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Associate Editorial Board
doi : 10.1016/S0007-0912(21)00250-6
Volume 126, Issue 6, June 2021, Page ii
Heart, home, and frailty: new risk scores and outcomes for cardiac surgery patients
Jai N. Darvall, David A. Story
doi : 10.1016/j.bja.2021.02.022
Volume 126, Issue 6, June 2021, Pages 1081-1084
Anaesthesia, neural activity, and brain development: interneurones in the spotlight
Laszlo Vutskits
doi : 10.1016/j.bja.2021.03.002
Volume 126, Issue 6, June 2021, Pages 1084-1085
Difficult airway management: children are different from adults, and neonates are different from children!
Narasimhan Jagannathan, Takashi Asai
doi : 10.1016/j.bja.2021.03.012
Volume 126, Issue 6, June 2021, Pages 1086-1088
Surgery and opioids: some cracks in an enduring romance
Devjit Srivastava, Paul Wilkinson
doi : 10.1016/j.bja.2021.02.003
Volume 126, Issue 6, June 2021, Pages 1088-1092
Assessing ‘desire for more pain treatment’ reveals much room for improvement after tonsillectomy and appendectomy in children
Mark Alcock, George Chalkiadis
doi : 10.1016/j.bja.2021.02.019
Volume 126, Issue 6, June 2021, Pages 1092-1094
New evidence to inform decisions and guidelines in difficult airway management
Alistair F. McNarry, Takashi Asai
doi : 10.1016/j.bja.2021.03.003
Volume 126, Issue 6, June 2021, Pages 1094-1097
Applying the adverse outcome pathway concept to questions in anaesthetic neurotoxicity
Jennifer Waspe, Timothy J.A. Chico, Tom G. Hansen
doi : 10.1016/j.bja.2021.03.009
Volume 126, Issue 6, June 2021, Pages 1097-1102
Association of frailty with days alive at home after cardiac surgery: a population-based cohort study
Daniel I. McIsaac, Alexandra Fottinger, Ewa Sucha, Bernard McDonald
doi : 10.1016/j.bja.2021.02.011
Volume 126, Issue 6, June 2021, Pages 1103-1110
Frailty is a geriatric syndrome that leaves people vulnerable to adverse outcomes. In cardiac surgery, minimal data describe associations between frailty and patient-centred outcomes. Our objective was to estimate the association between frailty and days alive at home after cardiac surgery.
Induced normothermia ameliorates the procoagulant host response in human endotoxaemia
Matthew B.A. Harmon, Nanon F.L. Heijnen, Sanne de Bruin, Niek H. Sperna Weiland, ... Nicole P. Juffermans
doi : 10.1016/j.bja.2021.02.033
Volume 126, Issue 6, June 2021, Pages 1111-1118
Dysregulation of coagulation occurs commonly in sepsis, ranging from mild coagulopathy with decreased platelets to disseminated intravascular coagulation (DIC). We investigated the effect of induced normothermia on coagulation during lipopolysaccharide (LPS)-induced endotoxaemia in healthy volunteers.
Methodology of measuring postoperative cognitive dysfunction: a systematic review
Friedrich Borchers, Claudia D. Spies, Insa Feinkohl, Wolf-Rüdiger Brockhaus, ... Thomas H. Ottens
doi : 10.1016/j.bja.2021.01.035
Volume 126, Issue 6, June 2021, Pages 1119-1127
Postoperative cognitive dysfunction (POCD) is an adverse outcome that impacts patients' quality of life. Its diagnosis relies on formal cognitive testing performed before and after surgery. The substantial heterogeneity in methodology limits comparability and meta-analysis of studies. This systematic review critically appraises the methodology of studies on POCD published since the 1995 Consensus Statement and aims to provide guidance to future authors by providing recommendations that may improve comparability between future studies.
Effects of general anaesthesia during pregnancy on neurocognitive development of the fetus: a systematic review and meta-analysis
Tom Bleeser, Lennart Van Der Veeken, Steffen Fieuws, Sarah Devroe, ... Steffen Rex
doi : 10.1016/j.bja.2021.02.026
Volume 126, Issue 6, June 2021, Pages 1128-1140
The US Food and Drug Administration warned that exposure of pregnant women to general anaesthetics may impair fetal brain development. This review systematically evaluates the evidence underlying this warning.
Behavioural impairments after exposure of neonatal mice to propofol are accompanied by reductions in neuronal activity in cortical circuitry
Hang Zhou, Zhongcong Xie, Ansgar M. Brambrink, Guang Yang
doi : 10.1016/j.bja.2021.01.017
Volume 126, Issue 6, June 2021, Pages 1141-1156
Both animal and retrospective human studies have linked extended and repeated general anaesthesia during early development with cognitive and behavioural deficits later in life. However, the neuronal circuit mechanisms underlying this anaesthesia-induced behavioural impairment are poorly understood.
Morbidity and mortality after anaesthesia in early life: results of the European prospective multicentre observational study, neonate and children audit of anaesthesia practice in Europe (NECTARINE)
Nicola Disma, Francis Veyckemans, Katalin Virag, Tom G. Hansen, ... Robin Sunderland
doi : 10.1016/j.bja.2021.02.016
Volume 126, Issue 6, June 2021, Pages 1157-1172
Neonates and infants requiring anaesthesia are at risk of physiological instability and complications, but triggers for peri-anaesthetic interventions and associations with subsequent outcome are unknown.
Difficult tracheal intubation in neonates and infants. NEonate and Children audiT of Anaesthesia pRactice IN Europe (NECTARINE): a prospective European multicentre observational study
Nicola Disma, Katalin Virag, Thomas Riva, Jost Kaufmann, ... Vir?g Katalin
doi : 10.1016/j.bja.2021.02.021
Volume 126, Issue 6, June 2021, Pages 1173-1181
Neonates and infants are susceptible to hypoxaemia in the perioperative period. The aim of this study was to analyse interventions related to anaesthesia tracheal intubations in this European cohort and identify their clinical consequences.
‘Desire for more analgesic treatment’: pain and patient-reported outcome after paediatric tonsillectomy and appendectomy
Ulrike M. Stamer, Kyra Bernhart, Thomas Lehmann, Maria Setzer, ... Winfried Meissner
doi : 10.1016/j.bja.2020.12.047
Volume 126, Issue 6, June 2021, Pages 1182-1191
Insufficiently treated pain after paediatric appendectomy and tonsillectomy is frequent. We aimed to identify variables associated with poor patient-reported outcomes.
Persistent opioid use after surgical treatment of paediatric fracture
Haoyan Zhong, Hannah N. Ladenhauf, Lauren A. Wilson, Jiabin Liu, ... Stavros G. Memtsoudis
doi : 10.1016/j.bja.2020.12.044
Volume 126, Issue 6, June 2021, Pages 1192-1199
The opioid epidemic is one of the most pressing public health crises in the USA. With fractures being amongst the most common reasons for a child to require surgical intervention and receive post-surgical pain management, characterisation of opioid prescription patterns and risk factors is critical. We hypothesised that the numbers of paediatric patients receiving opioids, or who developed persistent opioid use, are significant, and a number of risk factors for persistent opioid use could be identified.
Epidural blood patch for post-dural puncture headaches in adult and paediatric patients with malignancies: a review
Kyle J. Morgan, Rahul Mohan, Seth E. Karol, Jamie Flerlage
doi : 10.1016/j.bja.2020.11.041
Volume 126, Issue 6, June 2021, Pages 1200-1207
Surgery and opioids: evidence-based expert consensus guidelines on the perioperative use of opioids in the United Kingdom
Devjit Srivastava, Susan Hill, Suzanne Carty, Mark Rockett, ... Paul Wilkinson
doi : 10.1016/j.bja.2021.02.030
Volume 126, Issue 6, June 2021, Pages 1208-1216
Association between sex and perioperative opioid prescribing for total joint arthroplasty: a retrospective population-based study
Ellen M. Soffin, Lauren A. Wilson, Jiabin Liu, Jashvant Poeran, Stavros G. Memtsoudis
doi : 10.1016/j.bja.2020.12.046
Volume 126, Issue 6, June 2021, Pages 1217-1225
Scarce data exist on differential opioid prescribing between men and women in the pre-, peri-, and postoperative phases of care among patients undergoing total hip/knee arthroplasty (THA/TKA).
Ventilation strategies for front of neck airway rescue: an in silico study
Marianna Laviola, Christian Niklas, Anup Das, Declan G. Bates, Jonathan G. Hardman
doi : 10.1016/j.bja.2021.01.030
Volume 126, Issue 6, June 2021, Pages 1226-1236
During induction of general anaesthesia a ‘cannot intubate, cannot oxygenate’ (CICO) situation can arise, leading to severe hypoxaemia. Evidence is scarce to guide ventilation strategies for small-bore emergency front of neck airways that ensure effective oxygenation without risking lung damage and cardiovascular depression.
Environmental sustainability in anaesthesia and critical care. Response to Br J Anaesth 2021; 126: e195–e197
Jodi D. Sherman, Mads P. Sulbaek Andersen, James Renwick, Forbes McGain
doi : 10.1016/j.bja.2020.12.025
Volume 126, Issue 6, June 2021, Pages e193-e195
Climate impacts of anaesthesia
Mary E. Slingo, Julia M. Slingo
doi : 10.1016/j.bja.2021.03.004
Volume 126, Issue 6, June 2021, Pages e195-e197
Sphenopalatine ganglion block for the treatment of post-dural puncture headache in paediatric patients
Christine N. Svendsen, Mads S. Jespersen, Patricia Duch
doi : 10.1016/j.bja.2021.02.012
Volume 126, Issue 6, June 2021, Pages e197-e198
Sphenopalatine ganglion block: do not give up on it just yet!
M.Anthony Cometa, Yury Zasimovich, Cameron R. Smith
doi : 10.1016/j.bja.2021.02.020
Volume 126, Issue 6, June 2021, Pages e198-e200
Recurrent anaphylaxis to a gelatin-based colloid plasma substitute and to cetuximab following sensitisation to galactose-alpha-1,3-galactose
Julien Serrier, Kathy Khoy, Yann Ollivier, Radj Gervais, ... Delphine Mariotte
doi : 10.1016/j.bja.2021.02.013
Volume 126, Issue 6, June 2021, Pages e200-e202
Surgeons' view of the preoperative intravenous iron to treat anaemia before major abdominal surgery trial. Response to Br J Anaesth 2021; 126: e84–6
Ben Clevenger, Toby Richards, PREVENTT trial
doi : 10.1016/j.bja.2021.02.014
Volume 126, Issue 6, June 2021, Pages e203-e204
Severe rebound pain after peripheral nerve block for ambulatory extremity surgery is an underappreciated problem. Comment on Br J Anaesth 2021; 126: 862–71
Steven Dawson, Scott N. Loewenstein
doi : 10.1016/j.bja.2021.02.017
Volume 126, Issue 6, June 2021, Pages e204-e205
Perioperative sleep in geriatric cardiac surgical patients: a feasibility study using a wireless wearable device
Mohammad Mehdi Kafashan, Orlandrea Hyche, Thomas Nguyen, S.Kendall Smith, ... Ben J.A. Palanca
doi : 10.1016/j.bja.2021.02.018
Volume 126, Issue 6, June 2021, Pages e205-e208
Central venous catheter misplacement into an aberrant pulmonary vein: implications of a congenital variation
Rebecca Smart, Julieta Gegova, Andrew Wade, Andrew Thrower
doi : 10.1016/j.bja.2021.02.029
Volume 126, Issue 6, June 2021, Pages e208-e210
Postoperative quality of recovery measurements as endpoints in comparative anaesthesia studies: a systematic review
Maxime Léger, Maëva Campfort, Cléor Cayla, Sigismond Lasocki, Emmanuel Rineau
doi : 10.1016/j.bja.2021.03.008
Volume 126, Issue 6, June 2021, Pages e210-e212
Microcirculatory effects of landiolol: a double-blind, randomised, controlled study after cardiac surgery
Arnaud Ferraris, Matthias Jacquet-Lagrèze, Laure Cazenave, William Fornier, ... Jean-Luc Fellahi
doi : 10.1016/j.bja.2021.03.013
Volume 126, Issue 6, June 2021, Pages e212-e214
Physiologically variable ventilation and severe asthma. Comment on Br J Anaesth 2020; 125: 1107–16
W. Alan C. Mutch
doi : 10.1016/j.bja.2021.03.016
Volume 126, Issue 6, June 2021, Page e214
Effects of combined oxygen and surgical masks on inspired fraction of oxygen: relevance to COVID-19-induced respiratory failure
Satoshi Hamada, Naoya Tanabe, Toyohiro Hirai
doi : 10.1016/j.bja.2021.02.025
Volume 126, Issue 6, June 2021, Pages e215-e217
Recovery after critical illness in COVID-19 ICU survivors
Alexander J. Parker, Anita Humbir, Pooja Tiwary, Monalisa Mishra, ... Craig Brandwood
doi : 10.1016/j.bja.2021.03.005
Volume 126, Issue 6, June 2021, Pages e217-e219
Rationing oxygen use during total intravenous anaesthesia: a proportionate response?
Morgan Back, George Zhong, Adam Al-Attar, Rebecca Sutton, Cliff Shelton
doi : 10.1016/j.bja.2021.02.031
Volume 126, Issue 6, June 2021, Pages e219-e220
Protection of healthcare workers during aerosol-generating procedures with local exhaust ventilation
Jante S. Sinnige, Fabian O. Kooij, Hans van Schuppen, Markus W. Hollmann, Nicolaas H. Sperna Weiland
doi : 10.1016/j.bja.2021.02.032
Volume 126, Issue 6, June 2021, Pages e219-e220
Effect of personal protective equipment on perioperative anxiety in children and young people
Charlotte Berwick, Edward Benison, James Masters, David Robinson, ... Ijeoma Okonkwo
doi : 10.1016/j.bja.2021.03.006
Volume 126, Issue 6, June 2021, Pages e223-e224
Perioperative risk evaluation in patients scheduled for elective surgery in close relation to their SARS-CoV-2 vaccination
Ulrich Limper, Jerome Defosse, Oliver Schildgen, Frank Wappler
doi : 10.1016/j.bja.2021.03.007
Volume 126, Issue 6, June 2021, Pages e225-e226
Core Topics in Airway Management, 3rd edition, Tim Cook, Michael Seltz Kristensen (Eds.) (2021), Cambridge University Press. $89.99, pp. 330, ISBN No: 9781108419536
Benjamin H. Cloyd, Dane R. Grenda
doi : 10.1016/j.bja.2021.02.010
Volume 126, Issue 6, June 2021, Pages 1237-1238
