Merkel cell carcinoma overall survival with local disease only

(A) Five-year OS of 6127 patients with local Merkel cell carcinoma only (clinically and, if known, pathologically node negative) in the NCDB, stratified by T category (≤2 cm, T1; >2 cm, T2/3; involving fascia, muscle, cartilage, or bone, T4). Eleven patients with in situ disease (Tis) were excluded. Categories T2 (n = 1511) and T3 (n = 311) were combined because of overlapping survival curves.
(B) Five-year OS of 2013 patients with Merkel cell carcinoma in the NCDB with clinical staging only for local disease (cN0 pNx; ie, pathological nodal staging was not performed). Of these patients, 1272 presented with clinical stage I, 675 presented with clinical stage IIA, and 66 presented with clinical stage IIB. Survival rates of clinically staged nodal and distant metastases are not depicted; refer to Additional Factors Recommended for Clinical Care for details.