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PME-1-regulated neural cell death: new therapeutic opportunities?
Liesbeth Guffens, Rita Derua, Veerle Janssens
doi : 10.18632/aging.205303
Volume 15, Issue 21
Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model
Qing Cao, Manasa Kumar, Allea Frazier, Jamal B. Williams, Shengkai Zhao, Zhen Yan
doi : 10.18632/aging.205057
Parental age effect on the longevity and healthspan in Drosophila melanogaster and Caenorhabditis elegans
Camille Lenzi, Alexis Piat, Pascal Schlich, Judith Ducau, Jean-Claude Bregliano, Hugo Aguilaniu, Anne Laurençon
doi : 10.18632/aging.205098
1,5-anhydro-D-fructose induces anti-aging effects on aging-associated brain diseases by increasing 5’-adenosine monophosphate-activated protein kinase activity via the peroxisome proliferator-activated receptor-γ co-activator-1α/brain-derived neurotrophic factor pathway
Kiyoshi Kikuchi, Shotaro Otsuka, Seiya Takada, Kazuki Nakanishi, Kentaro Setoyama, Harutoshi Sakakima, Eiichiro Tanaka, Ikuro Maruyama
doi : 10.18632/aging.205228
Antibiotics that target mitochondria extend lifespan in C. elegans
Gloria Bonuccelli, Darren R. Brooks, Sally Shepherd, Federica Sotgia, Michael P. Lisanti
doi : 10.18632/aging.205229
Hub gene identification and molecular subtype construction for Helicobacter pylori in gastric cancer via machine learning methods and NMF algorithm
Lianghua Luo, Ahao Wu, Xufeng Shu, Li Liu, Zongfeng Feng, Qingwen Zeng, Zhonghao Wang, Tengcheng Hu, Yi Cao, Yi Tu, Zhengrong Li
doi : 10.18632/aging.205053
Systematic analysis of glutamine metabolism family genes and exploration of the biological role of GPT in colorectal cancer
Weiqi Dai, Wenhui Mo, Wenqiang Xu, Dengyu Han, Xuanfu Xu
doi : 10.18632/aging.205079
RAI2 acts as a tumor suppressor with functional significance in gastric cancer
Xiaoli Lou, Wei Deng, Lixiong Shuai, Yijing Chen, Mengmeng Xu, Jingze Xu, Yongsheng Zhang, Yongyou Wu, Zhifei Cao
doi : 10.18632/aging.205135
Capsaicin alleviates doxorubicin-induced acute myocardial injury by regulating iron homeostasis and PI3K-Akt signaling pathway
Longbin Wang, Ying Liu, Si Li, Zhijian Zha, Yu Chen, Qi Wang, Shujing Zhou, Xufeng Huang, Ming Xu
doi : 10.18632/aging.205138
Lipid reprogramming induced by the NNMT-ABCA1 axis enhanced membrane fluidity to promote endometrial cancer progression
Qirong Wen, Xiaohui Xie, Caiyuan Chen, Bolun Wen, Yaqiong Liu, Jie Zhou, Xiaobin Lin, Han Jin, Kun Shi
doi : 10.18632/aging.205142
MicroRNA-30a-3p: a potential noncoding RNA target for the treatment of arteriosclerosis obliterans
Mao Zhang, Yu Chen, Fang Niu, Xiaohui Luo, Jiangping Li, Wei Hu
doi : 10.18632/aging.205154
Comprehensive analysis reveals XCL2 as a cancer prognosis and immune infiltration-related biomarker
Wu Chen, Fan Zou, Tianbao Song, Yuqi Xia, Ji Xing, Ting Rao, Xiangjun Zhou, Jinzhuo Ning, Sheng Zhao, Weimin Yu, Fan Cheng
doi : 10.18632/aging.205156
The development and experimental validation of hypoxia-related long noncoding RNAs prognostic signature in predicting prognosis and immunotherapy of cutaneous melanoma
Gang Wang, Yuliang Sun, Qingjia Xu
doi : 10.18632/aging.205157
Integrated analysis of single-cell and bulk RNA-sequencing data reveals the prognostic value and molecular function of THSD7A in gastric cancer
Kaiyu Shen, Binyu Chen, Liu Yang, Wencang Gao
doi : 10.18632/aging.205158
Identification of epithelial-mesenchymal transition-related biomarkers in lung adenocarcinoma using bioinformatics and lab experiments
Yuanjun Cheng, Yumei Shen, Qianru Fang, Shanzhou Duan, Yifei Wang, Xiaoxiao Dai, Yongbing Chen
doi : 10.18632/aging.205159
Inhibition of keloid by 32P isotope radiotherapy through suppressing TGF-β/Smad signaling pathway
Long Xie, Liqun Huang, Guanjie Zhang, Yingrui Su
doi : 10.18632/aging.205160
Hepatoprotective effect of syringin combined with costunolide against LPS-induced acute liver injury in L-02 cells via Rac1/AKT/NF-κB signaling pathway
Jingxin Mao, Lihong Tan, Cheng Tian, Wenxiang Wang, Hao Zhang, Zhaojing Zhu, Yan Li
doi : 10.18632/aging.205161
Utility of G protein-coupled oestrogen receptor 1 as a biomarker for pan-cancer diagnosis, prognosis and immune infiltration: a comprehensive bioinformatics analysis
Yu-Chao Fan, Wen Wu, Xue-Feng Leng, Hong-Wei Zhang
doi : 10.18632/aging.205162
The role of m6A RNA methylation regulator in meningioma
Yu Yang, Liqin Luo, Zhiwu Zhou
doi : 10.18632/aging.205163
Identification and diagnostic potential of serum microRNAs as biomarkers for early detection of Alzheimer’s disease
Ying-Hao Han, Hong-Yi Xiang, Dong Hun Lee, Lin Feng, Hu-Nan Sun, Mei-Hua Jin, Taeho Kwon
doi : 10.18632/aging.205165
Collaborating single-cell and bulk RNA sequencing for comprehensive characterization of the intratumor heterogeneity and prognostic model development for bladder cancer
Jie Wang, Zili Zuo, Zongze Yu, Zhigui Chen, Lisa Jia Tran, Jing Zhang, Jinsong Ao, Fangdie Ye, Zhou Sun
doi : 10.18632/aging.205166
USP14 predicts poorer survival outcomes and promotes tumor progression in endometrial carcinoma by activating NF-κB signaling
Xiaojin Gong, Li Jia, Lili Zhou, Tongxiu Hu
doi : 10.18632/aging.205168
Multi-omics analysis reveals PUS1 triggered malignancy and correlated with immune infiltrates in NSCLC
doi : 10.18632/aging.205169
Identification of circRNA-miRNA-mRNA network as biomarkers for interstitial cystitis/bladder pain syndrome
Shi-Qin Yang, Liao Peng, Le-De Lin, Yuan-Zhuo Chen, Meng-Zhu Liu, Chi Zhang, Jia-Wei Chen, De-Yi Luo
doi : 10.18632/aging.205170
CENPB promotes the proliferation of hepatocellular carcinoma and is directly regulated by miR-29a
Xuyang Wang, Laibang Luo, Youfu Zhang, Gang Liu, Zehong Fang, Zhidan Xu, Xuguang Hu
doi : 10.18632/aging.205171
N7-methylguanosine-related miRNAs predict hepatocellular carcinoma prognosis and immune therapy
Liping Ma, Qingwei Ma, Qiaomei Deng, Jilu Zhou, Yingpei Zhou, Qianqian Wei, Zhihu Huang, Xiaoxia Lao, Ping Du
doi : 10.18632/aging.205172
Effects of amyloid β (Aβ)42 and Gasdermin D on the progression of Alzheimer’s disease in vitro and in vivo through the regulation of astrocyte pyroptosis
Wenjuan Hong, Chengping Hu, Can Wang, Binggen Zhu, Ming Tian, Hongyun Qin
doi : 10.18632/aging.205174
Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin
Yuqi Xin, Qingkun Jiang, Chenshu Liu, Jiaxuan Qiu
doi : 10.18632/aging.205175
Polyphyllin I attenuates the invasion and metastasis via downregulating GRP78 in drug-resistant hepatocellular carcinoma cells
Haiyan Du, Haochen Wu, Qinyang Kang, Mianmian Liao, Meirong Qin, Ning Chen, Houshuang Huang, Danping Huang, Ping Wang, Guangdong Tong
doi : 10.18632/aging.205176
Influences and mechanism of erythropoietin on the cognitive function of vascular dementia rats
Zhipeng Tang, Xiuqin Li, Nan Yin, Ming Zhao, Qingchuan Hu, Peiyuan Lv
doi : 10.18632/aging.205178
Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma
Zhenyong Xiao, Jinwei Li, Cong Liang, Yamei Liu, Yuxiu Zhang, Yuxia Zhang, Quan Liu, Xianlei Yan
doi : 10.18632/aging.205179
A systematic framework for identifying prognostic necroptosis-related lncRNAs and verification of lncRNA CRNDE/miR-23b-3p/IDH1 regulatory axis in glioma
Yangxia Chen, Di Hu, Fang Wang, Cheng Huang, Hesong Xie, Ling Jin
doi : 10.18632/aging.205180
Cuproptosis-related gene DLAT serves as a prognostic biomarker for immunotherapy in clear cell renal cell carcinoma: multi-database and experimental verification
Shuaishuai Huang, Congbo Cai, Kena Zhou, Xue Wang, Xue Wang, Dong Cen, Guobin Weng
doi : 10.18632/aging.205181
A robust six-gene prognostic signature based on two prognostic subtypes constructed by chromatin regulators is correlated with immunological features and therapeutic response in lung adenocarcinoma
Qiang Chen, Hongbo Zhao, Jing Hu
doi : 10.18632/aging.205183
CCL19: a novel prognostic chemokine modulates the tumor immune microenvironment and outcomes of cancers
Qiang Gu, Shifang Zhou, Cong Chen, Zhi Wang, Wenhao Xu, Jiarong Zhang, Shiyin Wei, Jianfeng Yang, Hongjing Chen
doi : 10.18632/aging.205184
A neural network model was constructed by screening the potential biomarkers of aortic dissection based on genes associated with pyroptosis
Cheng Chen, Lulu Gao, Hongwei Ge, Weibin Huang, Rong Zhao, Renjun Gu, Ziyun Li, Xin Wang
doi : 10.18632/aging.205187
Shenmai injection ameliorates doxorubicin-induced myocardial injury by suppressing autophagy-apoptosis via miR-30a
Yanyang Li, Lu Fan, Xiaoming Wang, Shichao Lv
doi : 10.18632/aging.205188
Construction and validation of a novel angiogenesis pattern to predict prognosis and immunotherapy efficacy in colorectal cancer
Zhiyong Li, Yang Liu, Peng Guo, Yunwei Wei
doi : 10.18632/aging.205189
Abnormal low expression of SFTPC promotes the proliferation of lung adenocarcinoma by enhancing PI3K/AKT/mTOR signaling transduction
Baile Zuo, Lin Wang, Xiaoyan Li, Xin Li, Jinping Wang, Yanlu Xiong, Jie Lei, Xi Zhang, Yifan Chen, Qiongwen Liu, Jinke Jiao, Mengru Sui, Jinhan Fan, Ningxue Wu, Zewen Song, Guoyin Li
doi : 10.18632/aging.205191
lncRNA HOXC-AS2 promotes the progression of hypopharyngeal cancer by binding to the P62 protein mediating the autophagy process
Yuandi Xiang, Guoquan Huang, Jie Wang, Qingquan Hua
doi : 10.18632/aging.205192
Ferulic acid ameliorates the quality of in vitro-aged bovine oocytes by suppressing oxidative stress and apoptosis
Yi-Jing Yin, Yong-Hong Zhang, Yu Wang, Hao Jiang, Jia-Bao Zhang, Shuang Liang, Bao Yuan
doi : 10.18632/aging.205193
Oxidative stress and autophagy-mediated immune patterns and tumor microenvironment infiltration characterization in gastric cancer
Jifeng Liu, Biao Zhang, Yunshu Zhang, Huahui Zhao, Xu Chen, Lei Zhong, Dong Shang
doi : 10.18632/aging.205194
Cyclosporin A-mediated translocation of HuR improves MTX-induced cognitive impairment in a mouse model via NCOA4-mediated ferritinophagy
Huang Ding, Rong Xiang, Yifan Jia, Jishi Ye, Zhongyuan Xia
doi : 10.18632/aging.205195
D-galactose causes sinoatrial node dysfunction: from phenotype to mechanism
Heng Zhang, Chen Chen, Yue Liu, Wei Chen, Jing Qi, Yue Xu, Lu Ren, Guanlin Yang, Dongyu Min, Zhuang Liu, Xintong Cai, Miao Hao, Guanzhen Xu, Ping Hou
doi : 10.18632/aging.205196
Identification and validation of ubiquitination-related signature and subgroups in immune microenvironment of tuberculosis
Peipei Zhou, Jie Shen, Xiao Ge, Haien Cheng, Yanli Sun, Meng Li, Heng Li, Zhengjun Yi, Zhenpeng Li
doi : 10.18632/aging.205198
Characterization of the immune cell function landscape in head and neck squamous carcinoma to assist in prognosis prediction and immunotherapy
Wenlun Wang, Zhouyi Zhang, Wenming Li, Dongmin Wei, Jianing Xu, Ye Qian, Shengda Cao, Dapeng Lei
doi : 10.18632/aging.205201
High-mobility group box-1 impedes skeletal muscle regeneration via downregulation of Pax-7 synthesis by increasing miR-342-5p expression
Trung-Loc Ho, Yu-Liang Lai, Chin-Jung Hsu, Chen-Ming Su, Chih-Hsin Tang
doi : 10.18632/aging.205202
KIFC1 promotes proliferation and pseudo-bipolar division of ESCC through the transportation of Aurora B kinase
Bin Du, Lingyu Wei, Jia Wang, Yanyan Li, Jing Huo, Jinsheng Wang, Pu Wang
doi : 10.18632/aging.205203
Discovery and identification of the prognostic significance and potential mechanism of FMO2 in breast cancer
Lichun Wu, Jie Chu, Lijuan Shangguan, Mingfei Cao, Feng Lu
doi : 10.18632/aging.205204
Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
Xiaoqing Wu, Wenping Lu, Weixuan Zhang, Dongni Zhang, Heting Mei, Mengfan Zhang, Yongjia Cui, Zhili Zhuo
doi : 10.18632/aging.205205
Retraction for: Cationic solid lipid nanoparticles loaded by integrin β1 plasmid DNA attenuates IL-1β-induced apoptosis of chondrocyte
Yuejiang Zhao, Hanwen Chen, Lu Wang, Zhiyuan Guo, Shijie Liu, Simin Luo
doi : 10.18632/aging.205326
