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Iris melanoma TNM staging AJCC UICC 8th edition

Iris melanoma TNM staging AJCC UICC 8th edition
Primary tumor (T)
T category T criteria
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
T1 Tumor limited to the iris
T1a Tumor limited to the iris, not more than 3 clock hours in size
T1b Tumor limited to the iris, more than 3 clock hours in size
T1c Tumor limited to the iris with secondary glaucoma
T2 Tumor confluent with or extending into the ciliary body, choroid, or both
T2a Tumor confluent with or extending into the ciliary body, without secondary glaucoma
T2b Tumor confluent with or extending into the ciliary body and choroid, without secondary glaucoma
T2c Tumor confluent with or extending into the ciliary body, choroid, or both, with secondary glaucoma
T3 Tumor confluent with or extending into the ciliary body, choroid, or both, with scleral extension
T4 Tumor with extrascleral extension
T4a Tumor with extrascleral extension ≤5 mm in largest diameter
T4b Tumor with extrascleral extension >5 mm in largest diameter
NOTE: Iris melanomas originate from, and are predominately located in, this region of the uvea. If less than half the tumor volume is located within the iris, the tumor may have originated in the ciliary body, and consideration should be given to classifying it accordingly.
Regional lymph nodes (N)
N category N criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node involvement
N1 Regional lymph node metastases or discrete tumor deposits in the orbit
N1a Metastasis in one or more regional lymph node(s)
N1b No regional lymph nodes are positive, but there are discrete tumor deposits in the orbit that are not contiguous to the eye (choroidal and ciliary body)
Distant metastasis (M)
M category M criteria
M0 No distant metastasis by clinical classification
M1 Distant metastasis
M1a Largest diameter of the largest metastasis ≤3.0 cm
M1b Largest diameter of the largest metastasis 3.1-8.0 cm
M1c Largest diameter of the largest metastasis ≥8.1 cm
TNM: tumor, node, metastasis; AJCC: American Joint Committee on Cancer; UICC: Union for International Cancer Control.
Used with permission of the American College of Surgeons, Chicago, Illinois. The original source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2017) published by Springer International Publishing. Corrected at 4th printing, 2018.
Graphic 110765 Version 9.0

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