Version July 2025
Dietary supplement:
IM, IV: 0.25 to 2 mL.
Oral: General dosing guidelines: One tablet or capsule once or twice daily, refer to specific product labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
There are no dosage adjustments provided in the manufacturer's labeling.
Refer to adult dosing.
The following adverse drug reactions are derived from product labeling unless otherwise specified. Adverse effects are reported for the individual agents rather than for the combination product.
Frequency not defined:
Cardiovascular: Thrombosis (peripheral)
Dermatologic: Pruritus, transient skin rash
Gastrointestinal: Diarrhea
Hematologic & oncologic: Polycythemia vera
Hypersensitivity: Anaphylactic shock
Local: Pain at injection
Miscellaneous: Swelling
Postmarketing:
Dermatologic: Acne vulgaris, dermatological reaction, skin photosensitivity
Gastrointestinal: Abdominal pain, anorexia, nausea, vomiting
Hepatic: Increased liver enzymes
Hypersensitivity: Allergic sensitization, hypersensitivity reaction
Nervous system: Drowsiness, headache, paresthesia
Hypersensitivity to any component of the formulation.
Concerns related to adverse effects:
• Anaphylactogenesis: Use caution with parenteral thiamine; anaphylactogenesis may occur. An intradermal test dose is recommended prior to administration in patients with suspected thiamine sensitivity.
• Iron toxicity: For products containing iron: Severe iron toxicity may occur in overdose, particularly when ingested by children; iron is a leading cause of fatal poisoning in children; store out of children's reach and in child-resistant containers. Adult preparations may contain amounts of iron which should not be used in children.
Disease-related concerns:
• Pernicious anemia: For products containing folic acid: Doses of folic acid >0.1 mg/day may obscure pernicious anemia with continuing irreversible nerve damage progression.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Content varies depending on product used. For more detailed information on ingredients in these and other multivitamins, please refer to specific product labeling.
Yes
Capsules (Foltanx RF Oral)
3-90.314-2-35 mg (per each): $2.06
Capsules (L-Methylfolate-Algae-B12-B6 Oral)
3-90.314-2-35 mg (per each): $2.04
Capsules (Mynephron Oral)
1 mg (per each): $0.17
Capsules (Nufola Oral)
3.5-1-25-300 mg (per each): $0.64
Capsules (Renal Oral)
1 mg (per each): $0.67
Liquid (Actrivit Oral)
800-15-1 mg/15 mL (per mL): $0.03
Tablets (Cerefolin Oral)
6-1-50-5 mg (per each): $7.54
Tablets (Dexifol Oral)
5 mg (per each): $75.51
Tablets (Dialyvite 800 Oral)
0.8 mg (per each): $0.11
Tablets (Elfolate Plus Oral)
3-35-2 mg (per each): $2.16
Tablets (Folbic RF Oral)
1.13-25-2 mg (per each): $1.29
Tablets (Foltanx Oral)
3-35-2 mg (per each): $1.44
Tablets (Foltx Oral)
1.13-25-2 mg (per each): $2.47
Tablets (Metafolbic Oral)
6-1-50-5 mg (per each): $2.89
Tablets (Renatabs Oral)
1 mg (per each): $0.50
Wafer (Dialyvite 800 Oral)
0.8 mg (per each): $0.15
Wafer (Dialyvite 800 Plus D Oral)
800 mcg (per each): $0.18
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Injection: Administer IM or by slow IV push; high concentrations may be administered IV after dilution in NS.
Oral: May be taken with food to decrease stomach upset.
Dietary supplement:
Injection: Nutritional requirements in disorders requiring parenteral administration of vitamins (eg, preoperative/postoperative treatment; when requirements are increased as in alcoholism, severe burns, fever, GI disorders interfering with intake or absorption, increased metabolism, pregnancy, prolonged or wasting diseases, and where other deficiencies exist).
Oral: Medical food for the nutritional requirements of patients being treated for vitamin deficiencies.
Nephrocaps may be confused with Nephro-Calci
None known.
There are no known significant interactions.
Iron absorption is inhibited by eggs and milk.
Water soluble vitamins cross the placenta (IOM 1998). Refer to individual vitamins for additional information and specific requirements during pregnancy.
Refer to individual vitamins for additional information and specific requirements in nursing women.
May be taken with food to decrease stomach upset.
