Version May 2024
Muscle/joint pain: Topical: Apply a liberal amount to affected area as needed up to 4 times daily.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Refer to adult dosing.
Children ≥12 years: Refer to adult dosing.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified.
1% to 10%:
Central nervous system: Confusion, drowsiness
Gastrointestinal: Diarrhea, nausea, vomiting
Respiratory: Hyperventilation
Other warnings/precautions:
• Self-medication (OTC use): Do not use on wounds, damaged skin, broken skin, or irritated skin. Stop use and call health care provider if irritation occurs or if conditions worsen, persist >7 days, or clears up then worsens again in a few days.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Cream, External, as salicylate:
Arthricream: 10% (90 g)
Asper-Flex: 10% (85 g [DSC]) [aspirin free, menthol free, odorless; contains cetyl alcohol, methylparaben, propylparaben, trolamine (triethanolamine)]
GoodSense Arthritis Relief: 10% (85 g) [odorless; contains cetyl alcohol, methylparaben, propylparaben, trolamine (triethanolamine)]
Mobisyl: 10% (100 g, 226.8 g) [odorless; contains cetyl alcohol, edetate (edta) sodium (tetrasodium), methylparaben, propylene glycol, propylparaben, trolamine (triethanolamine)]
Myoflex: 10% (57 g, 113 g)
Myoflex: 10% (113 g [DSC]) [odorless; contains cetyl alcohol, methylparaben, propylparaben, trolamine (triethanolamine)]
Generic: 10% (85 g [DSC])
Lotion, External, as salicylate:
Cydonol: (3840 mL [DSC])
Penetran: (113 g [DSC]) [aspirin free, menthol free; contains fd&c blue #1 (brilliant blue), methylparaben, polysorbate 80, quinoline yellow (d&c yellow #10)]
Penetran Plus: 2.5% (75 mL [DSC]) [aspirin free, capsaicin free, menthol free, salicylate free]
Tru-micin: 10% (100 mL [DSC]) [odorless; contains cetyl alcohol]
Ultracin T: 10% (120 mL) [paraben free; contains benzoic acid, cetearyl alcohol, propylene glycol]
Yes
Cream (Mobisyl External)
10% (per gram): $0.07
Cream (Myoflex External)
10% (per gram): $0.07
Lotion (Ultracin T External)
10% (per mL): $3.65
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Topical: Avoid contact with eyes and mucous membranes; do not apply to wounds, damaged skin, broken skin, or irritated skin. Massage into painful area until thoroughly absorbed. Do not bandage tightly or apply local heat (eg, heating pad) to the area being treated.
Topical: For external use only; avoid contact with eyes and mucous membranes. Do not apply to wounds or damaged skin. Do not bandage tightly or use with a heating pad.
Muscle/Joint pain: Temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, cramps, muscle strains, and sprains.
Myoflex may be confused with Mycelex
Biafine: Brand name for trolamine [multiple international markets], but also the brand name for a topical emulsion [U.S.]
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program by clicking on the “Launch drug interactions program” link above.
Warfarin: Salicylates (Topical) may enhance the anticoagulant effect of Warfarin. Risk C: Monitor therapy
Systemic absorption of salicylate occurs following topical administration of trolamine (Rabinowitz, 1984).
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