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Exploring clonal hematopoiesis and its impact on aging, cancer, and patient care
Julieta Elena Rodriguez, Jean Baptiste Micol, Capucine Baldini
doi : 10.18632/aging.205404
Volume 15, Issue 24
Mapping of the gene network that regulates glycan clock of ageing
Azra Frkatović-Hodžić, Anika Mijakovac, Karlo Miškec, Arina Nostaeva, Sodbo Z. Sharapov, Arianna Landini, Toomas Haller, Erik van den Akker, Sapna Sharma, Rafael R. C. Cuadrat, Massimo Mangino, Yong Li, Toma Keser, Najda Rudman, Tamara Štambuk, Maja Pu�ić-Baković, Irena Trbojević-Akma�ić, Ivan Gudelj, Jerko Štambuk, Tea Pribić, Barbara Radovani, Petra Tominac, Krista Fischer, Marian Beekman, Manfred Wuhrer, Christian Gieger, Matthias B. Schulze, Clemens Wittenbecher, Ozren Polasek, Caroline Hayward, James F. Wilson, Tim D. Spector, Anna Köttgen, Frano Vu�ković, Yurii S. Aulchenko, Aleksandar Vojta, Jasminka Krištić, Lucija Klarić, Vlatka Zoldoš, Gordan Lauc
doi : 10.18632/aging.205106
Systemic changes induced by autologous stem cell ovarian transplant in plasma proteome of women with impaired ovarian reserves
Anna Buigues, Noelia RamÃrez-Martin, Jessica MartÃnez, Nuria Pellicer, Marcos Meseguer, Antonio Pellicer, Sonia Herraiz
doi : 10.18632/aging.205400
Age-related alterations in the oscillatory dynamics serving verbal working memory processing
Seth D. Springer, Hannah J. Okelberry, Madelyn P. Willett, Hallie J. Johnson, Chloe E. Meehan, Mikki Schantell, Christine M. Embury, Maggie P. Rempe, Tony W. Wilson
doi : 10.18632/aging.205403
SRSF7 downregulation induces cellular senescence through generation of MDM2 variants
Jiwon Hong, Seongki Min, Gyesoon Yoon, Su Bin Lim
doi : 10.18632/aging.205420
The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS)
Jinhua Yan, Ling Yao, Ying Tan, Yue Wang
doi : 10.18632/aging.205024
Integrated analysis and validation of the TRIM28-H2AX-CDK4 diagnostic model assists to predict the progression of HCC
Qifei Tian, Guofang Lu, Ying Ma, Lingling Ma, Yulong Shang, Ni Guo, Yan Huang, Lin Zhu, Rui Du
doi : 10.18632/aging.205137
The peptide Acein promotes dopamine secretion through clec-126 to extend the lifespan of elderly C. elegans
Jiaqi Wang, Dong Wang, Sarra Setrerrahmane, Jean Martinez, Han-Mei Xu
doi : 10.18632/aging.205150
Phoenixin-20 ameliorates Sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of the PKA/CREB signaling
Jing Zhang, Zhao Wang, Kun Cong, Jun Qi, Lining Sun
doi : 10.18632/aging.205177
Identification and validation of necroptosis-related gene signatures to predict clinical outcomes and therapeutic responses in acute myeloid leukemia
Xiang-Mei Wen, Zi-Jun Xu, Ji-Chun Ma, Pei-Hui Xia, Ye Jin, Xin-Yi Chen, Wei Qian, Jiang Lin, Jun Qian
doi : 10.18632/aging.205231
Joint effect of RRP9 and DDX21 on development of colorectal cancer and keloid
Hao Liu, Xiaoqian Chi, Ning Yang, Mengjie Shan, Yiding Xiao, Mingzi Zhang, Yan Hao, Shiyang Hou, Yabin Liu, Youbin Wang
doi : 10.18632/aging.205240
Meteorin-like protein elevation post-exercise improved vascular inflammation among coronary artery disease patients by downregulating NLRP3 inflammasome activity
Jingjin Liu, Liwei Diao, Weiyi Xia, Xiaoyi Zeng, Wen Li, Jieru Zou, Tiansheng Liu, Xinli Pang, Yongshun Wang
doi : 10.18632/aging.205268
Anoikis regulator GLI2 promotes NC cell immunity escape by TGF-β-mediated non-classic hedgehog signaling in colorectal cancer: based on artificial intelligence and big data analysis
Zhang Shanshan, Ding Fanfei, Sun Xuan, Lu Huina, Zhang Ye, Li Jiayu, Zhao Shuo, Pan Xue, Pu Yingye, Jin Chengjun, Pan Hang, Li Li
doi : 10.18632/aging.205283
Downregulating miR-184 relieves calcium oxalate crystal-mediated renal cell damage via activating the Rap1 signaling pathway
Mei Han, Donghong Zhang, Junwei Ji, Junli Zhang, Mingyi Qin
doi : 10.18632/aging.205286
Conjoint research of WGCNA, single-cell transcriptome and structural biology reveals the potential targets of IDD development and treatment and JAK3 involvement
Yingjing Zhao, Yuxue Mu, Yujia Zou, Zhijian He, Tianxing Lu, Xinhui Wang, Weihang Li, Bo Gao
doi : 10.18632/aging.205289
IGFBPL1 inhibits macrophage lipid accumulation by enhancing the activation of IGR1R/LXRα/ABCG1 pathway
Lianjie Hou, Xixi Feng, Zhi Zhu, Yali Mi, Qin He, Kai Yin, Guojun Zhao
doi : 10.18632/aging.205301
Investigating the ID3/SLC22A4 as immune-related signatures in ischemic stroke
Dading Lu, Heng Cai, Yugang Li, Wenyuan Chang, Xiu Liu, Qiwei Dai, Wanning Yu, Wangli Chen, Guomin Qiao, Haojie Xie, Xiong Xiao, Zhiqing Li
doi : 10.18632/aging.205308
Bioinformatics-based identification and validation of hub genes associated with aging in patients with coronary artery disease
Wangmeng Zhang, Minmin Zhao, Li Xin, Ximei Qi, Ping Cao, Jiyan Wang, Xin Li
doi : 10.18632/aging.205309
A comprehensive analysis of the prognostic and immunotherapeutic characteristics of KIFC1 in pan-cancer and its role in the malignant phenotype of pancreatic cancer
Shihang Zhang, Ouyang Qin, Huanming Xu, Shu Wu, Wei Huang, Hailiang Song
doi : 10.18632/aging.205311
Exosomal hsa-miR-151a-3p and hsa-miR-877-5p are potential novel biomarkers for predicting bone metastasis in lung cancer
Kun Zhao, Changji Jia, Jin Wang, Weiye Shi, Xiaoying Wang, Yan Song, Changliang Peng
doi : 10.18632/aging.205314
Tenecteplase versus alteplase for patients with acute ischemic stroke: a meta-analysis of randomized controlled trials
Xu Zhang, Teng-Fei Wan, Jing Chen, Liang Liu
doi : 10.18632/aging.205315
Acetylshikonin induces necroptosis via the RIPK1/RIPK3-dependent pathway in lung cancer
Shih-Sen Lin, Tsung-Ming Chang, Augusta I-Chin Wei, Chiang-Wen Lee, Zih-Chan Lin, Yao-Chang Chiang, Miao-Ching Chi, Ju-Fang Liu
doi : 10.18632/aging.205316
hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis
Yu Wang, Zhenlin Li, Jun He, Wenxiang Chen, Yiming Li, Xiangmei Chen, Junjie Liang, Qiangfeng Yu, Jianyin Zhou
doi : 10.18632/aging.205317
LncRNA HAGLROS contribute to papillary thyroid cancer progression by modulating miR-206/HMGA2 expression
Zhaohui Zeng, Shengtao Tang, Liping Chen, Haiwen Hou, Yuan Liu, Juhui Li
doi : 10.18632/aging.205321
Imaging of brain clearance pathways via MRI assessment of the glymphatic system
Yi He, Jitian Guan, Lingfeng Lai, Xiaolei Zhang, Beibei Chen, Xueqing Wang, Renhua Wu
doi : 10.18632/aging.205322
A novel oxidative stress-related gene signature as an indicator of prognosis and immunotherapy responses in HNSCC
Zhuoqi Li, Chunning Zheng, Hongtao Liu, Jiling Lv, Yuanyuan Wang, Kai Zhang, Shuai Kong, Feng Chen, Yongmei Kong, Xiaowei Yang, Yuxia Cheng, Zhensong Yang, Chi Zhang, Yuan Tian
doi : 10.18632/aging.205323
Does enhanced cognitive performance reduce fracture risk? a Mendelian randomization study
Shaoting Luo, Linfang Deng, Yufan Chen, Weizheng Zhou, Federico Canavese, Lianyong Li
doi : 10.18632/aging.205325
ATRX is a predictive marker for endocrinotherapy and chemotherapy resistance in HER2-/HR+ breast cancer through the regulation of the AR, GLI3 and GATA2 transcriptional network
Hongyan Qian, Rui Ji, Cheng Shen, Yinze Wei, Chenyi Sheng, Qichao Ni, Jing Pan, Yifan Chi, Huan You, Ying Miao, Minxin Shi, Xianghua Huang, Aiguo Shen
doi : 10.18632/aging.205327
The efficacy of immune checkpoint inhibitors is limited in elderly NSCLC: a retrospective efficacy study and meta-analysis
Jiaxin Yin, Yuxiao Song, Yang Fu, Wang Jun, Jiazhuo Tang, Zhimin Zhang, Qibin Song, Bicheng Zhang
doi : 10.18632/aging.205328
Seven oxidative stress-related genes predict the prognosis of hepatocellular carcinoma
Chen Miao, Xiao He, Gang Chen, Ulf D. Kahlert, Chenchen Yao, Wenjie Shi, Dongming Su, Liang Hu, Zhihong Zhang
doi : 10.18632/aging.205330
TMX family genes and their association with prognosis, immune infiltration, and chemotherapy in human pan-cancer
Na Luo, Zhiqiang Mei, Qiqi Zhang, Hong Tang, Runlan Wan, Anni Deng, Xiaopan Zou, Chaoxiang Lv
doi : 10.18632/aging.205332
Copper metabolism-related risk score identifies hepatocellular carcinoma subtypes and SLC27A5 as a potential regulator of cuproptosis
Xiaoyan Li, Jinping Wang, Zongliang Guo, Yong Ma, Dawei Xu, Daguang Fan, Peng Dai, Yifan Chen, Qiongwen Liu, Jinke Jiao, Jinhan Fan, Ningxue Wu, Xin Li, Guoyin Li
doi : 10.18632/aging.205334
Long non-coding RNA signature for predicting gastric cancer survival based on genomic instability
Jialing Zhang, Liang Chen, Wei Wei, Fei Mao
doi : 10.18632/aging.205336
Experimental validation and pan-cancer analysis identified COL10A1 as a novel oncogene and potential therapeutic target in prostate cancer
Shengxian Xu, Dongze Liu, Zheng Qin, Zhengxin Liang, Hongbo Xie, Bocun Yi, Kaibin Wang, Gaoteng Lin, Ranlu Liu, Kuo Yang, Yong Xu, Hongtuan Zhang
doi : 10.18632/aging.205337
Reveal the correlation between hub hypoxia/immune-related genes and immunity and diagnosis, and the effect of SAP30 on cell apoptosis, ROS and MDA production in cerebral ischemic stroke
Yue Cao, Wanmei Yao, Rongrong Lu, Huan Zhao, Wenyi Wei, Xiaolei Lei, Zheng Zhang, Biwang Liu
doi : 10.18632/aging.205339
Inhibition of TGF-β1-induced epithelial-mesenchymal transition in gliomas by DMC-HA
Lei Shi, Zhimin Wang, Jun Rong, Xifeng Fei, Xuetao Li, Bao He, Weiyi Gong, Jin Qian
doi : 10.18632/aging.205340
Macrophage-specific deletion of Notch-1 induced M2 anti-inflammatory effect in atherosclerosis via activation of the PI3K-oxidative stress axis
Mingming Zhang, Xiangyong Yue, Xueping Zhao, Yonggang Lu, Hongtao Liu, Zhe Zhang, Huan Ma, Xing Wang, Hanying Xing
doi : 10.18632/aging.205342
A potential therapeutic approach for gastric cancer: inhibition of LACTB transcript 1
Wei Nie, Lihua Hu, Zhiqiang Yan, Yang Wang, Qianyun Shi, Shui He, Qian Wang, Fang Yang
doi : 10.18632/aging.205345
Causal effects of lipid-lowering therapies on aging-related outcomes and risk of cancers: a drug-target Mendelian randomization study
Han Chen, Xinyu Tang, Wei Su, Shuo Li, Ruoyun Yang, Hong Cheng, Guoxin Zhang, Xiaoying Zhou
doi : 10.18632/aging.205347
Pan-cancer analysis of homeodomain-containing gene C10 and its carcinogenesis in lung adenocarcinoma
Xiangyuan Tan, Zhanzhan Li, Huayan Xie, Jiarong Chen, Jian Xiao, Yaofeng Zhi, Haixin Mo, Yanming Huang, Aibin Liu
doi : 10.18632/aging.205348
Integrative transcriptome and single-cell sequencing technology analysis of the potential therapeutic benefits of oleanolic acid in liver injury and liver cancer
Hongji Xu, Qihang Yuan, Zhiqiang Wu, Yingsong Xu, Junhong Chen
doi : 10.18632/aging.205349
Integrated analysis of bulk RNA-seq and single-cell RNA-seq reveals the function of pyrocytosis in the pathogenesis of abdominal aortic aneurysm
Shiqi Zhao, Hai Cang, Ying Liu, Yanjie Huang, Song Zhang
doi : 10.18632/aging.205350
Parvalbumin interneurons dysfunction is potentially associated with FαMNs decrease and NRG1-ErbB4 signaling inhibition in spinal cord in amyotrophic lateral sclerosis
Qin Kang, Shishi Jiang, Jun Min, Fan Hu, Renshi Xu
doi : 10.18632/aging.205351
Analysis of cancer-associated fibroblasts in cervical cancer by single-cell RNA sequencing
Shuang Wen, Xuefeng Lv, Pengxiang Li, Jinpeng Li, Dongchun Qin
doi : 10.18632/aging.205353
Clinical and therapeutical significances of the cluster and signature based on oxidative stress for osteosarcoma
doi : 10.18632/aging.205354
Proteomic analysis reveals the aging-related pathways contribute to pulmonary fibrogenesis
Tingwei Zhang, Xinglong Yuan, Mengqi Jiang, Bo Liu, Nailiang Zhai, Qian Zhang, Xiaodong Song, Changjun Lv, Jinjin Zhang, Hongbo Li
doi : 10.18632/aging.205355
Integrated analysis reveals the potential of cluster of differentiation 86 as a key biomarker in high-grade glioma
Xuebin Wen, Chaochao Wang, Zhihao Pan, Yao Jin, Hongcai Wang, Jiang Zhou, Chengfeng Sun, Gengfan Ye, Maosong Chen
doi : 10.18632/aging.205359
Clinical value of SLC12A9 for diagnosis and prognosis in colorectal cancer
Wang Du, Guozhi Xia, Liang Chen, Lingjun Geng, Rubin Xu, Qingqing Han, Xiaomei Ying, Hongzhu Yu
doi : 10.18632/aging.205360
Unravelling diagnostic clusters and immune landscapes of disulfidptosis patterns in gastric cancer through bioinformatic assay
Peng Zhang, Zhuofeng Chen, Xiaocheng Lin, Siyao Yu, Xiang Yu, Zhuoqun Chen
doi : 10.18632/aging.205365
Identification and validation of key biomarkers associated with macrophages in nonalcoholic fatty liver disease based on hdWGCNA and machine learning
Ruowen Li, Mingjian Zhao, Chengxu Miao, Xiaojia Shi, Jinghui Lu
doi : 10.18632/aging.205374
Efficacy and safety analysis of a HER2-targeting antibody-drug conjugate combined with immune checkpoint inhibitors in solid tumors: a real-world study
Yi-Xin Zhou, Jia-Ling Wang, Xiao-Li Mu, Ya-Juan Zhu, Ye Chen, Ji-Yan Liu
doi : 10.18632/aging.205382
Identification and characterization of extrachromosomal circular DNA in age-related osteoporosis
Qingrun Zhu, Rudong Chen, Mingjie Kuang, Wen Zhang, Dachuan Wang, Shijie Han
doi : 10.18632/aging.205388
Comprehensively prognostic and immunological analysis of VRK Serine/Threonine Kinase 1 in pan-cancer and identification in hepatocellular carcinoma
Dongxing Chen, Wuhan Zhou, Jiafei Chen, Jingui Wang
doi : 10.18632/aging.205389
M-CSF secreted by gastric cancer cells exacerbates the progression of gastric cancer by increasing the expression of SHP2 in tumor-associated macrophages
Shaohua Zhang, Dongfei Ren, Huiyu Hou, Li Yao, Hufang Yuan
doi : 10.18632/aging.205390
Potential impact of cuproptosis-related genes on tumor immunity in esophageal carcinoma
Pengfei Guo, Zemiao Niu, Dengfeng Zhang, Fangchao Zhao, Jing Li, Tianxing Lu, Xuebo Qin, Shiquan Liu, Zhirong Li, Yishuai Li, Shujun Li
doi : 10.18632/aging.205391
Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation
Awaguli Dawuti, Lisha Ma, Xueyan An, Jiawei Guan, Changdong Zhou, Linyun He, Yue Xu, Bo Han, Abudumijiti Abulizi
doi : 10.18632/aging.205416
Development of a prognostic model for glioblastoma multiforme based on the expression levels of efferocytosis-related genes
Wenzhe Xu, Lihui Han, Pengfei Zhu, Yufeng Cheng, Xuan Chen
doi : 10.18632/aging.205422
Unravelling diagnostic clusters and immune landscapes of cuproptosis patterns in intervertebral disc degeneration through dry and wet experiments
Peng Zhang, Jiahui He, Yanchi Gan, Qi Shang, Honglin Chen, Wenhua Zhao, Jianchao Cui, Gengyang Shen, Yuwei Li, Xiaobing Jiang, Guangye Zhu, Hui Ren
doi : 10.18632/aging.205449
A regulatory circuit of lncRNA NLGN1-AS1 and Wnt signalling controls clear cell renal cell carcinoma phenotypes through FZD4-modulated pathways
Haifeng Gao, Wei Chen, Gaojian Pan, Hui Liu, Jinke Qian, Weijun Tang, Wei Wang, Shilei Qian
doi : 10.18632/aging.204263
Protective effect of fluoxetine against oxidative stress induced by renal ischemia-reperfusion injury via the regulation of miR-450b-5p/Nrf2 axis
Zhiqiang Qin, Hao Wang, Quanliang Dou, Luwei Xu, Zheng Xu, Ruipeng Jia
doi : 10.18632/aging.204289
Placenta autophagy is closely associated with preeclampsia
Chaomei Li, Wei Liu, Qunxiu Lao, Haiying Lu, Yingting Zhao
doi : 10.18632/aging.204436
Novel insights into the regulatory role of N6-methyladenosine methylation modified autophagy in sepsis
Cheng-Fei Bi, Jia Liu, Xiao-Dong Hu, Li-Shan Yang, Jun-Fei Zhang
doi : 10.18632/aging.205312
Correction for: Using ESTIMATE algorithm to establish an 8-mRNA signature prognosis prediction system and identify immunocyte infiltration-related genes in Pancreatic adenocarcinoma
Zibo Meng, Dianyun Ren, Kun Zhang, Jingyuan Zhao, Xin Jin, Heshui Wu
doi : 10.18632/aging.205456
Correction for: Sonic hedgehog signaling promotes angiogenesis of endothelial progenitor cells to improve pressure ulcers healing by PI3K/AKT/eNOS signaling
Jianhua Wang, Hongyan Zhan, Mingming Wang, Hua Song, Jianhua Sun, Gang Zhao
doi : 10.18632/aging.205458
