Nature Reviews Rheumatology




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سفارش

Biopsy-driven trial a milestone towards precision medicine in RA

Sarah Onuora

doi : 10.1038/s41584-021-00599-x

Volume 17, Issue 4, April 2021, Published 10 March 2021

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Antidepressant identified as potential DMOAD

Jessica McHugh

doi : 10.1038/s41584-021-00594-2

Volume 17, Issue 4, April 2021, Published 04 March 2021

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RA remission attainable during pregnancy

Jessica McHugh

doi : 10.1038/s41584-021-00595-1

Volume 17, Issue 4, April 2021, Published 04 March 2021

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2019 EULAR–ACR classification criteria for SLE performs well in children

Jessica McHugh

doi : 10.1038/s41584-021-00596-0

Volume 17, Issue 4, April 2021, Published 05 March 2021

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Tocilizumab prevents ILD progression in early SSc

Jessica McHugh

doi : 10.1038/s41584-021-00597-z

Volume 17, Issue 4, April 2021, Published 05 March 2021

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Different phenotypes identified for Behçet syndrome

Jessica McHugh

doi : 10.1038/s41584-021-00587-1

Volume 17, Issue 4, April 2021, Published 22 February 2021

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Cigarette smoke exacerbates joint damage via miR-132

Joanna Clarke

doi : 10.1038/s41584-021-00586-2

Volume 17, Issue 4, April 2021, Published 15 February 2021

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Targeting pDCs in SSc

Sarah Onuora

doi : 10.1038/s41584-021-00598-y

Volume 17, Issue 4, April 2021, Published 08 March 2021

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How do dietary interventions affect serum urate and gout?

Sarah L. Morgan & Jasvinder A. Singh

doi : 10.1038/s41584-021-00576-4

Volume 17, Issue 4, April 2021, Published 28 January 2021

An important question for patients and providers is whether and to what extent dietary interventions, diet supplements or weight loss can help to prevent incident gout or manage existing gout. Evidence is emerging, but randomized trials are still needed to fill this important knowledge gap.

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Moving towards a molecular categorization of autoimmune disease

Michael L. Whitfield

doi : 10.1038/s41584-021-00589-z

Volume 17, Issue 4, April 2021, Published 02 March 2021

The field of rheumatology is poised to categorize the phenotypes of systemic autoimmune diseases on the basis of measurable and quantifiable molecular signatures. Emerging efforts to identify similarities across diseases, predict clinical outcomes and predict response to therapy using quantitative, data-driven approaches could considerably change treatment paradigms.

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Location, location, location: how the tissue microenvironment affects inflammation in RA

Christopher D. Buckley, Caroline Ospelt, Steffen Gay & Kim S. Midwood

doi : 10.1038/s41584-020-00570-2

Volume 17, Issue 4, April 2021, Published 01 February 2021

Tissues are composed of cells and an extracellular matrix. In this Review, the authors discuss how a greater understanding of the role of the synovial extracellular matrix in rheumatoid arthritis could lead to improved disease diagnosis and new therapies.

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TNF in the era of immune checkpoint inhibitors: friend or foe?

Allen Y. Chen, Jedd D. Wolchok & Anne R. Bass

doi : 10.1038/s41584-021-00584-4

Volume 17, Issue 4, April 2021, Published 08 March 2021

TNF inhibitors are used to treat various immune-related adverse events caused by immune checkpoint inhibitors (ICIs). However, whether TNF inhibition compromises the anticancer efficacy of ICI therapy is unknown. This Review discusses the relationship between TNF, TNF inhibition and cancer.

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The gut–joint axis in rheumatoid arthritis

Mario M. Zaiss, Hsin-Jung Joyce Wu, Daniele Mauro, Georg Schett & Francesco Ciccia

doi : 10.1038/s41584-021-00585-3

Volume 17, Issue 4, April 2021, Published 05 March 2021

Intestinal dysbiosis is thought to be involved in the early stages of rheumatoid arthritis (RA). In this Review, the authors discuss the gut–joint axis in RA and the potentially pathogenic role of gut-derived immune cells in the joints.

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Consensus terminology for preclinical phases of psoriatic arthritis for use in research studies: results from a Delphi consensus study

Lourdes M. Perez-Chada, Rebecca H. Haberman, Vinod Chandran, Cheryl F. Rosen, Christopher Ritchlin, Lihi Eder, Philip Mease, Soumya Reddy, Alexis Ogdie, Joseph F. Merola & Jose U. Scher

doi : 10.1038/s41584-021-00578-2

Volume 17, Issue 4, April 2021, Published 15 February 2021

In this Consensus Statement, an expert panel from the Psoriasis and Psoriatic Arthritis Clinics Multicenter Advancement Network (PPACMAN) recommends terminology for defining specific subgroups of individuals during the preclinical and early clinical phases of psoriatic arthritis to be used in research studies.

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Diagnostic role of anti-dsDNA antibodies: do not forget autoimmune hepatitis

Alessandro Granito, Luigi Muratori, Francesco Tovoli & Paolo Muratori

doi : 10.1038/s41584-021-00573-7

Volume 17, Issue 4, April 2021, Published 18 January 2021

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Reply to: Diagnostic role of anti-dsDNA antibodies: do not forget autoimmune hepatitis

David S. Pisetsky & Peter E. Lipsky

doi : 10.1038/s41584-021-00574-6

Volume 17, Issue 4, April 2021, Published 18 January 2021

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Author Correction: Raynaud phenomenon and digital ulcers in systemic sclerosis

Michael Hughes, Yannick Allanore, Lorinda Chung, John D. Pauling, Christopher P. Denton & Marco Matucci-Cerinic

doi : 10.1038/s41584-021-00591-5

Volume 17, Issue 4, April 2021, Published 09 March 2021

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Author Correction: Location, location, location: how the tissue microenvironment affects inflammation in RA

Christopher D. Buckley, Caroline Ospelt, Steffen Gay & Kim S. Midwood

doi : 10.1038/s41584-021-00602-5

Volume 17, Issue 4, April 2021, Published 12 March 2021

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