BED: biologic equivalent dose; CRT: chemoradiation; FU: fluorouracil; Gy: Gray; PDT: photodynamic therapy; SBRT: stereotactic body radiation therapy.
* For patients with locally advanced initially unresectable cholangiocarcinoma who are treated with neoadjuvant therapy, the role of orthotopic liver transplantation is controversial.
¶ Solitary site of unresectable disease, able to tolerate chemoradiation.