Version May 2024
| Pediculicide* | Mechanism of action | Age group | Regimen | Precautions/side effects |
| Benzyl alcohol | Asphyxiation | ≥6 months | Leave on hair for 10 minutes, then rinse; repeat after 7 days | Skin and eye irritation, transient skin numbness |
| Ivermectin | Neurotoxin | ≥6 months | Leave on hair for 10 minutes, then rinse | Skin or eye irritation |
| Malathion | Neurotoxin | ≥6 years; contraindicated in children under 2 years; safety has not been established in children 2 to 6 years | Leave on hair for 8 to 12 hours, then wash with a nonmedicated shampoo; a single application may be effective; repeat in 7 to 9 days if live lice are seen | Malodorous, flammable, skin irritation, theoretical risk for respiratory depression if ingested |
| Permethrin (1%) | Neurotoxin | ≥2 months | Leave on hair for 10 minutes, then rinse; repeat on day 9 | Skin irritation; pyrethrins may induce breathing difficulties in patients with ragweed allergy; avoid permethrin in patients with chrysanthemum allergy |
| Pyrethrins and piperonyl butoxide | Neurotoxin | ≥2 years | Leave on hair for 10 minutes, then rinse; repeat on day 9 | Skin irritation |
| Spinosad | Neurotoxin | ≥6 months | Leave on hair for 10 minutes, then rinse; repeat in 7 days if live lice remain | Skin irritation |
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