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Balsam peru and castor oil: Drug information

Balsam peru and castor oil: Drug information
(For additional information see "Balsam peru and castor oil: Patient drug information")

For abbreviations, symbols, and age group definitions used in Lexicomp (show table)
Brand Names: US
  • B & C;
  • BPCO;
  • Dermulcera [DSC];
  • Venelex
Pharmacologic Category
  • Protectant, Topical
Dosing: Adult
Ulcer/wound management

Ulcer/wound management: Topical: Apply thin film twice daily or as often as necessary.

Dosing: Kidney Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.

Dosing: Hepatic Impairment: Adult

There are no dosage adjustments provided in the manufacturer's labeling. However, dosage adjustment unlikely due to low systemic absorption.

Dosing: Older Adult

Refer to adult dosing.

Adverse Reactions

See Castor Oil monograph.

Contraindications

Hypersensitivity to balsam peru, castor oil, petrolatum, or any component of the formulation.

Warnings/Precautions

Disease-related concerns:

• Hemoglobin deficiency: Wound healing may be retarded in the presence of hemoglobin deficiency.

• Zinc deficiency: Wound healing may be retarded in the presence of zinc deficiency.

Other warnings/precautions:

• Appropriate use: For external use only; avoid contact with eyes. Do not apply to fresh arterial clots.

Dosage Forms: US

Excipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product

Ointment, External:

B & C: (56.7 g, 60 g)

BPCO: (60 g)

Dermulcera: (60 g [DSC])

Venelex: Balsam peru 87 mg and castor oil 788 mg per gram (5 g, 28.35 g, 56.7 g)

Generic: (60 g)

Generic Equivalent Available: US

Yes

Pricing: US

Aerosol (Proderm External)

650-72.5 mg/0.82 mL (113.4 g): $16.40

Disclaimer: The pricing data provide a representative AWP and/or AAWP price from a single manufacturer of the brand and/or generic product, respectively. The pricing data should be used for benchmarking purposes only, and as such should not be used to set or adjudicate any prices for reimbursement or purchasing functions. Pricing data is updated monthly.

Administration: Adult

Topical: Do not apply on fresh arterial clots. Apply a thin film over the area being treated. May be used with appropriate dressing if needed, or wound may be left unbandaged. To remove, wash gently with appropriate wound cleanser.

Use: Labeled Indications

Ulcer/wound management: Promotes wound healing by deodorizing and protectively covering chronic or acute wounds and dermal ulcers (eg, pressure ulcers, venous stasis ulcers, diabetic ulcers, first-/second-degree burns, surgical wounds, traumatic wound, superficial wounds, ulcers resulting from arterial insufficiency, ulcers resulting from grafted wound/donor sites).

Metabolism/Transport Effects

None known.

Drug Interactions

Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program by clicking on the “Launch drug interactions program” link above.

Polyethylene Glycol-Electrolyte Solution: Laxatives (Stimulant) may enhance the adverse/toxic effect of Polyethylene Glycol-Electrolyte Solution. Specifically, the risk of colonic mucosal aphthous ulcerations may be increased. Management: Consider avoiding this combination due to a potential for increased risk of colonic mucosal aphthous ulcerations. Risk D: Consider therapy modification

Sodium Sulfate: Laxatives (Stimulant) may enhance the adverse/toxic effect of Sodium Sulfate. Specifically, the risk of mucosal ulceration or ischemic colitis may be increased. Risk X: Avoid combination

Mechanism of Action

Balsam peru stimulates circulation at the wound site and may be mildly bactericidal; castor oil improves epithelialization, acts as a protectant covering and helps reduce pain

Brand Names: International
International Brand Names by Country
For country code abbreviations (show table)

  • (PR) Puerto Rico: Venelex
  1. B&C Ointment (balsam peru and castor oil) [prescribing information]. Alpharetta, GA: Laser Pharmaceuticals LLC; January 2021.
  2. BPCO Ointment (balsam peru and castor oil) [prescribing information]. Pulaski, TN: AvKARE Inc; October 2019.
  3. Dermulcera (balsam peru and castor oil) [prescribing information]. Alpharetta, GA: Canton Laboratories LLC; May 2019.
  4. Venelex (balsam peru and castor oil) [prescribing information]. Miami, FL: Stratus Pharmaceuticals Inc; October 2021.
Topic 103782 Version 60.0

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