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سفارش

The heterogeneity of Alzheimer’s disease 

Masud Husain

doi : 10.1093/brain/awae182

Volume 147, Issue 7, July 2024

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Investigation of network reorganization after epilepsy surgery is worth the effort 

Lucas E Sainburg, Victoria L Morgan

doi : 10.1093/brain/awae172

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Tiam1 is part of a novel mechanism for morphine tolerance and hyperalgesia 

Elizaveta Mangutov, Amynah A Pradhan

doi : 10.1093/brain/awae170

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The readiness potential and the soul: what happens when you resect their seat in the brain? 

Rickard L Sjöberg

doi : 10.1093/brain/awae180

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Academic neurology in the UK: a plea to turn away from the precipice 

Helen Devine, Edwin Jabbari, James Scott, Arpan R Mehta, Ruth Dobson, Simon Mead

doi : 10.1093/brain/awae151

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Limitation of life sustaining therapy in disorders of consciousness: ethics and practice

India A Lissak, Michael J Young

doi : 10.1093/brain/awae060

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Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis 

Emma L Clayton, Laura Huggon, Michael A Cousin, Sarah Mizielinska

doi : 10.1093/brain/awae074

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Cholinergic changes in Lewy body disease: implications for presentation, progression and subtypes

Niels Okkels, Michel J Grothe, John-Paul Taylor, Steen Gregers Hasselbalch, Tatyana D Fedorova, Karoline Knudsen, Sygrid van der Zee, Teus van Laar, Nicolaas I Bohnen, Per Borghammer, Jacob Horsager

doi : 10.1093/brain/awae069

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APP antisense oligonucleotides reduce amyloid-β aggregation and rescue endolysosomal dysfunction in Alzheimer’s disease 

doi : 10.1093/brain/awae092

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RTN2 deficiency results in an autosomal recessive distal motor neuropathy with lower limb spasticity 

Reza Maroofian, Payam Sarraf, Thomas J O’Brien, Mona Kamel, Arman Cakar, Nour Elkhateeb, Tracy Lau, Siddaramappa Jagdish Patil, Christopher J Record, Alejandro Horga, Miriam Essid, Laila Selim, Hanene Benrhouma, Thouraya Ben Younes, Giovanni Zifarelli, Alistair T Pagnamenta, Genomics England Research Consortium Peter Bauer, Mukhran Khundadze, Andrea Mirecki, Sara Mahmoud Kamel, Mohamed A Elmonem, Ehsan Ghayoor Karimiani, Yalda Jamshidi, Amaka C Offiah, Alexander M Rossor, Ilhem Ben Youssef-Turki, Christian A Hübner, Pinki Munot, Mary M Reilly, André E X Brown, Sara Nagy, Henry Houlden

doi : 10.1093/brain/awae091

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Distinct neuronal circuits mediate cortical hyperexcitability in amyotrophic lateral sclerosis

Nathan Pavey, Andrew Hannaford, Mehdi van den Bos, Matthew C Kiernan, Parvathi Menon, Steve Vucic

doi : 10.1093/brain/awae049

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Clinicopathological correlates in the frontotemporal lobar degeneration–motor neuron disease spectrum 

�lvaro Carbayo, Sergi Borrego-Écija, Janina Turon-Sans, Elena Cortés-Vicente, Laura Molina-Porcel, Jordi Gascón-Bayarri, Miguel �ngel Rubio, Mónica Povedano, Josep Gámez, Javier Sotoca, Raúl Juntas-Morales, Miriam Almendrote, Marta Marquié, Raquel Sánchez-Valle, Ignacio Illán-Gala, Oriol Dols-Icardo, Sara Rubio-Guerra, Sara Bernal, Marta Caballero-�vila, Ana Vesperinas, Ellen Gelpi, Ricard Rojas-García

doi : 10.1093/brain/awae011

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TREM2 variants that cause early dementia and increase Alzheimer’s disease risk affect gene splicing

Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna N Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska

doi : 10.1093/brain/awae014

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A cell autonomous regulator of neuronal excitability modulates tau in Alzheimer’s disease vulnerable neurons 

Patricia Rodriguez-Rodriguez, Luis Enrique Arroyo-Garcia, Christina Tsagkogianni, Lechuan Li, Wei Wang, �kos Végvári, Isabella Salas-Allende, Zakary Plautz, Angel Cedazo-Minguez, Subhash C Sinha, Olga Troyanskaya, Marc Flajolet, Vicky Yao, Jean-Pierre Roussarie

doi : 10.1093/brain/awae051

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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings 

Hannah Baumeister, Jacob W Vogel, Philip S Insel, Luca Kleineidam, Steffen Wolfsgruber, Melina Stark, Helena M Gellersen, Renat Yakupov, Matthias C Schmid, Falk Lüsebrink, Frederic Brosseron, Gabriel Ziegler, Silka D Freiesleben, Lukas Preis, Luisa-Sophie Schneider, Eike J Spruth, Slawek Altenstein, Andrea Lohse, Klaus Fliessbach, Ina R Vogt, Claudia Bartels, Björn H Schott, Ayda Rostamzadeh, Wenzel Glanz, Enise I Incesoy, Michaela Butryn, Daniel Janowitz, Boris-Stephan Rauchmann, Ingo Kilimann, Doreen Goerss, Matthias H Munk, Stefan Hetzer, Peter Dechent, Michael Ewers, Klaus Scheffler, Anika Wuestefeld, Olof Strandberg, Danielle van Westen, Niklas Mattsson-Carlgren, Shorena Janelidze, Erik Stomrud, Sebastian Palmqvist, Annika Spottke, Christoph Laske, Stefan Teipel, Robert Perneczky, Katharina Buerger, Anja Schneider, Josef Priller, Oliver Peters, Alfredo Ramirez, Jens Wiltfang, Michael T Heneka, Michael Wagner, Emrah Düzel, Frank Jessen, Oskar Hansson, David Berron

doi : 10.1093/brain/awae118

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Cerebrospinal fluid biomarker panel for synaptic dysfunction in a broad spectrum of neurodegenerative diseases 

Johanna Nilsson, Alexa Pichet Binette, Sebastian Palmqvist, Wagner S Brum, Shorena Janelidze, Nicholas J Ashton, Nicola Spotorno, Erik Stomrud, Johan Gobom, Henrik Zetterberg, Ann Brinkmalm, Kaj Blennow, Oskar Hansson

doi : 10.1093/brain/awae032

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Subcortical tau is linked to hypoperfusion in connected cortical regions in 4-repeat tauopathies

Sebastian N Roemer, Matthias Brendel, Johannes Gnörich, Maura Malpetti, Mirlind Zaganjori, Andrea Quattrone, Mattes Gross, Anna Steward, Anna Dewenter, Fabian Wagner, Amir Dehsarvi, Christian Ferschmann, Stephan Wall, Carla Palleis, Boris S Rauchmann, Sabrina Katzdobler, Alexander Jäck, Anna Stockbauer, Urban M Fietzek, Alexander M Bernhardt, Endy Weidinger, Andreas Zwergal, Sophia Stöcklein, Robert Perneczky, Henryk Barthel, Osama Sabri, Johannes Levin, Günter U Höglinger, Nicolai Franzmeier

doi : 10.1093/brain/awae174

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Phenoconversion in pure autonomic failure: a multicentre prospective longitudinal cohort study

Patricio Millar Vernetti, Lucy Norcliffe-Kaufmann, Jose-Alberto Palma, Italo Biaggioni, Cyndya A Shibao, Amanda Peltier, Roy Freeman, Christopher Gibbons, David S Goldstein, Phillip A Low, Wolfgang Singer, Elizabeth A Coon, Mitchell G Miglis, Gregor K Wenning, Alessandra Fanciulli, Steven Vernino, Rebecca A Betensky, Horacio Kaufmann

doi : 10.1093/brain/awae033

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The effect of Huntington’s disease on cognitive and physical motivation 

Kelly J Atkins, Sophie C Andrews, Julie C Stout, Trevor T J Chong

doi : 10.1093/brain/awae023

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Adaptive coding of reward in schizophrenia, its change over time and relationship to apathy 

Mariia Kaliuzhna, Fabien Carruzzo, Noémie Kuenzi, Philippe N Tobler, Matthias Kirschner, Tal Geffen, Teresa Katthagen, Kerem Böge, Marco M Zierhut, Florian Schlagenhauf, Stefan Kaiser

doi : 10.1093/brain/awae112

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ZSCAN10 deficiency causes a neurodevelopmental disorder with characteristic oto-facial malformations 

Lucia Laugwitz, Fubo Cheng, Stephan C Collins, Alexander Hustinx, Nicolas Navarro, Simon Welsch, Helen Cox, Tzung-Chien Hsieh, Aswinkumar Vijayananth, Rebecca Buchert, Benjamin Bender, Stephanie Efthymiou, David Murphy, Faisal Zafar, Nuzhat Rana, Ute Grasshoff, Ruth J Falb, Mona Grimmel, Annette Seibt, Wenxu Zheng, Hamid Ghaedi, Marie Thirion, Sébastien Couette, Reza Azizimalamiri, Saeid Sadeghian, Hamid Galehdari, Mina Zamani, Jawaher Zeighami, Alireza Sedaghat, Samira Molaei Ramshe, Ali Zare, Behnam Alipoor, Dirk Klee, Marc Sturm, Genomics England Research Consortium Stephan Ossowski, Henry Houlden, Olaf Riess, Dagmar Wieczorek, Ryan Gavin, Reza Maroofian, Peter Krawitz, Binnaz Yalcin, Felix Distelmaier, Tobias B Haack

doi : 10.1093/brain/awae058

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Connectome reorganization associated with temporal lobe pathology and its surgical resection 

Sara Larivière, Bo-yong Park, Jessica Royer, Jordan DeKraker, Alexander Ngo, Ella Sahlas, Judy Chen, Raúl Rodríguez-Cruces, Yifei Weng, Birgit Frauscher, Ruoting Liu, Zhengge Wang, Golia Shafiei, Bratislav Mišić, Andrea Bernasconi, Neda Bernasconi, Michael D Fox, Zhiqiang Zhang, Boris C Bernhardt

doi : 10.1093/brain/awae141

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Spike ripples localize the epileptogenic zone best: an international intracranial study

Wen Shi, Dana Shaw, Katherine G Walsh, Xue Han, Uri T Eden, Robert M Richardson, Stephen V Gliske, Julia Jacobs, Benjamin H Brinkmann, Gregory A Worrell, William C Stacey, Birgit Frauscher, John Thomas, Mark A Kramer, Catherine J Chu

doi : 10.1093/brain/awae037

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Tiam1-mediated maladaptive plasticity underlying morphine tolerance and hyperalgesia

Changqun Yao, Xing Fang, Qin Ru, Wei Li, Jun Li, Zeinab Mehsein, Kimberley F Tolias, Lingyong Li

doi : 10.1093/brain/awae106

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Dissociation of reading and naming in ventral occipitotemporal cortex

Oscar Woolnough, Nitin Tandon

doi : 10.1093/brain/awae027

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Subtitled speech: the neural mechanisms of ticker-tape synaesthesia 

Fabien Hauw, Benoît Béranger, Laurent Cohen

doi : 10.1093/brain/awae114

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Increased frequency and mortality in persons with neurological disorders during COVID-19

Candace M Marsters, Jeffrey A Bakal, Grace Y Lam, Finlay A McAlister, Christopher Power

doi : 10.1093/brain/awae117

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HSV-1 reactivation results in post-herpetic neuralgia by upregulating Prmt6 and inhibiting cGAS-STING

Erliang Kong, Tong Hua, Jian Li, Yongchang Li, Mei Yang, Ruifeng Ding, Haowei Wang, Huawei Wei, Xudong Feng, Chaofeng Han, Hongbin Yuan

doi : 10.1093/brain/awae053

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Characterization of cortico-meningeal translocator protein expression in multiple sclerosis

Elena Herranz, Constantina A Treaba, Valeria T Barletta, Ambica Mehndiratta, Russell Ouellette, Jacob A Sloane, Carolina Ionete, Suma Babu, Marina Mastantuono, Stefano Magon, Marco L Loggia, Meena M Makary, Jacob M Hooker, Ciprian Catana, Revere P Kinkel, Richard Nicholas, Eric C Klawiter, Roberta Magliozzi, Caterina Mainero

doi : 10.1093/brain/awae030

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HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease

Selina M Yogeshwar, Sergio Muñiz-Castrillo, Lidia Sabater, Vicente Peris-Sempere, Vamsee Mallajosyula, Guo Luo, Han Yan, Eric Yu, Jing Zhang, Ling Lin, Flavia Fagundes Bueno, Xuhuai Ji, Géraldine Picard, Véronique Rogemond, Anne Laurie Pinto, Anna Heidbreder, Romana Höftberger, Francesc Graus, Josep Dalmau, Joan Santamaria, Alex Iranzo, Bettina Schreiner, Maria Pia Giannoccaro, Rocco Liguori, Takayoshi Shimohata, Akio Kimura, Yoya Ono, Sophie Binks, Sara Mariotto, Alessandro Dinoto, Michael Bonello, Christian J Hartmann, Nicola Tambasco, Pasquale Nigro, Harald Prüss, Andrew McKeon, Mark M Davis, Sarosh R Irani, Jérôme Honnorat, Carles Gaig, Carsten Finke, Emmanuel Mignot

doi : 10.1093/brain/awae048

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Biallelic truncating variants in PACSIN3 cause childhood-onset myopathy with hyperCKaemia

Felix Distelmaier, Abdullah Sezer, Christina Helm, Stephan Waldmüller, Annette Seibt, Andrea Gangfuß, Heike Kölbel, Ulrike Schara-Schmidt, Deniz Yuksel, Beril Talim, Ertan Mayatepek, Stefan Nikolin, Joachim Weis, Andreas Roos, Tobias B Haack

doi : 10.1093/brain/awae099

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Correction to: Multimodal mapping of regional brain vulnerability to focal cortical dysplasia 

doi : 10.1093/brain/awae076

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Correction to: Disrupted daily activity/rest cycles in relation to daily cortisol rhythms of home-dwelling patients with early Alzheimer's dementia 

doi : 10.1093/brain/awae103

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