Residual kidney function in hemodialysis patients (Kru)

10,080 is the number of minutes in a week.
Equation 1 expresses weekly intermittent dialyzer clearance as continuous clearance.
Equation 2 incorporates S into a variable volume model that accounts for ultrafiltration and for residual kidney function.

S: stdKt/V assuming constant volume; stdKt/V: standard Kt/V; N: number of dialyses per week; U_f: weekly ultrafiltration volume in mL; V: volume of urea distribution in mL; Kru: residual native kidney clearance of urea in mL/min; F: number of sessions per week.

From: National Kidney Foundation. KDOQI Clinical Practice Guideline for hemodialysis adequacy: 2015 update. Am J Kidney Dis 2015; 66:884.

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