Dynamic International Prognostic Scoring System (DIPSS) Plus for primary myelofibrosis

Survival data of 428 patients with primary myelofibrosis evaluated within one year of their diagnosis and stratified by their Dynamic International Prognostic Scoring System (DIPSS) + karyotype + platelet count + transfusion status prognostic scores. Low risk, zero adverse points; n = 46; median survival, approximately 180 months. Intermediate-1 risk, one adverse point; n = 114; median survival, approximately 80 months. Intermediate-2 risk, two or three adverse points; n = 177; median survival, approximately 35 months. High risk, four to six adverse points; n = 91; median survival, approximately 16 months. The p value refers to survival differences between risk groups.