Causes of small bowel bleeding

Common causes		Rare causes
Under age 40 years	Over age 40 years	Rare causes
Inflammatory bowel disease Meckel's diverticulum Dieulafoy lesions Neoplasia Polyposis syndromes	NSAID ulcers Angioectasia Dieulafoy lesions Neoplasia	Immunoglobulin A vasculitis (Henoch-Schöenlein purpura) Small bowel varices and/or portal hypertensive enteropathy Amyloidosis Blue rubber bleb nevus syndrome Pseudoxanthoma elasticum Hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu syndrome) Kaposi sarcoma with AIDS Plummer-Vinson syndrome Ehlers-Danlos syndrome Inherited polyposis syndromes (FAP, Peutz-Jeghers) Malignant atrophic papulosis Hematobilia Aortoenteric fistula Hemosuccus entericus

FAP: familial adenomatous polyposis; NSAID: nonsteroidal anti-inflammatory drug.

Adapted by permission from Macmillan Publishers Ltd: American Journal of Gastroenterology. Gerson LB, Fidler JL, Cave DR, Leighton JA. ACG Clinical Guideline: Diagnosis and Management of Small Bowel Bleeding. Am J Gastroenterol 2015; 110:1265. Copyright © 2015. www.nature.com/ajg.

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Causes of small bowel bleeding