Conjunctivitis: Limited data available: Infants, Children, and Adolescents: Ophthalmic: Apply to affected eye(s) 4 times daily (Giggliotti 1984; Wald 1997)
There are no dosage adjustments provided in the manufacturer’s labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
(For additional information see "Bacitracin and polymyxin B (ophthalmic): Drug information")
Superficial ocular infections: Ophthalmic: Apply a thin strip to affected eye(s) every 3 to 4 hours for 7 to 10 days.
There are no dosage adjustments provided in the manufacturer’s labeling.
There are no dosage adjustments provided in the manufacturer’s labeling.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. See individual agents. Frequency not defined.
Hypersensitivity: Anaphylaxis
Ophthalmic: Burning sensation of eyes, conjunctival erythema, eye pruritus, swelling of eye
Hypersensitivity to bacitracin, polymyxin B, or any component of the formulation
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Ointment, Ophthalmic:
Polycin: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
Generic: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g)
Ointment, Ophthalmic [preservative free]:
AK-Poly-Bac: Bacitracin 500 units and polymyxin B 10,000 units per g (3.5 g [DSC])
Yes
Ointment (Polycin Ophthalmic)
500-10000 units/g (per gram): $7.46
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Ophthalmic: Wash hands before use; avoid contact of tube tip with skin or eye
Ophthalmic: For topical ophthalmic use only; apply directly to conjunctival sac; avoid gross contamination of ointment during application.
Treatment of superficial infections involving the conjunctiva and/or cornea caused by susceptible organisms (FDA approved in adults)
None known.
There are no known significant interactions.
Animal reproduction studies have not been conducted with this combination.
See individual agents.
See individual agents.
Absorption: Insignificant from intact skin or mucous membrane
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