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Pramipexole: Patient drug information

Pramipexole: Patient drug information

(For additional information see "Pramipexole: Drug information")

You must carefully read the "Consumer Information Use and Disclaimer" below in order to understand and correctly use this information.

Brand Names: US
  • Mirapex ER;
  • Mirapex [DSC]
Brand Names: Canada
  • ACT Pramipexole;
  • APO-Pramipexole;
  • Auro-Pramipexole;
  • Mirapex;
  • RATIO-Pramipexole;
  • SANDOZ Pramipexole
What is this drug used for?
  • It is used to treat Parkinson's disease.
  • It is used to treat restless leg syndrome.
  • It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take this drug?
  • If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have kidney disease.
  • If you are taking another drug that has the same drug in it.
  • This is not a list of all drugs or health problems that interact with this drug.
  • Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take this drug?
  • All products:
  • Tell all of your health care providers that you take this drug. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Check your blood pressure as you have been told.
  • Do not stop this drug without talking to your doctor. When you stop this drug, you may have signs of withdrawal. If you need to stop this drug, follow how to stop it as your doctor has told you. Call your doctor right away if you have any of these signs when lowering the dose or stopping this drug: fever, confusion, severe muscle stiffness, not caring about things, anxiety, depression, feeling tired, trouble sleeping, sweating, or pain.
  • Avoid drinking alcohol while taking this drug.
  • Talk with your doctor before you use marijuana, other forms of cannabis, or prescription or OTC drugs that may slow your actions.
  • Neuroleptic malignant syndrome (NMS) is a severe and sometimes deadly health problem that has happened when drugs like this one were stopped all of a sudden. NMS has also happened when the dose was lowered. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, severe headache, confusion, change in thinking, fast or abnormal heartbeat, or are sweating a lot.
  • If you are 65 or older, use this drug with care. You could have more side effects.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
  • Extended-release tablets:
  • You may see something that looks like the tablet in your stool. If this happens, talk with your doctor.
What are some side effects that I need to call my doctor about right away?
  • WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
  • For all uses of this drug:
  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Strong urges that are hard to control (such as eating, gambling, sex, or spending money).
  • Fever.
  • Feeling confused.
  • Muscle stiffness.
  • Passing urine more often.
  • Very bad dizziness or passing out.
  • Sweating a lot.
  • Shortness of breath, a big weight gain, or swelling in the arms or legs.
  • Change in eyesight.
  • Trouble controlling body movements that is new or worse.
  • Trouble moving around.
  • Hallucinations (seeing or hearing things that are not there).
  • Memory problems or loss.
  • Muscle pain or weakness.
  • Mental, mood, or behavior changes that are new or worse.
  • Some people have fallen asleep during activities like driving, eating, or talking. Some people did not feel sleepy and felt alert right before falling asleep. This has happened up to 1 year after this drug was started. If you fall asleep during activities, do not drive or do other tasks or actions that call for you to be alert while you take this drug. Call your doctor right away if this happens or you feel very sleepy.
  • Some people have had changes in posture that cannot be controlled. These may include neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand, or walk. Changes in posture may happen several months after you start this drug or after an increase in dose. Call your doctor if you have any changes in posture.
  • Restless leg syndrome:
  • For restless leg syndrome, tell your doctor if your signs become worse or start earlier in the day.
What are some other side effects of this drug?
  • All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
  • Headache.
  • Upset stomach.
  • Diarrhea or constipation.
  • Decreased appetite.
  • Trouble sleeping.
  • Feeling dizzy, sleepy, tired, or weak.
  • Dry mouth.
  • Strange or odd dreams.
  • Muscle spasm.
  • Weight loss.
  • Stuffy nose.
  • Flu-like signs.
  • These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
  • You may report side effects to your national health agency.
How is this drug best taken?
  • Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
  • All products:
  • Take with or without food. Take with food if it causes an upset stomach.
  • Keep taking this drug as you have been told by your doctor or other health care provider, even if you feel well.
  • Regular-release tablets:
  • For restless leg syndrome, take this drug 2 to 3 hours before bedtime.
  • Extended-release tablets:
  • Swallow whole. Do not chew, break, or crush.
What do I do if I miss a dose?
  • Regular-release tablets:
  • Skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • If you miss taking this drug for a few days in a row, call your doctor before you start taking it again.
  • Extended-release tablets:
  • Take a missed dose as soon as you think about it.
  • If it has been 12 hours or more since the missed dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • If you miss taking this drug for a few days in a row, call your doctor before you start taking it again.
How do I store and/or throw out this drug?
  • Store at room temperature protected from light. Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
General drug facts
  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. If you have any questions about this drug, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Last Reviewed Date2021-08-05
Consumer Information Use and Disclaimer
  • This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms.
  • © 2024 UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.
Topic 10988 Version 180.0

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