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Summary of immune response (seroconversion), vaccine effectiveness, and duration of immunity for the measles, rubella, and mumps component of the measles, mumps, rubella combination vaccine*

Summary of immune response (seroconversion), vaccine effectiveness, and duration of immunity for the measles, rubella, and mumps component of the measles, mumps, rubella combination vaccine*
Disease Seroconversion after 1 dose
Median % (range)
Vaccine effectiveness
Median % (range)
Duration of immunity
1 dose 2 doses 1 dose 2 doses
Measles 96 (84 to 100) 93 (39 to 100) 97 (67 to 100) ≥11 years ≥15 years
Rubella 99 (95 to 100) 97 (94 to 100) NA ≥16 years ≥15 years
Mumps 94 (89 to 97) 78 (49 to 92) 88 (66 to 95) ≥10 years ≥15 years
NA: not applicable.
* Data were obtained from multiple studies describing immune response (seroconversion), vaccine effectiveness, and duration of immunity for the measles, rubella, and mumps component of the measles, mumps, rubella, combination vaccine.
Reproduced from: McLean HQ, Fiebelkorn AP, Temte JL, et al. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: Summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2013; 62:1.
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