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Tumors of the renal pelvis and ureter TNM staging AJCC UICC 8th edition

Tumors of the renal pelvis and ureter TNM staging AJCC UICC 8th edition
Primary tumor (T)
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Ta Papillary noninvasive carcinoma
Tis Carcinoma in situ
T1 Tumor invades subepithelial connective tissue
T2 Tumor invades the muscularis
T3 For renal pelvis only: Tumor invades beyond muscularis into peripelvic fat or into the renal parenchyma.
For ureter only: Tumor invades beyond muscularis into periureteric fat.
T4 Tumor invades adjacent organs, or through the kidney into the perinephric fat
Regional lymph nodes (N)
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis ≤2 cm in greatest dimension, in a single lymph node
N2 Metastasis >2 cm, in a single lymph node; or multiple lymph nodes
Distant metastasis (M)
M category M criteria
M0 No distant metastasis
M1 Distant metastasis
Prognostic stage groups
When T is... And N is... And M is... Then the stage group is...
Ta N0 M0 0a
Tis N0 M0 0is
T1 N0 M0 I
T2 N0 M0 II
T3 N0 M0 III
T4 NX, N0 M0 IV
Any T N1 M0 IV
Any T N2 M0 IV
Any T Any N M1 IV
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: Union for International Cancer Control.
Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Corrected at 4th printing, 2018.
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