Cranial imaging in an infant with severe congenital Zika syndrome

Imaging findings of an infant with severe CZS.
(A) Three-dimensional CT reconstruction showing classic phenotypic pattern of fetal skull collapse with overlapping cranial sutures and prominent occipital protrusion.
(B) T2-weighted MRI showing simplified gyral pattern with a lissencephalic appearance of the brain.

CZS: congenital Zika syndrome; CT: computed tomography; MRI: magnetic resonance imaging.

From: Pool KL, Adachi K, Karnezis S, et al. Association between neonatal neuroimaging and clinical outcomes in Zika-exposed infants from Rio de Janeiro, Brazil. JAMA Netw Open 2019; 2:e198124. Available at: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2740070. Copyright © 2019 The Authors. Reproduced under the terms of the Creative Commons CC-BY License.

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Cranial imaging in an infant with severe congenital Zika syndrome