Estimated risk¶ | |
Prematurity | |
GA <28 weeks | OR 60.9, 95% CI 34.3-108.0 |
GA 28 to 31 weeks | OR 32.0, 95% CI 20.6-49.5 |
GA 32 to 36 weeks | OR 5.0, 95% CI 2.9-8.6 |
Low birth weight | |
<1500 g | OR 44.5, 95% CI 35.6-55.5 |
1500 to 2499 g | OR 7.6, 95% CI 6.0-9.7 |
Intrauterine infection | |
Any maternal infection during pregnancy | RR 2.5, 95% CI 1.9-3.2 |
Maternal chorioamnionitis | RR 2.9, 95% CI 2.0-4.2 |
Preeclampsia | OR 1.9, 95% CI 1.5-2.5 |
Placental abruption | OR 10.9, 95% CI 8.4-14.1 |
Multiple pregnancy | OR 3.7, 95% CI 3.0-4.5 |
Heavy maternal alcohol consumption | OR 3.3, 95% CI 1.3-8.5 |
Maternal smoking | HR 1.8, 95% CI 1.1-2.9 |
Maternal trauma during pregnancy | HR 1.33, 95% CI 1.18-1.50 |
Maternal obesity (prepregnancy BMI ≥30) | RR 1.6, 95% CI 1.1-2.2 |
Small size for gestational age | OR 3.7, 95% CI 3.1-4.4 |
Other congenital abnormalities | OR 5.2, 95% CI 2.8-9.7 |
Apgar <7 at 5 minutes | OR 27.0, 95% CI 23.5-31.2 |
Neonatal infection | OR 14.7, 95% CI 1.7-126.5 |
Respiratory distress syndrome | HR 2.1, 95% CI 1.4-3.1 |
Requiring mechanical ventilation after birth | OR 2.4, 95% CI 2.4-4.5 |
Requiring antibiotic therapy after birth | OR 1.7, 95% CI 1.3-2.2 |
Neonatal seizures | OR 7.4, 95% CI 4.8-11.6 |
GA: gestational age; OR: odds ratio; RR: relative risk; HR: hazard ratio; BMI: body mass index; CP: cerebral palsy.
* This table summarizes prenatal and perinatal factors that have been reported to be associated with an increased risk of CP. Studies have identified associations with these factors and CP; however, in most cases, a causal relationship has not been established. While the estimated risks associated with individual factors are presented, in many cases, CP is multifactorial and multiple risk factors coexist. In most studies, prematurity and low birth weight are the strongest and most consistent predictors of CP.
¶ Baseline risk of CP is approximately 0.2%.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟