Examples of inflammatory versus noninflammatory arthritis

Noninflammatory*: <2000 WBC per mm³ (2 x 10⁹ per L)	Inflammatory: >2000 WBC per mm³
Osteoarthritis	Septic arthritis^¶
Trauma	Crystal-induced monoarthritis (eg, gout, pseudogout)
Avascular necrosis	Rheumatoid arthritis and juvenile idiopathic arthritis
Charcot's arthropathy	Spondyloarthritis
Hemochromatosis	Systemic lupus erythematosus
Pigmented villonodular synovitis	Lyme disease

WBC: white blood cell.
* Overtly hemorrhagic noninflammatory fluid may have a WBC count approaching that of blood.
¶ Synovial fluid analysis in patients with septic arthritis often shows more than 90% polymorphonuclear neutrophilic leukocytes.

Reprinted with permission from Diagnosing Acute Monoarthritis in Adults: A Practical Approach for the Family Physician, July 1, 2003, Vol 68, No 1, American Family Physician. Copyright © 2003 American Academy of Family Physicians. All Rights Reserved.

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Examples of inflammatory versus noninflammatory arthritis