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The Deauville score for interpreting FDG-PET in lymphoma

The Deauville score for interpreting FDG-PET in lymphoma
Score Findings
1 No uptake
2 Uptake ≤ mediastinal blood pool
3 Uptake > mediastinal blood pool but ≤ liver
4 Uptake moderately more than liver uptake, at any site
5 Uptake markedly higher than liver (ie, 2 to 3 times the maximum SUV in the liver) and/or new lesions
X New areas of uptake unlikely to be related to lymphoma

The Deauville score (also known as the 5-point scale) is a purely visual method of standardizing the interpretation of post-treatment PET scans for primary nodal lymphoma allowing for the comparison of scans performed using different machines at different centers. The Deauville score uses a patient's FDG uptake in the mediastinal blood pool and liver as an internal control. FDG uptake is always present in these 2 sites, with higher levels consistently seen in the liver. The Deauville score interprets FDG avidity of suspected disease (most intense uptake in a site of initial disease) in relation to FDG uptake in these 2 locations.

NOTE: If mediastinal blood pool activity is equal to or greater than activity in the liver, then the uptake within the lesion should be compared with that in the liver (uptake lesion < liver score 2; lesion = liver score 3).
FDG: fludeoxyglucose; PET: positron emission tomography; SUV: standardized uptake value.
Reprinted by permission from: Springer: European Journal of Nuclear Medicine and Molecular Imaging. Barrington SF, Qian W, Somer EJ, et al. Concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma. Eur J Nucl Med Mol Imaging 2010; 37:1824. Copyright © 2010. https://link.springer.com/journal/259.
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