz, John J Kim, Chung Owyang, Ning Dai
doi : 10.1093/ajcn/nqab005
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1531–1545
The efficacy and factors associated with patient outcomes for a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (LFD) compared with traditional dietary advice (TDA) based on modified National Institute for Clinical Excellence guidelines for irritable bowel syndrome with diarrhea (IBS-D) in regions consuming a non-Western diet are unclear.
David C Love, Catherine Turvey, Jamie Harding, Ruth Young, Rebecca Ramsing, Michael F Tlusty, Jillian P Fry, Ly Nguyen, Frank Asche, Elizabeth M Nussbaumer, Andrew L Thorne-Lyman, Martin Bloem
doi : 10.1093/ajcn/nqaa437
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1546–1555
Seafood has a nutritional profile that can be beneficial to human health, which gives it a role to play in healthy diets. In addition, because its production and harvesting can have fewer environmental impacts than some forms of animal protein, it can contribute to sustainable diets. However, the positive health and environmental outcomes are not guaranteed—they depend on how seafood is prepared and served and whether it is sourced from sustainable fisheries and aquaculture industries.
Akriti Singh, Shibani Ghosh, Honorine Ward, Mark J Manary, Beatrice L Rogers, Irwin H Rosenberg
doi : 10.1093/ajcn/nqaa434
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1556–1564
Environmental enteric dysfunction (EED) may influence growth during and recovery from moderate acute malnutrition (MAM), however, biomarkers to assess these relations have yet to be identified.
Ma?gorzata A Desmond, Jakub G Sobiecki, Maciej Jaworski, Pawe? P?udowski, Jolanta Antoniewicz, Meghan K Shirley, Simon Eaton, Janusz Ksi??yk, Mario Cortina-Borja, Bianca De Stavola, Mary Fewtrell, Jonathan C K Wells
doi : 10.1093/ajcn/nqaa445
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1565–1577
Plant-based diets (PBDs) are increasingly recommended for human and planetary health. However, comprehensive evidence on the health effects of PBDs in children remains incomplete, particularly in vegans.
Dena Zeraatkar, Arrti Bhasin, Rita E Morassut, Isabella Churchill, Arnav Gupta, Daeria O Lawson, Anna Miroshnychenko, Emily Sirotich, Komal Aryal, David Mikhail, Tauseef A Khan, Vanessa Ha, John L Sievenpiper, Steven E Hanna, Joseph Beyene, Russell J de Souza
doi : 10.1093/ajcn/nqab002
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1578–1592
Dietary recommendations and policies should be guided by rigorous systematic reviews. Reviews that are of poor methodological quality may be ineffective or misleading. Most of the evidence in nutrition comes from nonrandomized studies of nutritional exposures (usually referred to as nutritional epidemiology studies), but to date methodological evaluations of the quality of systematic reviews of such studies have been sparse and inconsistent.
Matthew J Belanger, Christina C Wee, Kenneth J Mukamal, Edgar R Miller, III, Frank M Sacks, Lawrence J Appel, Robert H Shmerling, Hyon K Choi, Stephen P Juraschek
doi : 10.1093/ajcn/nqaa424
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1593–1599
Dietary recommendations to prevent gout emphasize a low-purine diet. Recent evidence suggests that the Dietary Approaches to Stop Hypertension (DASH) diet reduces serum urate while also improving blood pressure and lipids.
Suzanne Filteau, George PrayGod, Andrea M Rehman, Robert Peck, Kidola Jeremiah, Rikke Krogh-Madsen, Daniel Faurholt-Jepsen
doi : 10.1093/ajcn/nqaa438
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1600–1608
The prevalence, pathology, and existence of malnutrition-associated diabetes remain uncertain, especially with respect to adult-acquired undernutrition.
Soriah M Harvey, Vanessa E Murphy, Olivia M Whalen, Peter G Gibson, Megan E Jensen
doi : 10.1093/ajcn/nqaa442
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1609–1618
The risk of wheezing is high in infancy and is heightened in infants with a family history of asthma/atopy. The role of breastfeeding in influencing respiratory health for these high-risk infants is unclear.
Rosario Ortol?, Esther Garc?a-Esquinas, Antonio Bu?o-Soto, Mercedes Sotos-Prieto, Ellen A Struijk, Francisco Félix Caballero, Esther Lopez-Garcia, José R Banegas, Fernando Rodr?guez-Artalejo
doi : 10.1093/ajcn/nqaa444
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1619–1626
Growth differentiation factor 15 (GDF-15) is a biomarker for aging and chronic disease burden that may capture the anti-inflammatory and antioxidant effects attributed to healthy diets.
Aleix Sala-Vila, Eider M Arenaza-Urquijo, Gonzalo S?nchez-Benavides, Marc Su?rez-Calvet, Marta Milà-Alomà, Oriol Grau-Rivera, José M Gonz?lez-de-Ech?varri, Marta Crous-Bou, Carolina Minguill?n, Karine Fauria, Grégory Operto, Carles Falc?n, Gemma Salvad?, Raffaele Cacciaglia, Silvia Ingala, Frederik Barkhof, Helmut Schr?der, Nikolaos Scarmeas, Juan-Domingo Gispert, José L Molinuevo, for the ALFA study
doi : 10.1093/ajcn/nqab016
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1627–1635
The number of APOE-?4 alleles is a major nonmodifiable risk factor for sporadic Alzheimer disease (AD). There is increasing evidence on the benefits of dietary DHA (22:6n–3) before the onset of AD symptoms, particularly in APOE-?4 carriers. Brain alterations in the preclinical stage can be detected by structural MRI.
Xing Liu, Wanshui Yang, Kana Wu, Shuji Ogino, Weibing Wang, Na He, Andrew T Chan, Zuo-Feng Zhang, Jeffrey A Meyerhardt, Edward Giovannucci, Xuehong Zhang
doi : 10.1093/ajcn/nqab059
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1636–1646
To evaluate the association between postdiagnostic dairy intake and survival among patients with colorectal cancer (CRC).
Xiao Xu, Zhikai Yang, Tiantian Ma, Ziqian Li, Yuan Chen, Yingdong Zheng, Jie Dong
doi : 10.1093/ajcn/nqaa431
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1647–1656
In chronic kidney disease (CKD), determining energy expenditure is the precondition for recommending energy intake in nutrition management.
Cornelia Speich, Comlan Evariste S Mitchikpè, Colin I Cercamondi, Christophe Zeder, Gary M Brittenham, Diego Moretti, Michael B Zimmermann
doi : 10.1093/ajcn/nqaa433
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1657–1669
Long-term isotopic dilution measurements of body iron may allow quantification of basal body iron balance and iron gains during an iron intervention with higher precision and accuracy than conventional iron indices.
David A Horita, Sunil Hwang, Julie M Stegall, Walter B Friday, David R Kirchner, Steven H Zeisel
doi : 10.1093/ajcn/nqaa439
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1670–1678
Choline deficiency has numerous negative health consequences; although the preponderance of the US population consumes less than the recommended Adequate Intake (AI), clinical assessment of choline status is difficult. Further, several pathways involved in primary metabolism of choline are estrogen-sensitive and the AI for premenopausal women is lower than that for men.
Maria Cristina Gonzalez, Ali Mehrnezhad, Nariman Razaviarab, Thiago G Barbosa-Silva, Steven B Heymsfield
doi : 10.1093/ajcn/nqab029
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1679–1687
Calf circumference (CC) is used in geriatric studies as a simple and practical skeletal muscle (SM) marker for diagnosing low SM and sarcopenia. Currently applied CC cutoff points were developed in samples including older participants; values representative of the full adult lifespan are lacking.
Julie M Petersen, Mahsa M Yazdy, Kelly D Getz, Marlene T Anderka, Martha M Werler, National Birth Defects Prevention Study
doi : 10.1093/ajcn/nqaa436
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1688–1699
Research suggests short interpregnancy intervals increase risks for adverse perinatal outcomes, including some birth defects. A hypothesized cause is nutritional depletion, including folic acid (FA).
William S Harris, Nathan L Tintle, JoAnn E Manson, Adam H Metherel, Jennifer G Robinson
doi : 10.1093/ajcn/nqaa443
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1700–1706
The factors other than dietary intake that determine tissue concentrations of EPA and DHA remain obscure. Prior studies suggested that, in women, endogenous estrogen may accelerate synthesis of DHA from ?-linolenic acid (ALA), but the effects of exogenous estrogen on RBC n–3 (?-3) PUFA concentrations are unknown.
Jesse Sheftel, Devika J Suri, Sherry A Tanumihardjo
doi : 10.1093/ajcn/nqab104
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1707–1708
Nimmathota Arlappa
doi : 10.1093/ajcn/nqab105
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1708–1709
G Bhanuprakash Reddy, Raghu Pullakhandam, Santu Ghosh, Naveen Boiroju, Shalini Tattari, Avula Laxmaiah, Rajkumar Hemalatha, Umesh Kapil, Harshpal S Sachdev, Anura V Kurpad
doi : 10.1093/ajcn/nqab106
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1709–1711
Jacob J Christensen, Vibeke H Telle-Hansen, Stine M Ulven, Petri T Kovanen, Matti Jauhiainen, Katariina ??rni, Kirsten B Holven
doi : 10.1093/ajcn/nqab110
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1711–1712
Marit K Zin?cker, Karianne Svendsen, Kandice R Levental, Ilya Levental, Simon N Dankel
doi : 10.1093/ajcn/nqab111
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1712–1713
Henry S Kahn
doi : 10.1093/ajcn/nqab141
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Pages 1713–1714
doi : 10.1093/ajcn/nqab003
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1715
doi : 10.1093/ajcn/nqab155
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1715
doi : 10.1093/ajcn/nqab190
The American Journal of Clinical Nutrition, Volume 113, Issue 6, June 2021, Page 1716
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