Society guideline links: Infections in asplenic patients

Introduction — 

This topic includes links to society and government-sponsored guidelines from selected countries and regions around the world. We will update these links periodically; newer versions of some guidelines may be available on each society's website. Some societies may require users to log in to access their guidelines.

The recommendations in the following guidelines may vary from those that appear in UpToDate topic reviews. Readers who are looking for UpToDate topic reviews should use the UpToDate search box to find the relevant content.

Links to related guidelines are provided separately:

●(See "Society guideline links: Immunizations in children and adolescents".)

●(See "Society guideline links: Immunizations in adults".)

●(See "Society guideline links: Meningococcal disease".)

●(See "Society guideline links: Prevention of meningococcal disease".)

●(See "Society guideline links: Pneumococcal vaccination".)

●(See "Society guideline links: Haemophilus influenzae type b vaccination".)

●(See "Society guideline links: Sickle cell disease and thalassemias".)

Canada

●Public Health Agency of Canada (PHAC): Canadian Immunization Guide – Immunization of persons with chronic diseases: Asplenia or hyposplenia (2022, updated 2024)

●Canadian Pediatric Society (CPS): Position statement on preventing and treating infections in children with asplenia or hyposplenia (2019)

United States

●Advisory Committee on Immunization Practices (ACIP): Adult immunization schedule – Recommendations for ages 19 years or older, United States (2025)

●ACIP: Child and adolescent immunization schedule – Recommendations for ages 18 years or younger, United States (2025)

●American Academy of Pediatrics (AAP): Red Book – Immunization and other considerations in immunocompromised children: Asplenia and functional asplenia (2024)

●ACIP: General best practice guidelines for immunization – Altered Immunocompetence: Conditions or drugs that might cause immunodeficiencies – Anatomic or functional asplenia (2023)

United Kingdom

●British Society for Haematology (BSH): Guideline for prevention and treatment of infection in patients with an absent or hypofunctional spleen (2024)

●UK Health and Security and Agency (UKHSA): The Green Book – Immunisation against infectious disease: Immunisation of individuals with underlying medical conditions - Asplenia (absent or dysfunctional spleen) (2013, updated 2020)

Australia–New Zealand

●Australian Technical Advisory Group on Immunisation (ATAGI): The Australian Immunisation Handbook – Vaccination for people who are immunocompromised: People with functional or anatomical asplenia (2024)

●Spleen Australia: Medical recommendations on vaccines for adults (>18 years) with asplenia/hyposplenism who have not previously been vaccinated (2023)

●Spleen Australia: Paediatric guidelines age 0 to 18 years on asplenia/hyposplenism (2023)

●Spleen Australia: Guidelines for the prevention of sepsis in patients with asplenia and hyposplenism in Australia and New Zealand (2017)