دسترسی یکساله به بیش از ۵۰۰ ژورنال روز جهان موجود در سامانه
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Effect of Canakinumab vs Placebo on Survival Without Invasive Mechanical Ventilation in Patients Hospitalized With Severe COVID-19
Roberto Caricchio, MD1; Antonio Abbate, MD, PhD2; Ivan Gordeev, PhD3; Jamie Meng, MD, PhD4; Priscilla Y Hsue, MD5; Tuhina Neogi, MD, PhD6; Roberto Arduino, MD7; Daria Fomina, MD8,9; Roman Bogdanov, MD10; Tatiana Stepanenko, MD11; Pilar Ruiz-Seco, MD12; Andrés G?nzalez-Garc?a, MD, PhD13; Yu Chen, MSc14; Yuhan Li, MSc14; Sarah Whelan, BSc, MSc15; Stephanie Noviello, MD, MPH14; for the CAN-COVID Investigators
doi : 10.1001/jama.2021.9508
JAMA. 2021;326(3):230-239
Effective treatments for patients with severe COVID-19 are needed.
Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA)
Jeffry Florian, PhD1; Murali K. Matta, PhD1; Ryan DePalma, PhD1; Victoria Gershuny, PhD1; Vikram Patel, PhD1; Cheng-Hui Hsiao, PhD1; Robbert Zusterzeel, MD, PhD, MPH1; Rodney Rouse, PhD, DVM, MBA1; Kristin Prentice, MS1,2; Colleen Gosa Nalepinski, MPAS, PA-C3; Insook Kim, PhD4; Sojeong Yi, PhD4; Liang Zhao, PhD5; Miyoung Yoon, PhD5; Susan Selaya, PhD6; David Keire, PhD6; Joyce Korvick, MD, MPH7; David G. Strauss, MD, PhD1
doi : 10.1001/jama.2021.9199
JAMA. 2021;326(3):240-249
In 2019, the US Food and Drug Administration (FDA) received a citizen petition indicating that ranitidine contained the probable human carcinogen N-nitrosodimethylamine (NDMA). In addition, the petitioner proposed that ranitidine could convert to NDMA in humans; however, this was primarily based on a small clinical study that detected an increase in urinary excretion of NDMA after oral ranitidine consumption.
Medical Debt in the US, 2009-2020
Raymond Kluender, PhD1; Neale Mahoney, PhD2,3; Francis Wong, PhD3; Wesley Yin, PhD3,4
doi : 10.1001/jama.2021.8694
JAMA. 2021;326(3):250-256
Medical debt is an increasing concern in the US, yet there is limited understanding of the amount and distribution of medical debt, and its association with health care policies.
Sperm Parameters Before and After COVID-19 mRNA Vaccination
Daniel C. Gonzalez, BS1; Daniel E. Nassau, MD1; Kajal Khodamoradi, PhD1; Emad Ibrahim, MD1; Ruben Blachman-Braun, MD1; Jesse Ory, MD1; Ranjith Ramasamy, MD1
doi : 10.1001/jama.2021.9976
JAMA. 2021;326(3):273-274
Prescription Drug Monitoring Program Mandates and Opioids Dispensed Following Emergency Department Encounters for Patients With Sickle Cell Disease or Cancer With Bone Metastasis
Hao Zhang, PhD1; Austin S. Kilaru, MD, MSHP2; Zachary F. Meisel, MD, MPH, MSHP2; Yuhua Bao, PhD1
doi : 10.1001/jama.2021.10161
JAMA. 2021;326(3):274-276
Guidelines for Reporting Trial Protocols and Completed Trials Modified Due to the COVID-19 Pandemic and Other Extenuating Circumstances
Aaron M. Orkin, MD, MSc, MPH1,2; Peter J. Gill, MD, DPhil3; Davina Ghersi, MD, PhD4; Lisa Campbell, MD, MBBCh, BSc5; Jeremy Sugarman, MD, MPH, MA6; Richard Emsley, PhD7; Philippe Gabriel Steg, MD8; Charles Weijer, MD, PhD9; John Simes, MBBS, MD10; Tanja Rombey, MPH11; Hywel C. Williams, DSc12,13; Janet Wittes, PhD14; David Moher, PhD15; Dawn P. Richards, PhD16; Yvette Kasamon, MD17; Kenneth Getz, MBA18; Sally Hopewell, MSc, DPhil19; Kay Dickersin, MA, PhD20; Taixiang Wu, MPH21; Ana Patricia Ayala, MISt22; Kenneth F. Schulz, PhD23,24; Sabine Calleja, MI25; Isabelle Boutron, MD, PhD26; Joseph S. Ross, MD, MHS27,28; Robert M. Golub, MD29,30; Karim M. Khan, MD, PhD31; Cindy Mulrow, MD, MSc32; Nandi Siegfried, PhD, MPH33; Joerg Heber, PhD34; Naomi Lee, MD35; Pamela Reed Kearney, MD36; Rhoda K. Wanyenze, MBChB, MPH, PhD37; Asbj?rn Hr?bjartsson, MD, PhD, MPhil38; Rebecca Williams, PharmD, MPH39; Nita Bhandari, PhD40; Peter Jüni, MD41; An-Wen Chan, MD, DPhil42; for the CONSERVE Group
doi : 10.1001/jama.2021.9941
JAMA. 2021;326(3):257-265
Extenuating circumstances can trigger unplanned changes to randomized trials and introduce methodological, ethical, feasibility, and analytical challenges that can potentially compromise the validity of findings. Numerous randomized trials have required changes in response to the COVID-19 pandemic, but guidance for reporting such modifications is incomplete.
Intensive Medical Management to Prevent Large and Small Artery Atherothrombotic Stroke
Meng Lee, MD1; Bruce Ovbiagele, MD, MSc, MAS, MBA2; Jeffrey L. Saver, MD3,4
doi : 10.1001/jama.2021.9917
JAMA. 2021;326(3):217-218
Sharing Technology and Vaccine Doses to Address Global Vaccine Inequity and End the COVID-19 Pandemic
Matthew M. Kavanagh, PhD1,2; Lawrence O. Gostin, JD1; Madhavi Sunder, JD1
doi : 10.1001/jama.2021.10823
JAMA. 2021;326(3):219-220
Ethical Considerations of Offering Benefits to COVID-19 Vaccine Recipients
Govind Persad, JD, PhD1; Ezekiel J. Emanuel, MD, PhD2
doi : 10.1001/jama.2021.11045
JAMA. 2021;326(3):221-222
To Err Is Human, to Apologize Is Hard
Thalia Margalit Krakower, MD1
doi : 10.1001/jama.2021.10840
JAMA. 2021;326(3):223-224
Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation
C. Michael White, PharmD1,2; Adrian V. Hernandez, MD, PhD1,2,3
doi : 10.1001/jama.2021.10043
JAMA. 2021;326(3):225-227
Medical Debt as a Social Determinant of Health
Carlos F. Mendes de Leon, PhD1; Jennifer J. Griggs, MD, MPH2,3
doi : 10.1001/jama.2021.9011
JAMA. 2021;326(3):228-229
Novel Lipid-Lowering Therapies to Reduce Cardiovascular Risk
John T. Wilkins, MD, MS1,2; Donald M. Lloyd-Jones, MD, ScM1,2
doi : 10.1001/jama.2021.2244
JAMA. 2021;326(3):266-267
Challenges of Accuracy in Germline Clinical Sequencing Data
Ryan Poplin, MS1; Justin M. Zook, PhD2; Mark DePristo, PhD3
doi : 10.1001/jama.2021.0407
JAMA. 2021;326(3):268-269
Metoclopramide Nasal Spray (Gimoti) for Diabetic Gastroparesis
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doi : 10.1001/jama.2020.26625
JAMA. 2021;326(3):270-271
Alcohol-Related Diseases Increased as Some People Drank More During the COVID-19 Pandemic
Rita Rubin, MA
doi : 10.1001/jama.2021.10626
JAMA. 2021;326(3):209-211
Another COVID-19 Fallout: Teens’ Happy Hour With Parents
Anita Slomski, MA
doi : 10.1001/jama.2021.11007
JAMA. 2021;326(3):212-213
FDA: Stop Using Medtronic’s Heartware Ventricular Assist Device
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.11386
JAMA. 2021;326(3):215
New Software Can Aid in Early Autism Spectrum Disorder Diagnosis
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.10699
JAMA. 2021;326(3):215
Treatment Approved for “Undruggable” Lung Cancer
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.11387
JAMA. 2021;326(3):215
Antibiotic Use in UK’s COVID-19 Patients Often Unnecessary
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.10458
JAMA. 2021;326(3):214
Urgent Need to Reduce Heart Disease Among Women Worldwide
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.11409
JAMA. 2021;326(3):214
Patients in Afghanistan Face Growing Obstacles to Care
Bridget M. Kuehn, MSJ
doi : 10.1001/jama.2021.11410
JAMA. 2021;326(3):214
Low Back Pain
Adrian C. Traeger, PhD1; Amir Qaseem, MD, PhD, MHA2; James H. McAuley, PhD3
doi : 10.1001/jama.2020.19715
JAMA. 2021;326(3):286
Backstop Price Caps in Commercial Health Care Markets
Jay B. Lusk, BSc1; Ryan C. McDevitt, PhD2
doi : 10.1001/jama.2021.6809
JAMA. 2021;326(3):276-277
Backstop Price Caps in Commercial Health Care Markets—Reply
Michael E. Chernew, PhD1; Maximilian J. Pany, BA2
doi : 10.1001/jama.2021.6812
JAMA. 2021;326(3):277
Strategies to Overcome the Market Dominance of Hospitals
Benjamin S. Kornitzer, MD1
doi : 10.1001/jama.2021.6892
JAMA. 2021;326(3):277-278
Strategies to Overcome the Market Dominance of Hospitals—Reply
Soleil Shah, MSc1; Amol S. Navathe, MD, PhD2; Robert P. Kocher, MD1
doi : 10.1001/jama.2021.6895
JAMA. 2021;326(3):278-279
Addition of Nonauthor Collaborator Names of the WHIST Trial
doi : 10.1001/jama.2021.7433
JAMA. 2021;326(3):279
