D-penicillamine-induced elastosis perforans serpiginosa

This image shows thickened elastic fibers in the process of transepidermal elimination. The papillary dermal elastic fibers otherwise appear normal on routine stained sections.

Reproduced with permission from: Nguyen CV, Curry JL, Chu EY. Cutaneous toxiticies of drugs. In: Lever's Dermatopathology: Histopathology of the Skin, 12th ed, Elder DE (Ed), Lippincott Williams & Wilkins 2022. Copyright © 2022 Wolters Kluwer Health, Inc.

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D-penicillamine-induced elastosis perforans serpiginosa