K. Dewilde, Y. Groszmann, D. Van Schoubroeck, K. Grewal, J. Huirne, R. de Leeuw, T. Bourne, D. Timmerman, T. Van den Bosch
doi : 10.1002/uog.27476
E. Preuss, A. De Porto, I. Zisman, H. Bason, O. Ron-Tal, J. Tovbin, E. Barzilay
doi : 10.1002/uog.26314
To determine whether visual biofeedback can be used during labor as an effective tool for shortening the second stage of labor and reducing the need for instrumental delivery.
N. Shreeve, C. Sproule, K. W. Choy, Z. Dong, K. Gajewska-Knapik, M. D. Kilby, F. Mone
doi : 10.1002/uog.27491
First, to determine the incremental yield of whole-genome sequencing (WGS) over quantitative fluorescence polymerase chain reaction (QF-PCR)/chromosomal microarray analysis (CMA) with and without exome sequencing (ES) in fetuses, neonates and infants with a congenital anomaly that was or could have been detected on prenatal ultrasound. Second, to evaluate the turnaround time (TAT) and quantity of DNA required for testing using these pathways.
M. Pozzoni, C. Sammaria, R. Villanacci, C. Borgese, F. Ghisleri, A. Farina, M. Candiani, P. I. Cavoretto
doi : 10.1002/uog.26315
Type-III vasa previa (VP) is a rare form of VP, not necessarily associated with other placental or vascular anomalies, in which aberrant vessels run from the placenta to the amniotic membranes, near the internal cervical os, before returning to the placenta. Early diagnosis of Type-III VP is important but technically challenging. The objective of this study was to gather the current available evidence on the perinatal diagnosis and outcome of Type-III VP.
K. Gadsbøll, I. Vogel, L. H. Pedersen, S. E. Kristensen, E. H. Steffensen, A. Wright, D. Wright, J. Hyett, O. B. Petersen, The Danish Cytogenetic Central Registry study group
doi : 10.1002/uog.27466
To examine the distribution of nuchal translucency thickness (NT), free β-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) in pregnancies with a fetal 22q11.2 aberration. Furthermore, the performance of combined first-trimester screening (cFTS) and a new risk algorithm targeting 22q11.2 deletions in detecting affected pregnancies was evaluated. Finally, prenatal malformations and pregnancy outcome were assessed.
C. Athalye, A. van Nisselrooij, S. Rizvi, M. C. Haak, A. J. Moon-Grady, R. Arnaout
doi : 10.1002/uog.27503
Despite nearly universal prenatal ultrasound screening programs, congenital heart defects (CHD) are still missed, which may result in severe morbidity or even death. Deep machine learning (DL) can automate image recognition from ultrasound.
L. Trigo, R. H. Chmait, A. Llanes, G. Catissi, E. Eixarch, A. Van Speybroeck, D. A. Lapa
doi : 10.1002/uog.27536
To determine if the lower-extremity neurological motor function level in fetuses with open spina bifida deteriorates within the 4-week interval between a first prenatal motor assessment at around 22 weeks of gestation and a second evaluation, prior to ‘late’ prenatal surgery, defined as surgery at 26–28 weeks and, in certain situations, up to 30 weeks, and to assess the association between prenatal presurgical motor-function level, anatomical level of the lesion and postnatal motor-function level.
M. Sanz Cortes, R. M. Johnson, H. Sangi-Haghpeykar, I. Bedei, L. Greenwood, A. A. Nassr, R. Donepudi, W. Whitehead, M. Belfort, A. R. Mehollin-Ray
doi : 10.1002/uog.27480
In-utero repair of an open neural tube defect (ONTD) reduces the risk of developing severe hydrocephalus postnatally. Perforation of the cavum septi pellucidi (CSP) may reflect increased intraventricular pressure in the fetal brain. We sought to evaluate the association of perforated CSP visualized on fetal imaging before and/or after in-utero ONTD repair with the eventual need for hydrocephalus treatment by 1 year of age.
M. M. Gil, D. Cuenca-Gómez, V. Rolle, M. Pertegal, C. DÃÂaz, R. Revello, B. Adiego, M. Mendoza, F. S. Molina, B. Santacruz, Z. Ansbacher-Feldman, H. Meiri, R. Martin-Alonso, Y. Louzoun, C. De Paco Matallana
doi : 10.1002/uog.27478
Effective first-trimester screening for pre-eclampsia (PE) can be achieved using a competing-risks model that combines risk factors from the maternal history with multiples of the median (MoM) values of biomarkers. A new model using artificial intelligence through machine-learning methods has been shown to achieve similar screening performance without the need for conversion of raw data of biomarkers into MoM. This study aimed to investigate whether this model can be used across populations without specific adaptations.
A. Ridder, J. O'Driscoll, A. Khalil, B. Thilaganathan
doi : 10.1002/uog.26306
Pre-eclampsia (PE) is a pregnancy complication associated with premature cardiovascular disease morbidity and mortality (i.e. before 60 years of age or in the first year postpartum). PE is associated with adverse left ventricular (LV) remodeling in the peri- and postpartum periods, an independent risk factor for cardiovascular disease. This study aimed to compare LV geometry by LV mass (LVM) and LVM index (LVMI) between participants with a high vs low screening risk for preterm PE in the first trimester.
V. Souter, I. Painter, K. Sitcov, A. Khalil
doi : 10.1002/uog.27472
Low-dose aspirin (LDA) has been shown to reduce the risk of preterm pre-eclampsia and it has been suggested that it should be recommended for all pregnancies. However, some studies have reported an association between LDA and an increased risk of bleeding complications in pregnancy. Our aim was to evaluate the risk of placental abruption and postpartum hemorrhage (PPH) in patients for whom their healthcare provider had recommended prophylactic aspirin.
N. Sokratous, A. Wright, A. Syngelaki, E. Kakouri, A. Laich, K. H. Nicolaides
doi : 10.1002/uog.27481
First, to examine the predictive performance of maternal serum glycosylated fibronectin (GlyFn) at 35 + 0 to 36 + 6 weeks' gestation in screening for delivery with pre-eclampsia (PE) and delivery with gestational hypertension (GH) at ≥ 37 weeks' gestation, both within 3 weeks and at any time after the examination.
K. Robertson, M. Vieira, L. Impey
doi : 10.1002/uog.26305
F. Bailey, J. Gaughran, S. Mitchell, C. Ovadia, T. K. Holland
doi : 10.1002/uog.27529
Around 80% of women with endometriosis have superficial endometriosis (SE) rather than ovarian or deep endometriosis (DE). However, to date, advances in non-invasive, imaging-based diagnosis have been limited to DE or ovarian disease. The objective of this study was to determine whether we can detect SE on transvaginal ultrasound scan (TVS) by assessing the peritoneum of the pouch of Douglas (POD).
C. Gine, N. Maiz, S. Arévalo, C. Rodó, M. López, E. Carreras
doi : 10.1002/uog.27457
R. Corroenne, M. Jacquier, J. Stirnemann, L. J. Salomon, Y. Ville, G. Chalouhi
doi : 10.1002/uog.26295
J. Morales-Roselló, A. MartÃnez-Varea
doi : 10.1002/uog.27468
G. R. DeVore
doi : 10.1002/uog.27479
F. D'Antonio, D. Di Mascio, I. Mappa, G. Rizzo
doi : 10.1002/uog.27545
R. Corroenne, H. Mahallati, D. Grevent, L. J. Salomon
doi : 10.1002/uog.27553
A. Youssef, B. Nedu, F. Dapoto, E. Brunelli
doi : 10.1002/uog.27556
A. Khalil, A. Sotiriadis, F. D'Antonio, F. Da Silva Costa, A. Odibo, F. Prefumo, A. T. Papageorghiou, L. J. Salomon
doi : 10.1002/uog.27538
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