Classification of antibody-mediated rejection in the pancreas allograft

Antibody-mediated rejection	Morphological tissue injury
Grade I (mild)	Well-preserved architecture with mild interacinar inflammation and rare acinar cell damage
Grade II (moderate)	Overall preserved architecture with interacinar infiltrates with multi-acinar cell damage/dropout, extravasation of red blood cells, and interacinar capillaritis
Grade III (severe)	Architectural disarray, interstitial hemorrhage, multifocal parenchymal necrosis, arterial and venous wall necrosis and thrombosis

Adapted from: Drachenberg CB, Torrealba JR, Nankivell BJ, et al. Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schema. Am J Transplant 2011; 11:1792. http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1600-6143.2011.03670.x/abstract. Copyright © 2011 The American Society of Transplantation and the American Society of Transplant Surgeons. Reproduced with permission of John Wiley & Sons Inc. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (http://onlinelibrary.wiley.com).

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Classification of antibody-mediated rejection in the pancreas allograft