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Probability that an adolescent with symptomatic anovulatory symptoms will have ongoing menstrual abnormality

Probability that an adolescent with symptomatic anovulatory symptoms will have ongoing menstrual abnormality
The "All symptomatic anovulation" curve is derived from the data of Southam and Richart[1]. The "Hyperandrogenic" and "Non-hyperandrogenic" curves are hypothetical and based on data discussed in UpToDate. Hyperandrogenic cases are predominantly composed of physiologic anovulation and PCOS, with PCOS persisting, while non-hyperandrogenic cases are composed of physiologic anovulation and hypogonadal cases, with hypogonadal cases persisting.
PCOS: polycystic ovary syndrome.
Reference:
  1. Southam AL, Richart RM. The prognosis for adolescents with menstrual abnormalities. Am J Obstet Gynecol 1966; 94:637.

Figure provided by Dr. Robert Rosenfield, and updated from research previously published in: Rosenfield RL. The diagnosis of polycystic ovary syndrome in adolescents. Pediatrics 2015; 136:1154.

Graphic 107841 Version 10.0

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