Version May 2024
The following adverse drug reactions are derived from product labeling unless otherwise specified. Also see Dextrose and Sodium Chloride monographs.
Postmarketing:
Dermatologic: Injection site blister formation, pruritus, skin rash
Endocrine & metabolic: Hyperchloremic metabolic acidosis, hyperglycemia, hypernatremia, hypervolemia, hyponatremia
Hypersensitivity: Anaphylaxis, hypersensitivity reaction
Local: Injection site phlebitis, pain at injection site, venous thrombosis at injection site
Nervous system: Chills, encephalopathy (hyponatremic)
Miscellaneous: Febrile reaction, fever
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, Intravenous:
Generic: Dextrose 10% and sodium chloride 0.2% (250 mL); Dextrose 10% and sodium chloride 0.45% (1000 mL); Dextrose 2.5% and sodium chloride 0.45% (1000 mL); Dextrose 5% and sodium chloride 0.2% (250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.33% (500 mL); Dextrose 5% and sodium chloride 0.45% (500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.9% (500 mL, 1000 mL)
Solution, Intravenous [preservative free]:
Generic: Dextrose 2.5% and sodium chloride 0.45% (1000 mL); Dextrose 5% and sodium chloride 0.2% (250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.3% (250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.45% (250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.9% (500 mL, 1000 mL)
Yes
Solution (Dextrose-Sodium Chloride Intravenous)
2.5-0.45% (per mL): $0.01
5-0.225% (per mL): $0.01
5-0.3% (per mL): $0.01
5-0.45% (per mL): $0.01
5-0.9% (per mL): $0.01
Disclaimer: A representative AWP (Average Wholesale Price) price or price range is provided as reference price only. A range is provided when more than one manufacturer's AWP price is available and uses the low and high price reported by the manufacturers to determine the range. The pricing data should be used for benchmarking purposes only, and as such should not be used alone to set or adjudicate any prices for reimbursement or purchasing functions or considered to be an exact price for a single product and/or manufacturer. Medi-Span expressly disclaims all warranties of any kind or nature, whether express or implied, and assumes no liability with respect to accuracy of price or price range data published in its solutions. In no event shall Medi-Span be liable for special, indirect, incidental, or consequential damages arising from use of price or price range data. Pricing data is updated monthly.
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Solution, Intravenous:
Generic: 10-0.9 % (1000 mL); 3.3-0.3 % (50 mL, 100 mL, 250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.2% (250 mL, 500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.45% (500 mL, 1000 mL); Dextrose 5% and sodium chloride 0.9% (250 mL, 500 mL, 1000 mL)
Source of calories, sodium chloride, and water for hydration
Inappropriate use of low sodium or sodium-free intravenous fluids (eg D5W, hypotonic saline) in pediatric patients can lead to significant morbidity and mortality due to hyponatremia (ISMP 2009)
None known.
Note: Interacting drugs may not be individually listed below if they are part of a group interaction (eg, individual drugs within “CYP3A4 Inducers [Strong]” are NOT listed). For a complete list of drug interactions by individual drug name and detailed management recommendations, use the Lexicomp drug interactions program by clicking on the “Launch drug interactions program” link above.
Lithium: Sodium Chloride may increase the excretion of Lithium. Risk C: Monitor therapy
Tolvaptan: Sodium Chloride may enhance the adverse/toxic effect of Tolvaptan. Specifically, Hypertonic Saline may increase the risk for too rapid of an increase in serum sodium concentrations. Management: This interaction is specific to hypertonic saline. Avoid concurrent use of hypertonic saline with tolvaptan. Risk X: Avoid combination
آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
