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Bismuth subgallate: Drug information

Bismuth subgallate: Drug information
(For additional information see "Bismuth subgallate: Patient drug information" and see "Bismuth subgallate: Pediatric drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Brand Names: US
  • Devrom [OTC]
Pharmacologic Category
  • Gastrointestinal Agent, Miscellaneous
Dosing: Adult
Flatulence and feces deodorizer

Flatulence and feces deodorizer: Oral: 1 to 2 capsules or chewable tablets up to 4 times daily (maximum: 8 capsules or chewable tablets per 24 hours).

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Pediatric

(For additional information see "Bismuth subgallate: Pediatric drug information")

Flatulence and feces deodorizer

Flatulence and feces deodorizer: Children ≥12 years and Adolescents: Oral: 1 to 2 capsules or chewable tablets up to 4 times daily; maximum daily dose: 8 capsules or chewable tablets/24 hours.

Dosing: Kidney Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Dosing: Hepatic Impairment: Pediatric

There are no dosage adjustments provided in the manufacturer’s labeling.

Adverse Reactions

The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.

Frequency not defined.

Gastrointestinal: Darkening of stools, melanoglossia

Warnings/Precautions

Other warnings/precautions:

• Self-medication (OTC use): A temporary harmless darkening of the stool and/or tongue may occur with use. Bismuth subgallate does not reduce the odor due to faulty personal hygiene.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Capsule, Oral:

Devrom: 200 mg

Tablet Chewable, Oral:

Devrom: 200 mg [DSC]

Generic Equivalent Available: US

No

Pricing: US

Capsules (Devrom Oral)

200 mg (per each): $0.17

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Administration: Adult

Oral: Chewable tablets should be chewed thoroughly.

Administration: Pediatric

Oral: Chewable tablets should be chewed thoroughly.

Use: Labeled Indications

Flatulence and feces deodorizer: Eliminating or reducing odor from flatulence and feces

Metabolism/Transport Effects

None known.

Drug Interactions

Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program by clicking on the “Launch drug interactions program” link above.

Bismuth Subcitrate: Bismuth-Containing Compounds may enhance the neurotoxic effect of Bismuth Subcitrate. Risk X: Avoid combination

Mechanism of Action

Adsorbs extra water in large intestine, as well as toxins; forms a protective coat on the intestinal mucosa.

Pharmacokinetics (Adult Data Unless Noted)

Absorption: Bismuth is minimally absorbed across the GI tract (Lione 1988)

  1. Devrom (bismuth subgallate) capsules [prescribing information]. Salt Lake City, UT: Parthenon; December 2018.
  2. Devrom (bismuth subgallate) chewable tablets [prescribing information]. Salt Lake City, UT: Parthenon; December 2018.
  3. Lione A. Polychlorinated biphenyls and reproduction. Reprod Toxicol. 1988;2(2):83-89. [PubMed 2980410]
Topic 101846 Version 50.0

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