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De Perrot classification of malignant potential of pleural solitary fibrous tumors

De Perrot classification of malignant potential of pleural solitary fibrous tumors
Stage Definition Risk of recurrence, %
0 Pedunculated tumor without histologic signs of malignancy* 2
I Sessile or "inverted" tumor without histologic signs of malignancy* 8
II Pedunculated tumor with histologic signs of malignancy* 14
III Sessile or "inverted" tumor with histologic signs of malignancy* 63
IV Multiple synchronous metastatic tumors  
* Malignant behavior is suggested by the presence of the following histologic features: high cellularity with crowding and overlapping of nuclei, cellular pleomorphism, high mitotic count (more than 4 per 10 high-power fields), necrosis, or stromal/vascular invasion.
Original figure modified for this publication. de Perrot M, Fischer S, Bründler MA, et al. Solitary Fibrous Tumors of the Pleura. Ann Thorac Surg 2002; 74:285. Table used with the permission of Elsevier Inc. All rights reserved.
Graphic 101069 Version 3.0

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