Definition of minimum alveolar concentration (MAC) values

MAC level	Effect
0.3 MAC	MAC_awake (MAC value below this will allow the patient to become conscious)
1 MAC	End-tidal concentration of anesthetic agent necessary to prevent movement in response to a surgical stimulus in 50% of patients
1.5 MAC	MAC value where 90% of patients will not move in response to a surgical stimulus
2.0 MAC	MAC-BAR (MAC value required to block autonomic responses to a surgical stimulus in 50% of patients)

MAC: minimum alveolar concentration; a value of 1.0 MAC is the concentration of an inhalation anesthetic agent in the alveoli required to prevent movement to a surgical stimulus in 50% of patients.

Graphic 109424 Version 2.0

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