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Examples of inflammatory versus noninflammatory arthritis

Examples of inflammatory versus noninflammatory arthritis
Noninflammatory*: <2000 WBC per mm3 (2 × 109 per L) Inflammatory: >2000 WBC per mm3
Osteoarthritis Septic arthritis
Trauma Crystal-induced monoarthritis (eg, gout, pseudogout)
Avascular necrosis Rheumatoid arthritis and juvenile idiopathic arthritis
Charcot arthropathy Spondyloarthritis
Hemochromatosis Systemic lupus erythematosus
Tenosynovial giant cell tumor Lyme disease

WBC: white blood cell.

* Overtly hemorrhagic noninflammatory fluid may have a WBC count approaching that of blood.

¶ Synovial fluid analysis in patients with septic arthritis often shows more than 90% polymorphonuclear neutrophilic leukocytes.
Adapted with permission from Chokkalingam Siva, M.D., Celso Velazquez, M.D., and Richard Brasington, M.D. Diagnosing Acute Monoarthritis in Adults: A Practical Approach for the Family Physician, American Family Physician, 2003;68(1):83-90. © 2003. All Rights Reserved.
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