Histopathology of pancreatic transplant rejection

(A) Septal lymphocytic and eosinophilic inflammation (arrows) is common in acute cellular rejection of pancreas allografts. Pancreatic acini are seen in the lower left (asterisk; H&E 200x).
(B) The small artery seen in the center of the field shows prominent intimal arteritis (arrow). This finding is associated with more severe forms of both acute cellular rejection and antibody-mediated rejection of the pancreas allograft (H&E 400x).
(C) Lymphocytic and eosinophilic acinar inflammation (arrows) with associated acinar cell injury in acute cellular rejection (asterisks; H&E 400x).