Erythema nodosum

(A) Septal panniculitis with mixed inflammatory infiltrate containing histiocytes, lymphocytes, neutrophils, and eosinophils.
(B) Meischer's radial granulomas (small, nodular aggregates of histiocytes surrounding "banana-shaped" extracellular clefts). Neutrophils surround the granulomas.
(C) Multinucleated giant cells (a feature of late-stage erythema nodosum).
(D) Septal inflammation with eosinophils, sparing the adipocytes.