Introduction — This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.
The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.
Links to related guidelines are provided separately. (See "Society guideline links: Anaphylaxis" and "Society guideline links: Perioperative anaphylaxis".)
International
●International Suspected Perioperative Allergy Reaction (ISPAR) Group: Narrative and consensus recommendations for the management of a surgical patient with a label of penicillin allergy (2019)
●International Consensus (ICON): Position paper on drug allergy (2014)
●World Allergy Organization (WAO) Special Committee on Drug Allergy: A statement on hypersensitivity reactions to non beta-lactam antimicrobial agents (2013)
Canada
●Choosing Wisely Canada: Don't order non-beta lactam antibiotics in patients with a history of penicillin allergy, without an appropriate evaluation (2021)
●Canadian Paediatric Society (CPS): Practice point on beta-lactam allergy in the paediatric population (2020)
United States
●American Academy of Allergy, Asthma, and Immunology (AAAAI) and American College of Allergy, Asthma, and Immunology (ACAAI): Practice parameter on drug allergy, update (2022)
●AAAAI: A work group report on the role of aspirin desensitization followed by oral aspirin therapy in managing patients with aspirin-exacerbated respiratory disease (2021)
●Centers for Disease Control and Prevention (CDC): Sexually transmitted infections treatment guidelines – Managing persons who have a history of penicillin allergy (2021)
●AAAAI: Practical guidance for the evaluation and management of drug hypersensitivity – Specific drugs (2020)
●Society of Dermatology Hospitalists (SDH): Supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults (2020)
●European Academy of Allergy and Clinical Immunology (EAACI) and AAAAI: PRACTALL document on precision medicine in allergic disease – Food allergy, drug allergy, and anaphylaxis (2017)
Europe
●European Academy of Allergy and Clinical Immunology (EAACI): Task force report on allergy to beta-lactams in children – Clinical entities and diagnostic procedures (2021)
●EAACI: Position paper for diagnosis and management of NSAID-exacerbated respiratory disease (N-ERD) (2019)
●EAACI: Position paper on how to classify cutaneous manifestations of drug hypersensitivity (2019)
●EAACI: Towards a more precise diagnosis of hypersensitivity to beta‐lactams – A position paper (2019)
●EAACI/European Network for Drug Allergy (ENDA): Position paper for diagnosis and management of hypersensitivity reactions to non-steroidal anti-inflammatory drugs (NSAIDs) in children and adolescents (2018)
●EAACI and American Academy of Allergy, Asthma, and Immunology (AAAAI): PRACTALL document on precision medicine in allergic disease – Food allergy, drug allergy, and anaphylaxis (2017)
●ENDA/EAACI: Position paper on drug allergy passport and other documentation for patients with drug hypersensitivity (2016)
●ENDA/EAACI: Position paper on in vitro tests for drug hypersensitivity reactions (2016)
●ENDA/EAACI: Report from the pediatric task force on drug hypersensitivity in children (2016)
●ENDA/EAACI: Position paper on drug hypersensitivity in clonal mast cell disorders (2015)
●EAACI: Position paper on desensitization in delayed drug hypersensitivity reactions (2013)
●ENDA/EAACI: Position paper on skin test concentrations for systemically administered drugs (2013)
United Kingdom
●Primary Care Dermatology Society (PCDS): Drug rashes – Mild to moderate (updated 2021)
●PCDS: Drug rashes – Severe (updated 2021)
●British Association of Dermatologists (BAD): Guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in children and young people, 2018 (published 2019)
●BAD: UK guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults (2016)
●British Society for Allergy and Clinical Immunology (BSACI): Guideline for the management of allergy to penicillins and other beta-lactams (2015)
●National Institute for Health and Care Excellence (NICE): Quality standard on drug allergy (2015)
●NICE: Clinical guideline on drug allergy – Diagnosis and management (2014)
●Royal College of Paediatrics and Child Health (RCPCH): Allergy care pathways for children – Drug allergy (2011)
Australia–New Zealand
●Australasian Society of Clinical Immunology and Allergy (ASCIA): Consensus statement for the assessment of suspected allergy to penicillin antibiotics (2020)
●ASCIA: Antibiotic allergy clinical update (2014)
