Version May 2024
| Characteristics | Ulcerative proctitis | Chronic radiation proctopathy | Diversion proctitis |
| Shared clinical features | Rectal bleeding, diarrhea, urgency, tenesmus, incontinence, pelvic pain, sense of incomplete evacuation | ||
| Disease-specific clinical features | Risk of proximal extension of inflammation; ulcerative proctitis improves after fecal diversion | Excessive bleeding; inflammation persists even after fecal diversion | Bloody mucus discharge; inflammation resolves after reestablishment of continuity |
| Shared endoscopic features | Edema, erythema, friability, ulcer, exudates | ||
| Disease-specific endoscopic features | Sharp demarcation of diseased and non-diseased segments of distal large bowel; inflammatory polyps | Angiectasia or arteriovenous malformation-like lesions | Anal or distal rectal stricture, bleeding induced by endoscopic air insufflation; "cat scratch" |
| Shared histologic features | No definite shared histologic features | ||
| Disease-specific histologic features | Prominent basal lymphoplasmacytosis | Dilated, tortuous capillaries, prominent endothelial cell nuclei, surrounded by a cuff of hyalinized lamina propria | Follicular lymphoid hyperplasia |
| Other histologic features | Epithelial injury from mucin depletion, cryptitis, crypt abscess, erosion and ulceration; crypt distortion; Paneth cell metaplasia; hypertrophy of muscularis mucosae in some cases | Variable degree of epithelial injury, crypt distortion, erosion and ulceration; sclerosis of submucosal arteries, the presence of atypical stellate fibroblasts, and secondary chronic ischemic changes such as crypt atrophy and Paneth cell metaplasia | Diffuse mild acute inflammation, lymphoplasmacytic infiltrate most dense in the superficial epithelia; may show mucin depletion, cryptitis, crypt abscess, crypt atrophy, and Paneth cell metaplasia |
آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
