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Vitamin B5 (pantothenic acid): Drug information

Vitamin B5 (pantothenic acid): Drug information
(For additional information see "Vitamin B5 (pantothenic acid): Patient drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Pharmacologic Category
  • Vitamin, Water Soluble
Dosing: Adult
Pantothenic acid deficiency

Pantothenic acid deficiency: OTC labeling: Oral: One tablet daily.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling.

Dosing: Older Adult

Refer to adult dosing.

Adverse Reactions

There are no adverse reactions listed in the manufacturer's labeling.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Tablet, Oral:

Generic: 100 mg, 200 mg, 500 mg

Tablet, Oral [preservative free]:

Generic: 500 mg [DSC]

Generic Equivalent Available: US

Yes

Pricing: US

Tablets (Pantothenic Acid Oral)

500 mg (per each): $0.12

Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.

Use: Labeled Indications

Pantothenic acid deficiency: Dietary supplement to treat pantothenic acid deficiency.

Metabolism/Transport Effects

None known.

Drug Interactions

There are no known significant interactions.

Pregnancy Considerations

Water soluble vitamins cross the placenta (IOM, 1998).

Breastfeeding Considerations

Pantothenic acid is found in breast milk; concentrations may be increased by use of maternal supplements (IOM, 1998)

Dietary Considerations

Dietary adequate intake (AI) (IOM 1998):

1 to 6 months: 1.7 mg/day

7 to 12 months: 1.8 mg/day

1 to 3 years: 2 mg/day

4 to 8 years: 3 mg/day

9 to 13 years: 4 mg/day

≥14 years: 5 mg/day

Pregnancy: 6 mg/day

Lactation: 7 mg/day

Mechanism of Action

Pantothenic acid is required for the synthesis and maintenance of coenzyme A.

Pharmacokinetics (Adult Data Unless Noted)

Absorption: Absorbed in the intestine

Metabolism: Hydrolyzed in the intestine to coenzyme A

Excretion: Urine

Brand Names: International
International Brand Names by Country
For country code abbreviations (show table)

  • (AU) Australia: Thompson's B5 | Vit b5 | Vitamin b5;
  • (BD) Bangladesh: Calcinate | Calcipan | Pantoson;
  • (BR) Brazil: Acido pantotenico;
  • (CN) China: Cal.pantothenate;
  • (DE) Germany: Arktis vita b5 | Naturafit pantothensaeure | Pantotheenzuur 250 | Pantothensaeure | Pure encapsulations pantothensaeure | Vitamin b5;
  • (IN) India: Kerablak | Sigma-pantothenate;
  • (LB) Lebanon: Pantothenic acid;
  • (NZ) New Zealand: Solgar pantothenic acid | Vitamin b5;
  • (PK) Pakistan: Calcipan t | Caldipan | V-pan;
  • (PY) Paraguay: Pantothenic acid;
  • (TH) Thailand: Pantothenic | Pantothenic acid | Vitamin b5;
  • (ZA) South Africa: Vitaforce vitamin b5
  1. IOM (Institute of Medicine), Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin and Choline, Washington, DC: National Academy Press, 1998.
  2. Pantothenic acid [product labeling]. Livonia, MI: Rugby Laboratories; October 2016.
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