Version May 2024
Topical infection prevention: Topical: Apply 1 to 3 times/day to infected area; may cover with sterile bandage if necessary.
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
Refer to adult dosing.
(For additional information see "Bacitracin, neomycin, and polymyxin B (topical): Pediatric drug information")
Prevention of infection: Infants, Children, and Adolescents: Topical: Apply to affected area 1 to 3 times daily
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
There are no dosage adjustments provided in the manufacturer’s labeling. However, dosage adjustment unlikely due to low systemic absorption.
The following adverse drug reactions and incidences are derived from product labeling unless otherwise specified. Frequency not defined.
Dermatologic: Reddening, allergic contact dermatitis
Local: Itching, failure to heal, swelling, irritation
Miscellaneous: Anaphylaxis
Hypersensitivity to bacitracin, neomycin, polymyxin B, or any component of the formulation.
Dosage form specific issues:
• Topical ointment: When used for self-medication (OTC use), patients should notify healthcare provider if needed for >1 week. Should not be used for self-medication on deep or puncture wounds, animal bites, or serious burns. Not for application to large areas of the body.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Ointment, External:
Curad Triple Antibiotic: bacitracin, neomycin, and polymyxin B (1 ea [DSC])
Medi-First Triple Antibiotic: bacitracin, neomycin, and polymyxin B (1 ea)
Neosporin Original: bacitracin, neomycin, and polymyxin B (1 ea, 14.2 g, 28.3 g)
Triple Antibiotic: bacitracin, neomycin, and polymyxin B (1 ea, 144 ea, 9.35 g [DSC], 9.4 g, 14 g, 14.2 g, 15 g, 28 g, 28.4 g, 30 g)
Triple Antibiotic First Aid: bacitracin, neomycin, and polymyxin B (1 ea [DSC])
Yes
Ointment (Neosporin Original External)
3.5-400-5000 (per each): $0.25
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Topical: For external use only. Clean affected area prior to application. Apply amount equal to the surface area of the tip of the finger. Do not use topical ointment in the eyes or over large areas of the body; avoid contact of tube tip with skin.
Topical: Clean the affected area prior to use. Apply a small amount of product (an amount equal to the surface area of the tip of a finger); may cover with sterile bandage.
Topical infection prevention: Prevention of infection in minor cuts, scrapes, or burns.
None known.
There are no known significant interactions.
Animal reproduction studies have not been conducted with this combination.
It is not known if bacitracin, neomycin, or polymyxin B is excreted into breast milk.
See individual agents.
See individual agents.
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