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Key components of the renin-angiotensin system

Key components of the renin-angiotensin system
Schematic illustration of the renin-angiotensin system. Receptors are shown in boxes, and enzymes are shown next to their respective arrows.
ACE: angiotensin-converting enzyme; Agt: angiotensinogen; Ang: angiotensin; APA: aminopeptidase A; AT1R: angiotensin type 1 receptor; AT2R: angiotensin type 2 receptor; MasR: Mas receptor; MrgD: Mas-related G protein-coupled receptor; PRR: (pro)renin receptor.
Reproduced from: Carey RM. The intrarenal renin-angiotensin system in hypertension. Adv Chronic Kidney Dis. 2015; 22:204. Illustration used with the permission of Elsevier Inc. All rights reserved.
Graphic 105360 Version 5.0

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