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Prognostic significance of senescence-related tumor microenvironment genes in head and neck squamous cell carcinoma
Young Chan Lee, Yonghyun Nam, Minjeong Kim, Su Il Kim, Jung-Woo Lee, Young-Gyu Eun, Dokyoon Kim
doi : 10.18632/aging.205346
Volume 16, Issue 2
Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation
Emily M. Bertucci-Richter, Ethan P. Shealy, Benjamin B. Parrott
doi : 10.18632/aging.205503
Potential prognosis and immunotherapy predictor TFAP2A in pan-cancer
Chenxi Niu, Haixuan Wen, Shutong Wang, Guang Shu, Maonan Wang, Hanxi Yi, Ke Guo, Qiong Pan, Gang Yin
doi : 10.18632/aging.205225
Prediction significance of autophagy-related genes in survival probability and drug resistance in diffuse large B-cell lymphoma
Dan Xiong, Xiaolei Wei, Weiming Huang, Jingxia Zheng, Ru Feng
doi : 10.18632/aging.205282
Establishing the role of BRCA1 in the diagnosis, prognosis and immune infiltrates of breast invasive cancer by bioinformatics analysis and experimental validation
Leilei Li, Shuangyan Li, Xuyang Zhang, Liying Mei, Xueqin Fu, Min Dai, Na Wei
doi : 10.18632/aging.205366
TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage
Keke Zhang, Zhen Qin, Jinyan Chen, Gengyin Guo, Xiaokun Jiang, Feng Wang, Jianfeng Zhuang, Zhen Zhang
doi : 10.18632/aging.205379
AMIGO2 is a pivotal therapeutic target related to M2 polarization of macrophages in pancreatic ductal adenocarcinoma
Shensi Chen, Wujun Du, Ke Feng, Ke Liu, Cunji Li, Shengming Li, Hua Yin
doi : 10.18632/aging.205380
An enriched environment ameliorates maternal sleep deprivation-induced cognitive impairment in aged mice by improving mitochondrial function via the Sirt1/PGC-1α pathway
Ru-Meng Wei, Yue-Ming Zhang, Kai-Xuan Zhang, Gao-Xia Liu, Xue-Yan Li, Jing-Ya Zhang, Wei-Zhong Lun, Xue-Chun Liu, Gui-Hai Chen
doi : 10.18632/aging.205385
Sesamin-mediated high expression of BECN2 ameliorates cartilage endplate degeneration by reducing autophagy and inflammation
Baining Zhang, Zhiwei He, Jialin Guo, Feng Li, Zhi Huang, Wenkai Zheng, Wenhua Xing, Manglai Li, Yong Zhu, Xuejun Yang
doi : 10.18632/aging.205386
A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion
Wan-Rong Jiang, Yong-Ming Zhou, Wei Wu, Li-Jie Yang, You Wu, Xin-Yuan Zhang, Zhao-Hui Yao
doi : 10.18632/aging.205387
Myeloid-specific knockout of Notch-1 inhibits MyD88- and TRIF-mediated TLR signaling pathways by regulating oxidative stress-SHP2 axis, thus restraining aneurysm progression
Yu Li, Ailin Guo, Jianlei Liu, Lijuan Tang, Lide Su, Zonghong Liu
doi : 10.18632/aging.205392
Gut microbial community and fecal metabolomic signatures in different types of osteoporosis animal models
Xiaochen Qiao, Xiaoyan Li, Zhichao Wang, Yi Feng, Xiaochun Wei, Lu Li, Yongchun Pan, Kun Zhang, Ruhao Zhou, Lei Yan, Pengcui Li, Chaojian Xu, Zhi Lv, Zhi Tian
doi : 10.18632/aging.205396
Development and validation of a combined cuproptosis and immunogenic cell death prognostic model for diffuse large B-cell lymphoma
Nana Wang, Shanshan Shi, Moran Li, Xiaoning Yu, Guangxin Ma
doi : 10.18632/aging.205399
Silencing of METTL3 prevents the proliferation, migration, epithelial-mesenchymal transition, and renal fibrosis of high glucose-induced HK2 cells by mediating WISP1 in m6A-dependent manner
Yuanzhen Chen, Ping Li, Mei Lin, Ying Jiang, Guiping Tan, Lianfang Huang, Dan Song
doi : 10.18632/aging.205401
Disulfidptosis status influences prognosis and therapeutic response in clear cell renal cell carcinoma
Weiming Deng, Zhenwei Xie, Libo Chen, Wenjin Li, Mingyong Li
doi : 10.18632/aging.205405
Molecular subgroup establishment and signature creation of lncRNAs associated with acetylation in lung adenocarcinoma
Hao Chen, Yuanyong Wang, Changjian Shao, Kai Guo, Guanglin Liu, Zhaoyang Wang, Hongtao Duan, Minghong Pan, Peng Ding, Yimeng Zhang, Jing Han, Xiaolong Yan
doi : 10.18632/aging.205407
α-Hederin promotes ferroptosis and reverses cisplatin chemoresistance in non-small cell lung cancer
Shugao Han, Xi Yang, Jing Zhuang, Qing Zhou, Jingjing Wang, Lixin Ru, Furong Niu, Wei Mao
doi : 10.18632/aging.205408
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1
Dandan Yi, Zetian Wang, Haojie Yang, Ru Wang, Xianbiao Shi, Zhijian Liu, Fazhan Xu, Qing Lu, Xiao Chu, Jianfeng Sang
doi : 10.18632/aging.205419
Cisplatin and doxorubicin chemotherapy alters gut microbiota in a murine osteosarcoma model
Zhi Tian, Xiaochen Qiao, Zhichao Wang, Xiaoyan Li, Yongchun Pan, Xiaochun Wei, Zhi Lv, Pengcui Li, Qiujing Du, Wenhao Wei, Lei Yan, Song Chen, Chaojian Xu, Yi Feng, Ruhao Zhou
doi : 10.18632/aging.205428
MicroRNA-141-3p reduces pulmonary hypoxia/reoxygenation injury through suppression of Beclin-1-dependent autophagy
Yanping Zhan, Lei Li, Chen Guo, Yang Zhang, Lili Zhao, Zhe Tao, Hua Zhang, Shibiao Chen
doi : 10.18632/aging.205430
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis
Shunling Yuan, Yirong Wang, Jialun Yang, Yingzhe Tang, Weijia Wu, Xiangyuan Meng, Ye Jian, Yong Lei, Yang Liu, Changfa Tang, Zhe Zhao, Fei Zhao, Wenfeng Liu
doi : 10.18632/aging.205432
Ganodermanontriol regulates tumor-associated M2 macrophage polarization in gastric cancer
Likang Zhang, Pinghui Shi, Peng Jin, Zhenwei Chen, Biwen Hu, Chenxi Cao, Xiaoguang Wang, Jian Sheng
doi : 10.18632/aging.205434
Identification of CD8+ T cell-related biomarkers and immune infiltration characteristic of rheumatoid arthritis
Qizun Wang, Qianqian Li, Ronghuan Wang, Yanning Li, Jie Wang, Zhu Guo, Feng Li, Bohua Chen, Hongfei Xiang, Tianrui Wang, Xiaolin Wu
doi : 10.18632/aging.205435
Combination of bulk RNA sequencing and scRNA sequencing uncover the molecular characteristics of MAPK signaling in kidney renal clear cell carcinoma
Xiunan Li, Hewen Guan, Chuanyu Ma, Yunfei Dai, Ji Su, Xu Chen, Qihang Yuan, Jianbo Wang
doi : 10.18632/aging.205436
Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features
Tianbing Wang, Kai Guo, Shoushan Yang, Di Zhang, Haodong Cui, Jimin Yin, Shuhui Yuan, Yong Wang, Yong Qi, Wenyong Wu
doi : 10.18632/aging.205438
Identification and validation of anoikis-related lncRNAs for prognostic significance and immune microenvironment characterization in ovarian cancer
Lixue Cao, Shaofen Zhang, Haojie Peng, Yongqing Lin, Zhihui Xi, Wumei Lin, Jialing Guo, Geyan Wu, Fei Yu, Hui Zhang, Haiyan Ye
doi : 10.18632/aging.205439
LRP6 is a potential biomarker of kidney clear cell carcinoma related to prognosis and immune infiltration
Liqun Lu, Yan Lei, Yanling Li, Lujuan Wang
doi : 10.18632/aging.205440
The miR-146b-3p/TNFAIP2 axis regulates cell differentiation in acute myeloid leukaemia
Gaochen Lan, Xiaolong Wu, Aiyue Zhao, Jinjian Lan, Qiusheng Guo, Bolin Wang, Fenglin Shen, Xiaoling Yu, Yanna Zhao, Ruilan Gao, Tianwen Xu
doi : 10.18632/aging.205441
Molecular map of cGAS-STING pathway-related genes in bladder cancer: the perspective toward immune microenvironment and prognosis
Dong Wei, Ying Liu, Ying Yuan, Yishuai Li, Fangchao Zhao, Xuebo Qin
doi : 10.18632/aging.205442
Prognostic characteristics of a six-gene signature based on ssGSEA in sarcoma
Jun Liu, Jianjun Lu, Gefei Wang, Liming Gu, Wenli Li
doi : 10.18632/aging.205443
Joint analysis of proteome, transcriptome, and multi-trait analysis to identify novel Parkinson’s disease risk genes
Jing-Jing Shi, Cheng-Yuan Mao, Ya-Zhou Guo, Yu Fan, Xiao-Yan Hao, Shuang-Jie Li, Jie Tian, Zheng-Wei Hu, Meng-Jie Li, Jia-Di Li, Dong-Rui Ma, Meng-Nan Guo, Chun-Yan Zuo, Yuan-Yuan Liang, Yu-Ming Xu, Jian Yang, Chang-He Shi
doi : 10.18632/aging.205444
Identification of a basement membrane gene signature for predicting prognosis and estimating the tumor immune microenvironment in prostate cancer
Tao Xie, Du-Jiang Fu, Kang-Jing Li, Jia-Ding Guo, Zhao-Ming Xiao, Zhijie Li, Shan-Chao Zhao
doi : 10.18632/aging.205445
SLC7A8 overexpression inhibits the growth and metastasis of lung adenocarcinoma and is correlated with a dismal prognosis
Fang-Ming Wang, Li-Qiang Xu, Zhong-Chao Zhang, Qiang Guo, Zhi-Peng Du, Yue Lei, Xu Han, Chuang-Yan Wu, Feng Zhao, Jiu-Ling Chen
doi : 10.18632/aging.205446
PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance
Shiue-Wei Lai, Yi-Chiao Cheng, Kee-Thai Kiu, Min-Hsuan Yen, Ying-Wei Chen, Vijesh Kumar Yadav, Chi-Tai Yeh, Kuang-Tai Kuo, Tung-Cheng Chang
doi : 10.18632/aging.205447
FABP6 serves as a new therapeutic target in esophageal tumor
Dengfeng Zhang, Fangchao Zhao, Haitao Liu, Pengfei Guo, Zhirong Li, Shujun Li
doi : 10.18632/aging.205448
Usenamine A triggers NLRP3/caspase-1/GSDMD-mediated pyroptosis in lung adenocarcinoma by targeting the DDX3X/SQSTM1 axis
Min Li, Rongrong Wu, Le Wang, Dongyi Zhu, Shinan Liu, Ruolan Wang, Chaowen Deng, Shenglin Zhang, Min Chen, Ruojin Lu, Hongxing Zhu, Mengting Mo, Xiaoqiong He, Zhuang Luo
doi : 10.18632/aging.205450
Trends in suicide mortality among cancer survivors in the US, 1975-2020
Hao Wan, Ru Chen, Xiangpeng Zhan, Luyao Chen, Zhongyuan Li
doi : 10.18632/aging.205451
Therapeutic strategies and predictive models for Xp11.2 translocation/TFE3 gene fusion renal cell carcinoma in adults based on data of two Chinese medical centers
Yunkai Yang, Changfeng Zhao, Zhida Wang, Feng Liu, Ming Zhao, Huiwen Yang, Jun Chen, Xuejing Chen, Min Shi, Dixing Jiang, Xiaoting Luo, Yue Duan, Yuchen Bai
doi : 10.18632/aging.205452
Malignant cell receptor-ligand subtypes guide the prediction of prognosis and personalized immunotherapy of liver cancer
Junzheng Wu, Chuncheng Wu, Xianhui Cai, Peipei Li, Jianjun Lin, Fuqiang Wang
doi : 10.18632/aging.205453
Identification and validation of methylation-CpG prognostic signature for prognosis of hepatocellular carcinoma
Chunmei He, Zehao Guo, Hao Zhang, Ganqing Yang, Jintao Gao, Zhijing Mo
doi : 10.18632/aging.205454
Development and validation of glycosyltransferase related-gene for the diagnosis and prognosis of head and neck squamous cell carcinoma
Miao He, Li Wang, Zihan Yue, Chunbo Feng, Guosheng Dai, Jinsong Jiang, Hui Huang, Qingjun Ji, Minglang Zhou, Dapeng Li, Wei Chai
doi : 10.18632/aging.205455
Tremella fuciformis polysaccharides induce ferroptosis in Epstein–Barr virus-associated gastric cancer by inactivating NRF2/HO-1 signaling
Wencheng Kong, Xinchun Liu, Hangzhang Zhu, Sixing Zheng, Guang Yin, Panpan Yu, Yuqiang Shan, Shenglin Ma, Rongchao Ying, Huicheng Jin
doi : 10.18632/aging.205457
Identification of key ferroptosis genes and mechanisms associated with breast cancer using bioinformatics, machine learning, and experimental validation
Shuang Liang, Yan-Ming Bai, Bo Zhou
doi : 10.18632/aging.205459
Circ0060467 sponges miR-6805 to promote hepatocellular carcinoma progression through regulating AIFM2 and GPX4 expression
Ye-Ru Tan, Bao-Hong Jiang, Wen-Jie Feng, Zhi-Long He, Yi-Ling Jiang, Yi Xun, Xiao-Ping Wu, Yue-Hua Li, Hong-Bo Zhu
doi : 10.18632/aging.205460
Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments
Yuanmin Xu, Xu Wang, Weiwei Yuan, Ling Zhang, Wei Chen, Kongwang Hu
doi : 10.18632/aging.205461
IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts
Kun-Tsan Lee, Chih-Yang Lin, Shan-Chi Liu, Xiu-Yuan He, Chun-Hao Tsai, Chih-Yuan Ko, Yuan-Hsin Tsai, Chia-Chia Chao, Po-Chun Chen, Chih-Hsin Tang
doi : 10.18632/aging.205462
Activation of Notch-1 signaling pathway in macrophages to secrete PD-L1 and regulate cytotoxicity of CAR-T cells in diffuse large B-cell lymphoma
Weijing Li, Lili Wu, Chen Huang, Hongqing Ma, Lianjing Wang, Wei Liu, Lihong Liu
doi : 10.18632/aging.205463
The integration of multi-omics analysis and machine learning for the identification of prognostic assessment and immunotherapy efficacy through aging-associated genes in lung cancer
Wei Lu, Yun Zhou, Ruixuan Zhao, Qiushi Liu, Wei Yang, Tianyi Zhu
doi : 10.18632/aging.205464
CDK16 as a potential prognostic biomarker correlated with an immunosuppressive tumor microenvironment and benefits in enhancing the effectiveness of immunotherapy in human cancers
Juntao Qi, Gujie Wu, Min He, You Xu, Zheng Yang, Liang Ding, Yan Wang, Zhi Zhang
doi : 10.18632/aging.205465
Knockdown of RNA-binding protein IMP3 suppresses oral squamous cell carcinoma proliferation by destabilizing E2F5 transcript
Zhenzhen Wang, Huahua Zhang, Fang Li, Chen Huang
doi : 10.18632/aging.205466
Investigation of Tongxie-Yaofang formula in treating ulcerative colitis based on network pharmacology via regulating MAPK/AKT signaling pathway
Xinhong Liu, Mao Ye, Yinglin He, Qin Lai, Bo Liu, Leichang Zhang
doi : 10.18632/aging.205467
Melatonin improves stroke through MDM2-mediated ubiquitination of ACSL4
Qing Ji, Le Zhang, Hui Ye
doi : 10.18632/aging.205469
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer
Zhenpeng Lian, Pei Tian, Shenfei Ma, Taihao Chang, Ranlu Liu, Qingchuan Feng, Jing Li
doi : 10.18632/aging.205472
Consistency of mouse models with human intracerebral hemorrhage: core targets and non-coding RNA regulatory axis
Sinan Jin, Jincheng Meng, Chong Zhang, Jiping Qi, He Wu
doi : 10.18632/aging.205473
The role of miR-6884-5p in epithelial-mesenchymal transition in non-small cell lung cancer
Lianyong Zhang, Wei Chi, Xue Wang, Jingjing Li, Fei Li, Yuxia Ma, Qianyun Zhang
doi : 10.18632/aging.205474
Correction for: Xuesaitong promotes myocardial angiogenesis in myocardial infarction mice by inhibiting MiR-3158-3p targeting Nur77
Jiangquan Liao, Mingjing Shao, Yan Wang, Peng Yang, Dongliang Fu, Mengru Liu, Tong Gao, Kangkang Wei, Xianlun Li, Jinhang Du
doi : 10.18632/aging.205576
Retraction: MiR-27a promotes the autophagy and apoptosis of IL-1β treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling
Chen Cai, Shaoxiong Min, Bo Yan, Wen Liu, Xiao Yang, Liuxun Li, Ting Wang, Anmin Jin
doi : 10.18632/aging.204906
