Diseases associated with familial pleuropulmonary blastoma

Lungs	Pleuropulmonary blastoma (PPB)
Lungs	Lung cysts
Urinary tract	Cystic nephroma
	Renal cysts
	Wilms tumor
	Bladder cancer (rhabdomyosarcoma, transition-cell carcinoma, papilloma)
Intestine	Polyps
Thyroid	Nodular hyperplasias
Thyroid	Follicular and papillary carcinomas
Blood	Leukemia/lymphoma
Gonadal tumors	Stromal sex cord tumors (Sertoli Leydig)
Gonadal tumors	Germ cell tumors (seminoma, dysgerminoma)
Brain tumors	Medulloblastoma
	Glioblastoma multiforme
	Ependymoma
	Sarcoma
Other	Nasal chondromesenchymal hamartoma
	Hepatic cystic mesenchymal hamartoma
	Synovial sarcoma
	Globe melanosarcoma or medulloepithelioma
	Neuroblastoma
	Anaplastic carcinoma of the pharynx
	Neurofibromatosis type 1

These diseases were associated with pleuropulmonary blastoma (PPB) in the index case or family members, as reported from the International Pleuropulmonary Blastoma Registry.

Data from: Priest JR, Williams GM, Hill DA, et al. Pulmonary cysts in early childhood and the risk of malignancy. Pediatr Pulmonol 2009; 44:14.

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Diseases associated with familial pleuropulmonary blastoma