Topical infection, prevention: Topical: Apply a small amount to the affected area 1 to 3 times daily.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
(For additional information see "Bacitracin and polymyxin B (topical): Pediatric drug information")
Infection, prevention: Infants, Children, and Adolescents: Topical ointment: Apply to the affected area 1 to 3 times daily; may cover with sterile bandage if needed
See individual agents.
OTC labeling: When used for self-medication, do not use if hypersensitive to bacitracin, polymyxin B, or any component of the formulation.
Concerns related to adverse effects:
• Anaphylaxis: Use with caution in patients who have been previously exposed to bacitracin; anaphylactic reactions have occurred on repeat exposure (Elsner 1990; Farley 1995).
Other warnings/precautions:
• Self-medication (OTC use): When used for self-medication (OTC), do not use in the eyes, over large areas of the body, or for longer than 1 week unless directed by health care provider. Discontinue use and notify health care provider prior to use for deep puncture wounds, bites, or serious burns, if condition persists or worsens, or if rash or other allergic reaction occurs.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Ointment, External:
Double Antibiotic: Bacitracin 500 units and polymyxin B 10,000 units per g (1 ea [DSC], 14.17 g [DSC], 14.2 g, 28.35 g [DSC], 28.4 g)
FT Double Antibiotic: Bacitracin 500 units and polymyxin B 10,000 units per g (28.4 g)
Polysporin: Bacitracin 500 units and polymyxin B 10,000 units per g (1 ea, 14.2 g, 28.3 g)
Yes
Ointment (Polysporin External)
500-10000 units/g (per gram): $0.42
500-10000 units/g (per each): $0.26
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Topical: For topical use only; do not use in the eyes or over large areas of the body. Clean affected area prior to application. Apply a small amount of product (an amount equal to the surface area of the tip of a finger); may cover with sterile bandage.
Topical: Cleanse affected area before application. Apply a small amount of product (an amount equal to the surface area of the tip of a finger); may be covered by a sterile bandage if necessary. Do not use topical ointment in the eyes or over large areas of the body; avoid contact of tube tip with skin.
Topical infection prevention: Prevention of infection in minor cuts, scrapes, or burns.
Refer to individual components.
There are no known significant interactions.
Refer to individual monographs.
Refer to individual monographs.
See individual agents.
See individual agents.
Absorption: Insignificant from intact skin or mucous membrane