L-Lysine: Drug information

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)

Brand Names: US

Lysine4000 [OTC] [DSC]

Pharmacologic Category

Nutritional Supplement

Dosing: Adult

Dietary supplement

Dietary supplement: Oral: Note: Dosage varies; also consult specific product information.

Capsule: One capsule 1 to 3 times daily.

Powder: ¹/₄ level teaspoonful once daily.

Tablet: 1 tablet twice daily.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Older Adult

Refer to adult dosing.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Packet, Oral:

Lysine4000: 4000 mg (30 ea [DSC])

Tablet, Oral:

Generic: 500 mg, 1000 mg

Generic Equivalent Available: US

Yes

Pricing: US

Tablets (Lysine HCl Oral)

1000 mg (per each): $0.12

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Adult

Oral: Formulation-specific administration instructions may vary; refer to manufacturer’s labeling.

Use: Labeled Indications

Dietary supplement: Essential amino acid that regulates immune response helping to manage stress in body.

Pregnancy Considerations

L-lysine crosses the placenta in humans (Ronzoni, 1999; Schneider, 1979). Lysine is an essential amino acid. The RDA for lysine is increased in pregnant women (IOM, 2005).

Breastfeeding Considerations

Lysine is an essential amino acid and is found in breast milk. The RDA for lysine is increased in breast-feeding women (IOM, 2005).

Brand Names: International

International Brand Names by Country

For country code abbreviations (show table)

(AE) United Arab Emirates: L lysine;
(AU) Australia: Bioglan lysine | Blooms lysine | L lysine | L Lysine | Lysine | Nature's own cold sore relief lysine | Nature's Own Double Strength Cold Sore Relief | Natures way cold sore defence | Pan l - lysine | Pretorius Professional Lysine Cold Sore;
(BR) Brazil: Resist;
(DE) Germany: Alpha-l-lysin herpes-/virenschutz | Arktis touch l-lysin | L lysin | L lysine | Lysin | Ntm Lysine | Pure encapsulations L lysin | Sana lysin | Touch l lysin | Vimergy L Lysine;
(EE) Estonia: L-lusiin;
(JO) Jordan: L lysine;
(LB) Lebanon: L lysine | Lysinel;
(LV) Latvia: Lizins;
(MX) Mexico: L-lisina solgar;
(MY) Malaysia: L lysin;
(NO) Norway: L lysine;
(NZ) New Zealand: Nature's own cold sore relief lysine | Natures own L Lysine | Nutra-life lysine;
(TH) Thailand: Vistra l lysine monohydrochloride | Vitamate l lysine;
(TR) Turkey: Solgar L Lysine;
(ZA) South Africa: Essentials l lysine | Gold l lysine | Happy me l lysine | L lysine | L Lysine

IOM (Institute of Medicine), Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids (Macronutrients), Washington, DC: The National Academies Press, 2005.
L-Lysine [prescribing information]. Livonia, MI: Major Pharmaceuticals; December 2018.
Ronzoni S, Marconi AM, Cetin I, et al, "Umbilical Amino Acid Uptake at Increasing Maternal Amino Acid Concentrations: Effect of a Maternal Amino Acid Infusate," Am J Obstet Gynecol, 1999, 181(2):477-83. [PubMed 10454703]
Schneider H, Möhlen KH, and Dancis J, "Transfer of Amino Acids Across the in vitro Perfused Human Placenta," Pediatr Res, 1979, 13(4 Pt 1):236-40. [PubMed 471582]

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L-Lysine: Drug information