دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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The impact of frailty on the management of atrial fibrillation
Stephanie L. Harrison, Søren P. Johnsen, Gregory Y.H. Lip
doi : 10.18632/aging.204918
Volume 15, Issue 14
Peritoneal signalling improves hippocampal BDNF expression in aged mice
Yoshinori Takei, Yoko Amagase, Atsushi Sugiyama
doi : 10.18632/aging.204919
The theory of orchid and dandelion offers a new subtyping framework for cognitive aging
Sylvain Moreno, Emma Rodrigues, Faranak Farzan
doi : 10.18632/aging.204955
A novel theory of ageing independent of damage accumulation
James Wordsworth, Daryl Shanley
doi : 10.18632/aging.204956
Towards disease-oriented dosing of rapamycin for longevity: does aging exist or only age-related diseases?
Mikhail V. Blagosklonny
doi : 10.18632/aging.204920
Human senescent fibroblasts trigger progressive lung fibrosis in mice
Fernanda Hernandez-Gonzalez, Neus Prats, Valentina Ramponi, José Alberto López-DomÃnguez, Kathleen Meyer, Mònica Aguilera, MarÃa Isabel Muñoz MartÃn, Daniel MartÃnez, Alvar Agusti, Rosa Faner, Jacobo Sellarés, Federico Pietrocola, Manuel Serrano
doi : 10.18632/aging.204825
Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span
Natalya Kaverina, R. Allen Schweickart, Gek Cher Chan, Joseph C. Maggiore, Diana G. Eng, Yuting Zeng, Sierra R. McKinzie, Hannah S. Perry, Adilijiang Ali, Christopher O’Connor, Beatriz Maria Veloso Pereira, Ashleigh B. Theberge, Joshua C. Vaughan, Carol J. Loretz, Anthony Chang, Neil A. Hukriede, Markus Bitzer, Jeffrey W. Pippin, Oliver Wessely, Stuart J. Shankland
doi : 10.18632/aging.204897
Parallel shift of DNA methylation and gene expression toward the mean in mouse spleen with aging
Sangkyun Jeong, Sunwha Cho, Seung Kyoung Yang, Soo A. Oh, Yong-Kook Kang
doi : 10.18632/aging.204903
Sirt3 regulates NLRP3 and participates in the effects of plantainoside D on acute lung injury sepsis
Jing Wang, Wanrong Li, Fang Zhao, Qianqian Han, Lingling Shan, Yumei Qian
doi : 10.18632/aging.204628
Th1 promotes M1 polarization of intestinal macrophages to regulate colitis-related mucosal barrier damage
Shuiliang Ruan, Liang Xu, Yongjia Sheng, Jin Wang, Xiaohong Zhou, Caiqun Zhang, Li Guo, Wenyan Li, Chenyang Han
doi : 10.18632/aging.204629
Establishing a prognostic model based on five starvation-related long non-coding RNAs for clear cell renal cell carcinoma
Zhou Yu, Guo Chen, Zhenwei Feng, Yang Li, Haitao Yu, Wei Shi, Xin Gou, Chunlin Zhang, Xiang Peng
doi : 10.18632/aging.204816
Alleviation of D-gal-induced senile liver injury by Rg3, a signature component of red ginseng
Ke Xu, Biwen Hu, Xuhui Ding, Zhengyu Zhan
doi : 10.18632/aging.204819
PARP10 is highly expressed and associated with inferior outcomes in acute myeloid leukemia
Ling Wang, Chuang Jiang, Dandan Hu
doi : 10.18632/aging.204832
Prognostic analysis of lung adenocarcinoma based on cancer-associated fibroblasts genes using scRNA-sequencing
Han Zhang, Yuhang Wang, Kai Wang, Yun Ding, Xin Li, Shuai Zhao, Xiaoteng Jia, Daqiang Sun
doi : 10.18632/aging.204838
Molecular subtypes based on DNA sensors predict prognosis and tumor immunophenotype in hepatocellular carcinoma
Hong-Sheng Lin, Wen-Peng Pang, Hao Yuan, Yin-Zhi Kong, Fu-Li Long, Rong-Zhen Zhang, Li Yang, Qiao-Ling Fang, Ai-Ping Pan, Xiao-Hui Fan, Ming-Fen Li
doi : 10.18632/aging.204870
S14G-Humanin ameliorates ovalbumin-induced airway inflammation in asthma mediated by inhibition of toll-like receptor 4 (TLR4) expression and the nuclear factor κ-B (NF-κB)/early growth response protein-1 (Egr-1) pathway
Bo Su, Ran Li, Fuxing Song, Min Liu, Xianjun Sun
doi : 10.18632/aging.204874
Oxidized phospholipids facilitate calcific aortic valve disease by elevating ATF4 through the PERK/eIF2α axis
Xiaohua Zhu, Linjie Yang, Xu Han, Chen Huang, Gongcheng Huang, Tingju Wei, Liliang Shu, Jing Xu
doi : 10.18632/aging.204875
The integration of machine learning and multi-omics analysis provides a powerful approach to screen aging-related genes and predict prognosis and immunotherapy efficacy in hepatocellular carcinoma
Jiahui Shen, Han Gao, Bowen Li, Yan Huang, Yinfang Shi
doi : 10.18632/aging.204876
Comprehensive analysis of the role of a four-gene signature based on EMT in the prognosis, immunity, and treatment of lung squamous cell carcinoma
Feng Li, Hui Wang, Can Wang, Yun Li, Jing-Yan Song, Ke-Yi Fan, Chao Li, Quan-Lin Ma, Qi Yu, Shuang-Ping Zhang
doi : 10.18632/aging.204878
Celastrol impairs tumor growth by modulating the CIP2A-GSK3β-MCL-1 axis in gastric cancer cells
Jin Wu, Feng Ye, Tao Xu
doi : 10.18632/aging.204879
Exosome-coated polydatin nanoparticles in the treatment of radiation-induced intestinal damage
Qiu Chen, Lei Yao, Quanbin Liu, Jun Hou, Xinyu Qiu, Mengyuan Chen, Zhuojun Wu, Duanmin Hu, Fengmei Cui, Tao Yan
doi : 10.18632/aging.204882
Exosomal lnc-CDHR derived from human umbilical cord mesenchymal stem cells attenuates peritoneal epithelial-mesenchymal transition through AKT/FOXO pathway
Taiwei Jiao, Yuling Huang, Haiyan Sun, Lina Yang
doi : 10.18632/aging.204883
Combined surface functionalization of MSC membrane and PDA inhibits neurotoxicity induced by Fe3O4 in mice based on apoptosis and autophagy through the ASK1/JNK signaling pathway
Yang Li, Te Liu, Xiuying Li, Modi Yang, Tianxin Liu, Jindian Bao, Miao Jiang, Lingling Hu, Yuzhuo Wang, Pu Shao, Jinlan Jiang
doi : 10.18632/aging.204884
Single-cell sequencing analysis reveals the relationship between tumor microenvironment cells and oxidative stress in breast cancer bone metastases
Minmin Zhang, Xiao Chai, Li Wang, Ke Mo, Wenyang Chen, Xiangtao Xie
doi : 10.18632/aging.204885
Characterization of platelet-related genes and constructing signature combined with immune-related genes for predicting outcomes and immunotherapy response in lung squamous cell carcinoma
Siyi Zhao, Han Gong, Wenhua Liang
doi : 10.18632/aging.204886
miRNA-186-5p inhibits migration, invasion and proliferation of breast cancer cells by targeting SBEM
Hui Hao, Bingsheng Wang, Lin Yang, Yinzhou Sang, Wei Xu, Wei Liu, Lili Zhang, Da Jiang
doi : 10.18632/aging.204887
KNTC1 and MCM2 are the molecular targets of gallbladder cancer
Wei Jia, Chao Wang
doi : 10.18632/aging.204889
Single-cell transcriptomics reveals the drivers and therapeutic targets of lymph node metastasis in lung adenocarcinoma
Xin Ji, Zihao Wang, Guige Wang, Lijun Tang, Zhijun Han
doi : 10.18632/aging.204890
Exploring molecular markers and drug candidates for colorectal cancer through comprehensive bioinformatics analysis
Guangyao Li, JiangPeng Zhu, Lulu Zhai
doi : 10.18632/aging.204891
Identifying the oncogenic roles of FAP in human cancers based on systematic analysis
Chao Ma, Shuaishuai Xi, He Sun, Meng Zhang, Yuanmin Pei
doi : 10.18632/aging.204892
Severe pneumonia induces immunosenescence of T cells in the lung of mice
Qingle Ma, Chenhui Weng, Chenlu Yao, Jialu Xu, Bo Tian, Yi Wu, Heng Wang, Qianyu Yang, Huaxing Dai, Yue Zhang, Fang Xu, Xiaolin Shi, Chao Wang
doi : 10.18632/aging.204893
Comparative analyses of the prognosis, tumor immune microenvironment, and drug treatment response between left-sided and right-sided colon cancer by integrating scRNA-seq and bulk RNA-seq data
Lichao Cao, Shenrui Zhang, Danni Yao, Ying Ba, Qi Weng, Jin Yang, Hezi Zhang, Yanan Ren
doi : 10.18632/aging.204894
A novel LncRNA SPIRE1/miR-181a-5p/PRLR axis in mandibular bone marrow–derived mesenchymal stem cells regulates the Th17/Treg immune balance through the JAK/STAT3 pathway in periodontitis
Bingyi Shao, Duo Zhou, Jie Wang, Deqin Yang, Jing Gao
doi : 10.18632/aging.204895
Combining WGCNA and machine learning to construct immune-related EMT patterns to predict HCC prognosis and immune microenvironment
Yating Sun, Shengfu He, Mingyang Tang, Ding Zhang, Bao Meng, Jiawen Yu, Yanyan Liu, Jiabin Li
doi : 10.18632/aging.204898
Identification and validation of a novel overall survival prediction model for immune-related genes in bone metastases of prostate cancer
Wen Bi, Weiming Guo, Gang Fan, Lei Xie, Changqing Jiang
doi : 10.18632/aging.204900
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing
Kai Huang, Hao Wu, Xiangyang Xu, Lujia Wu, Qin Li, Lin Han
doi : 10.18632/aging.204901
Metastasis-related gene signature associates with immunity and predicts prognosis accurately in patients with osteosarcoma
Sen Qin, Lei Li, Da Liu
doi : 10.18632/aging.204902
Non-SMC condensin I complex subunit D2 (NCAPD2) reveals its prognostic and immunologic features in human cancers
Xiaoying Dong, Ting Liu, Zhizhao Li, Yongzhen Zhai
doi : 10.18632/aging.204904
The lipid peroxidation-derived DNA adduct γ-OHPdG as a diagnostic and prognostic biomarker in hepatocellular carcinoma
Qiwei Cao, Yazhou Zhang, Hongtao Liu, Yuxia Cheng, Mingxin Liu, Hai Zhao, Ruixue Tang, Junying Sun, Sophia Xu, Bing Sun, Qing Sun
doi : 10.18632/aging.204910
Active components and molecular mechanisms of Sagacious Confucius’ Pillow Elixir to treat cognitive impairment based on systems pharmacology
Zhitao Hou, Xinyu Yang, Ling Jiang, Liying Song, Yang Li, Dongdong Li, Yanning Che, Xiuling Zhang, Zhongren Sun, Hongcai Shang, Jing Chen
doi : 10.18632/aging.204912
Subcellular localization of nucleolar protein 14 and its proliferative function mediated by miR-17-5p and E2F4 in pancreatic cancer
Yong-Xing Du, Ying Zhou, Xiao-Hao Zheng, Yun-Jie Duan, Zong-Ting Gu, Ye-Feng Yin, Cheng-Feng Wang
doi : 10.18632/aging.204915
The Eph/Ephrin system in primary bone tumor and bone cancer pain
Lujuan Wang, Wei Li, Yong Pan
doi : 10.18632/aging.204852
Retraction: CircNF1-419 improves the gut microbiome structure and function in AD-like mice
Chen Diling, Qi Longkai, Guo Yinrui, Liu Yadi, Tang Xiaocui, Zhu Xiangxiang, Zeng Miao, Li Ran, Shuai Ou, Wang Dongdong, Xie Yizhen, Yuan Xujiang, Burton B. Yang, Wu Qingping
doi : 10.18632/aging.204905
