Version May 2024
| Drug | Dose | Duration |
| Preferred topical therapies* | ||
| Ketoconazole 2% shampoo | One 5-minute application daily | 3 consecutive days (a single application may be similarly effective) |
| Various other azole antifungal preparations (including creams, solutions, lotions, foams, and gels)¶ | Once- or twice-daily application | Typically 2 weeks (range in clinical studies of 1 to 4 weeks) |
| Terbinafine 1% cream | Twice-daily application | 1 week |
| Selenium sulfide 2.25% shampoo or 2.5% lotion | One 10-minute application daily | 1 week |
| Other topical therapies | ||
| Zinc pyrithione 1% shampoo | One 5-minute application daily | 2 weeks |
| Ciclopirox 0.77% cream | Twice-daily application | 2 weeks |
| Preferred oral therapiesΔ | ||
| Fluconazole | 300 mg orally once weekly for adults | 2 weeks |
| Itraconazole | 200 mg orally once daily for adults | 5 days |
* We frequently treat with ketoconazole 2% shampoo because of ease of application and the short course of treatment.
¶ Topical azole antifungals include clotrimazole 1%, econazole 1%, efinaconazole 10%, ketoconazole 2%, luliconazole 1%, miconazole 2%, oxiconazole 1%, sertaconazole 2%, and sulconazole 1%. For additional detail on available formulations and frequency of application refer to the Lexicomp drug-specific monographs included with UpToDate.
Δ Oral therapy is reserved for patients with disease refractory to topical therapy or widespread disease that makes the application of topical therapy difficult. Oral terbinafine and griseofulvin are not effective; oral ketoconazole is not recommended (refer to topic discussion). Doses provided are for adults.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
